Santiago Fraga

ORCID: 0000-0003-3917-9960
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About
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Research Areas
  • Marine Toxins and Detection Methods
  • Marine and coastal ecosystems
  • Protist diversity and phylogeny
  • Microbial Community Ecology and Physiology
  • Marine Biology and Ecology Research
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Neuroscience of respiration and sleep
  • Marine and coastal plant biology
  • Diatoms and Algae Research
  • Marine Biology and Environmental Chemistry
  • Pharmaceutical studies and practices
  • Aquatic Invertebrate Ecology and Behavior
  • Protein Hydrolysis and Bioactive Peptides
  • Marine Bivalve and Aquaculture Studies
  • Nicotinic Acetylcholine Receptors Study
  • Algal biology and biofuel production
  • Marine Ecology and Invasive Species
  • Alzheimer's disease research and treatments
  • Geology and Paleoclimatology Research
  • Chemical synthesis and alkaloids
  • Plant and animal studies
  • Cholinesterase and Neurodegenerative Diseases
  • Galician and Iberian cultural studies
  • Safe Handling of Antineoplastic Drugs
  • Mediterranean and Iberian flora and fauna

Hospital de São João
2019-2024

Promotora de Informaciones (Spain)
2022

Instituto Español de Oceanografía
2011-2020

Apis Flora (Brazil)
2018

Instituto de Investigacións Mariñas
2012

Centro Oceanográfico de Vigo
2010-2011

University of Urbino
2008

Several isolates of epiphytic dinoflagellates belonging to the genera Ostreopsis Schmidt and Coolia Meunier from western Mediterranean Sea were examined by LM EM, toxicity assays, internal transcribed spacer (ITS) regions nuclear rDNA, 5.8S rDNA sequenced. Morphological comparisons based on analyses cell shape, size, thecal plates, surface ornamentation revealed two distinct species in Mediterranean: O . cf. siamensis Catalan, Andalusian, Sicilian coasts O. ovata Fukuyo Ligurian coast,...

10.1111/j.1529-8817.2005.04011.x article EN Journal of Phycology 2005-01-31

AIMSDeposition of cerebral amyloid plaques is a hallmark feature Alzheimer's disease (AD) and reduction load widely regarded as the most promising therapy for disease.We investigated ability five-residue ␤-sheet breaker peptide (iA␤5p) with improved pharmacological properties to reduce deposition damage in vivo using two different transgenic mice models AD.

10.1096/fj.01-0841fje article EN The FASEB Journal 2002-04-10

Amyloid plaques in brain, composed of aggregates amyloid-β peptide, play a central role the pathogenesis Alzheimer's disease and represent good target for treatment. We have shown previously that 5-amino acid β-sheet breaker peptide (iAβ5p), end-protected, has ability to induce dramatic reduction amyloid deposition two different transgenic models (Permanne, B., Adessi, C., Saborio, G. P., Fraga, S., Frossard, M.-J., Dewachter, I., Van Dorpe, J., Banks, W. A., Leuven, F., Soto, C. (2002)...

10.1074/jbc.m211976200 article EN cc-by Journal of Biological Chemistry 2003-04-01

Abstract Aim Ostreopsis is a benthic and epiphytic dinoflagellate producing potent toxins widespread in tropical warm temperate coastal areas world‐wide. We tested the hypothesis that as it benthic, would show distinct biogeographical patterns comparison with planktonic species. Here, we analyse sequence variability ribosomal DNA markers to provide first phylogeographical study of this toxic dinoflagellate. Location Mediterranean Sea, Atlantic Ocean, Pacific Ocean. Methods Ribosomal data...

10.1111/j.1365-2699.2009.02265.x article EN Journal of Biogeography 2010-02-18

MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 465:33-52 (2012) - DOI: https://doi.org/10.3354/meps09879 Pigment-based chloroplast types in dinoflagellates Manuel Zapata1,†, Santiago Fraga2, Francisco Rodríguez2,*, José L. Garrido1 1Instituto de Investigaciones Marinas, CSIC, c/ Eduardo Cabello 6, 36208 Vigo, Spain 2Instituto Español Oceanografía, Subida...

10.3354/meps09879 article EN Marine Ecology Progress Series 2012-07-02

Species of the dinoflagellate genus Gambierdiscus are cause Ciguatera Fish Poisoning, common in tropical areas. Nevertheless, until recently this syndrome was not reported NE Atlantic Ocean. A new photosynthetic species, silvae sp. nov. is described based on samples taken from tide pools rocky shores Canary Islands (NE Ocean). Its morphology studied by light and scanning electron microscopy. The species anterioposteriorly compressed, lenticular shape with an epitheca slightly higher than...

10.1016/j.protis.2014.09.003 article EN cc-by Protist 2014-10-09

Shallow, well--illuminated coastal waters from tropical to temperate latitudes are attractive environments for humans.Beaches and coral reefs have provided lodging food communities centuries.Unfortunately, regions traditionally been threatened by outbreaks of the toxic benthic dinoflagellate Gambierdiscus associated Ciguatera Fish Poisoning.The ciguatoxins produced bioaccumulated in reef fishes responsible most common algal toxin--related illnesses, globally affecting greatest number victims...

10.5670/oceanog.2017.108 article EN cc-by Oceanography 2017-03-01

Any technique developed to enumerate plankton must take into account the size structure of community. Automatic sampling devices be capable analysing a minimum number cells largest cover whole range intended sampled effectively. The Flow Cytometer And Microscope (FlowCAM®) has been used in last decade estimate Few attempts, however, have made compare FlowCAM measurements with results provided by traditional microscopy methods for size-structure estimations. can operate three working modes:...

10.1093/plankt/fbr012 article EN Journal of Plankton Research 2011-03-01

In the present study geographical distribution, abundance and composition of Gambierdiscus was described over a 600 km longitudinal scale in Canary Islands. Samples for cell counts, isolation identification were obtained from five islands (El Hierro, Tenerife, Gran Canaria, Fuerteventura Lanzarote). Average densities spp. between 0 2200 cells g−1 blot dry weight macrophyte recorded. Morphological (light microscopy SEM techniques) molecular analyses (LSU SSU rDNA sequencing cultures single...

10.1016/j.hal.2017.06.009 article EN cc-by-nc-nd Harmful Algae 2017-07-01

Cyst studies carried out in 2002–2003 on Mediterranean Sea sediment from seven different sites along the Catalan and Balearic coasts (Western Mediterranean) revealed a higher diversity of Alexandrium species region than was previously known. The cysts eight toxigenic, marine dinoflagellate genus are described, some, such as A. kutnerae, margalefi, peruvianum pseudogoniaulax, reported area for first time. This is also record resting taylori sediment, description known to date kutnerae...

10.1080/09670260600810360 article EN European Journal of Phycology 2006-08-01

A phylogenetic analysis of the genus Alexandrium, including both most common and rare species from coastal areas Mediterranean Sea was carried out. Nucleotide sequences 5.8 S gene Internal Transcribed Spacer regions rRNA operon were examined analysed together with isolates Alexandrium spp. elsewhere in world. These rDNA ribosomal markers useful delineating position genus, as well determining relationships among within each collected different localities. Results phylogeographical analyses...

10.1080/09670260701783730 article EN European Journal of Phycology 2008-05-01

Both benthic and planktic dinoflagellates can produce harmful algal blooms. However most of the studies conducted so far emphasized on species. In present review, we assessed main ecological factors affecting population dynamics bloomforming dinoflagellates, with particular emphasis Ostreopsis Gambierdiscus. Based basic equation dynamics, mainly focused growth, predation, mortality, immigration dispersion. Factors determining dinoflagellate populations are very different from well-studied...

10.7872/crya.v33.iss2.2011.171 article EN Cryptogamie Algologie 2012-05-01

proposed to reject the name Gonyaulax catenella Whedon & Kof., basionym of Alexandrium (Whedon Kof.) Balech in order permit usage more recent fundyense Balech.The proposal was based on Art.56.1 ICN (McNeill al. Regnum Veg.154.2012), which states that a would cause disadvantageous nomenclatural change may be for rejection.In our opinion authors do not provide necessary background this and misinterpret some data literature.In following we argue should rejected as its acceptance will serious...

10.12705/643.15 article EN Taxon 2015-06-01
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