Wu Zhuang

ORCID: 0000-0002-6639-3607
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Treatments and Studies
  • Cancer-related gene regulation

Fujian Provincial Cancer Hospital
2024

Fujian Medical University
2024

Abstract Objective Non‐small cell lung cancer (NSCLC) is a prevailing LC characterized by poor outcomes. AlkB homolog 5 (ALKBH5) functions as tumor suppressor in several cancers. This study delved into the role of ALKBH5 NSCLC development. Methods TCGA database predicted expression patients. levels and human bronchial epithelial cells were determined. pcDNA3.1‐ALKBH5/NC, pcDNA3.1‐SLC7A11/NC, ferrostatin‐1 used to explore interactions among ALKBH5, SLC7A11, ferroptosis. SLC7A11 mRNA its...

10.1002/tox.24272 article EN Environmental Toxicology 2024-04-20
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