A5101938506- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Periodontal Regeneration and Treatments
- Pomegranate: compositions and health benefits
- Wound Healing and Treatments
- Magnetic properties of thin films
- Extracellular vesicles in disease
- Garlic and Onion Studies
- Craniofacial Disorders and Treatments
- Bone health and treatments
- Bone fractures and treatments
- Oral and Maxillofacial Pathology
- Liver physiology and pathology
- Sesame and Sesamin Research
- Autophagy in Disease and Therapy
- Oral and gingival health research
- bioluminescence and chemiluminescence research
- Liver Diseases and Immunity
- Fibroblast Growth Factor Research
- Liver Disease Diagnosis and Treatment
- Nanoporous metals and alloys
- Neuropeptides and Animal Physiology
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Biofuel production and bioconversion
- Oral microbiology and periodontitis research
Yanbian University
2024
Air Force Medical University
2020-2024
Sichuan University
2018-2023
West China Hospital of Sichuan University
2018-2023
National Clinical Research
2021
South China University of Technology
2020
University of Science and Technology of China
2018
Hefei University
2018
Harbin Institute of Technology
2011
Extracellular vesicles (EVs) derived from living cells play important roles in donor cell-induced recipient tissue regeneration. Although numerous studies have found that undergo apoptosis after implantation an ischemic-hypoxic environment, the played by EVs released apoptotic are largely unknown. In this study, we obtained (apoVs) human deciduous pulp stem and explored their effects on dental regeneration process. Our work showed apoVs were ingested endothelial (ECs) elevated expression of...
Abstract Objectives Pulp regeneration brings big challenges for clinicians, and vascularization is considered as its determining factor. We previously accomplished pulp with autologous stem cells from deciduous teeth (SHED) aggregates implantation in teenager patients, however, the underlying mechanism needs to be clarified regenerating adults. Serving an important effector of mesenchymal (MSCs), exosomes have been reported promote angiogenesis tissue effectively. Here, we aimed investigate...
Inflammation plays a crucial role in triggering regeneration, while inadequate or chronic inflammation hinders the regenerative process, resulting refractory wounds. Inspired by ideal regeneration mode lower vertebrates and human oral mucosa, realigning dysregulated to heightened acute response provides promising option for wound therapy. Neutrophils play important roles initiation resolution. Here, hybrid biomaterial is used stimulate transiently inflammatory responses precise tempospatial...
Abstract The interplay between bacteria and their host influences the homeostasis of human immune microenvironment, this reciprocal interaction also affects process tissue damage repair. A variety immunomodulatory commensal reside in body, capable delivering membrane vesicles (MVs) to cells regulate local microenvironment. This research revealed, for initial time, significant enhancement mucosal cutaneous wound healing by MVs secreted Lactobacillus reuteri (RMVs) through modulation...
During pretreatment of lignocellulosic biomass, toxic compounds were released and inhibited the growth fermentation microorganisms. Here global transcriptional response K. marxianus to multiple inhibitors including acetic acid, phenols, furfural HMF, at 42 °C, was studied, via RNA-seq technology. Genes involved in glycolysis pathway, fatty acid metabolism, ergosterol metabolism vitamin B6 B1 metabolic process enriched down-regulated gene set, while genes TCA cycle, respiratory chain, ROS...
The pits and fissures of teeth have high caries susceptibility, sealing these areas is considered as an effective method to prevent caries. However, long-term prophylaxis cannot be maintained because the negative effects derived from technical sensitivity disadvantages materials. Herein, a new strategy proposed occlude fossae by amyloid-mediated biomimetic remineralization. In contrast conventional inward blocking outside fossae, mineralization delivers amyloid-like protein nanofilm into...
Early orthodontic correction of skeletal malocclusion takes advantage mechanical force to stimulate unclosed suture remodeling and promote bone reconstruction; however, the underlying mechanisms remain largely unclear. Gli1+ cells in maxillofacial sutures have been shown participate development damage repair. Nevertheless, it remains be investigated whether these force-induced during treatment malocclusion. In this study, rapid maxillary expansion (RME) mouse models stretch loading cell were...
Zimmermann-Laband Syndrome (ZLS; MIM 135500) is a rare genetic disorder with the main clinical manifestations of gingival fibromatosis and finger/toe nail hypoplasia.
Cleidocranial dysplasia (CCD) is an autosomal-dominant, heritable skeletal and dental disease, involving hypoplastic clavicles, defective ossification of the anterior fontanelle, dentin enamel hypoplasia, supernumerary teeth, which can seriously affect oral mental health patients. Amyloid-like protein aggregation, established by lysozyme conjugated with polyethylene glycol (Lyso-PEG), forms a mineralized nanofilm layer on healthy surface. However, whether it form remineralization in tissues...
As a topological spin texture, magnetic domain walls have soliton-like dynamic behaviors in nanowires, which can be used information transmission and storage technology. Therefore, precisely controlling the dynamic...
Background: The activation of hepatic stellate cells (HSCs) participates in liver fibrosis, and emerging evidences indicate that microRNAs (miRNAs) are abnormally expressed during HSC activation. However, the potential roles miRNAs fibrosis still remain elusive. Methods: differential expression between quiescent activated HSCs was measured by miRNA microarray analysis, which further validated RT-qPCR animal models patients. effect miR-199a-3p on CAV2 examined Western blotting using mimics or...