A5032588552- Viral Infections and Vectors
- Mosquito-borne diseases and control
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Fire effects on ecosystems
- HIV/AIDS Research and Interventions
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Viral Infections and Outbreaks Research
- Virology and Viral Diseases
- Hepatitis C virus research
- Reproductive tract infections research
- Animal Disease Management and Epidemiology
- Invertebrate Immune Response Mechanisms
- Insect symbiosis and bacterial influences
- HIV, Drug Use, Sexual Risk
- Cytomegalovirus and herpesvirus research
- Aquaculture disease management and microbiota
- Syphilis Diagnosis and Treatment
- Virus-based gene therapy research
- Rabies epidemiology and control
- Diabetes Treatment and Management
- Coccidia and coccidiosis research
- COVID-19 Impact on Reproduction
Zhejiang Center for Disease Control and Prevention
2006-2024
Tianjin University
2020-2024
Yunnan Provincial Infectious Disease Hospital
2010-2022
Kunming Medical University
2021
Yunnan Center for Disease Control And Prevention
2021
CAE (Canada)
2005
Zhejiang University
2003-2004
Carbon materials are promising electrocatalysts for renewable energy devices because of their abundant availability, tunability, and structural durability in harsh electrochemical environments. Future large-scale applications require the construction carbon with a clear doping configuration high dopant loading, but this is particularly challenging. In work, we reported molecular weaving strategy using molecules well-defined thiophene–sulfur (S) as precursors to synthesize thiophene–S-doped S...
A reliable disease model mimicking Enterovirus 71 (EV71) infection in humans is essential for understanding pathogenesis and developing a safe effective vaccine. Commonly used rodent models including mouse or rat are not suitable vaccine evaluation because the rodents resistant to EV71 after they reach age of 6 days. In this study, 21-day-old gerbils inoculated intraperitoneally (IP) with non mouse-adapted strain developed neurological lesion-related signs hind limb paralysis, slowness,...
Background Sporadic Japanese encephalitis (JE) cases still have been reported in Zhejiang Province recent years, and concerns about vaccine cross-protection population-level immunity raised off on within the public health sphere. Genotype I (GI) has replaced GIII as dominant genotype Asian countries during past few decades, which caused considerable potential change of epidemiology characteristics effectiveness. The aim this study was to investigate prevalence JE neutralizing antibody its...
Abstract Background Yunnan has the highest rates of HIV in China. Other treatable sexually transmitted infections (STIs) are associated with accelerated transmission and poor ART outcomes, but only diagnosed by syndromic algorithms. Methods We recruited 406 HIV-positive participants for a cross-sectional study (204 ART-naive 202 receiving ART). Blood samples first-voided urine were collected. Real-time polymerase chain reaction methods used diagnosing Chlamydia trachomatis (CT), Neisseria...
Monensin, produced by Streptomyces cinnamonensis, is a polyether ionophore antibiotic widely used as coccidiostat and growth-promoting agent in agricultural industry. In this study, cyclic AMP receptor protein (Crp), the global transcription factor for regulation of monensin biosynthesis, was deciphered. The overexpression antisense RNA silencing crp revealed that Crp plays positive role biosynthesis. sequencing analysis indicated exhibited extensive regulatory effects on genes involved both...
Reduced doses of antiretroviral (ARV) drugs may lower toxicity while preserving efficacy. We aimed to evaluate the efficacy reduced both tenofovir disoproxil fumarate (TDF) and efavirenz for treatment HIV-1 infection. In this open-label, non-inferiority trial, HIV-1-infected antiretroviral-naive adults were randomly assigned receive either a dose anti-retroviral regimen comprised TDF (200 mg), (400 standard lamivudine (300 mg) or regimen. The primary endpoint was proportion participants with...
This study was based on similar physicochemical characteristics of pseudorabies virus (PRV) and African swine fever (ASFV). A cellular model for evaluation disinfectants established with PRV as an alternative marker strain. In the present study, we evaluated disinfection performance commonly used commercialized to provide a reference selection good ASFV disinfectants. addition, (anti-virus) performances four were investigated minimum effective concentration, onset time, action operating...
The aim of this study was to establish a rapid method for constructing infectious clones porcine circovirus type 2 (PCV2). In study, we constructed circular PCV2 by seamless cloning technology, using the clinically isolated strain PCV2-LX as template. Meanwhile, compared with conventional restriction-ligation approach, focusing on