A5001822113- Breast Implant and Reconstruction
- Breast Cancer Treatment Studies
- Reconstructive Surgery and Microvascular Techniques
- Cancer Risks and Factors
- Women's cancer prevention and management
- Cancer Cells and Metastasis
- Nonmelanoma Skin Cancer Studies
- Childhood Cancer Survivors' Quality of Life
- Ovarian cancer diagnosis and treatment
- Radiomics and Machine Learning in Medical Imaging
- Multiple and Secondary Primary Cancers
- MRI in cancer diagnosis
- Reconstructive Facial Surgery Techniques
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive Biology and Fertility
- Cancer Diagnosis and Treatment
- Wnt/β-catenin signaling in development and cancer
- Clinical practice guidelines implementation
- Angiogenesis and VEGF in Cancer
- Prenatal Screening and Diagnostics
- Cancer and biochemical research
- HER2/EGFR in Cancer Research
- BRCA gene mutations in cancer
- Global Cancer Incidence and Screening
- Management of metastatic bone disease
Hospital Nossa Senhora das Graças
2002-2024
Universidade Federal do Paraná
2011-2023
Universidade Positivo
2022
Hospital de Clínicas Universidade Federal do Paraná
2014-2020
Gene Therapy Laboratory
2020
The Princess Grace Hospital
2019
Hospital de Clínicas
2007
Breast cancer is a very heterogeneous disease. The intrinsic molecular subtypes can explain the intertumoral heterogeneity and stem cell (CSC) hypothesis intratumoral of this kind tumor. CD44+/CD24- phenotype ALDH1 expression are major CSC markers described in invasive breast cancer. In present study, 144 samples carcinoma, no special type were distributed 15 tissue microarrays (TMA) then evaluated for to understand importance these clinical aspects classified into four according...
Objective: The aim of this study was to report the results prepectoral direct-to implant (DTI) reconstruction in nipple-sparing mastectomy (NSM), without acellular dermal matrices (ADM) or mesh. Methods: Multicenter cohort patients, from 2013 2020, where all sizes and types breasts, either for prophylactic therapeutic surgical purposes were included, except those with previously failed reconstruction, previous radiotherapy severe skin damage, locally advanced breast cancer, gigantomasty,...
Axillary reverse mapping (ARM) is a new technique developed with the aim of reducing lymphedema rates by preserving lymphatic drainage upper limbs during sentinel lymph node biopsy and axillary dissection (ALND). However, it unclear whether preservation these nodes affects oncological risk. The present study evaluated presence metastases in ARM nodes.A total 45 patients underwent ALND. Blue dye was used for localization. All nodes, including were removed sent separately pathological...
Marking positive lymph nodes (LNs) before neoadjuvant chemotherapy (NAC) may improve the accuracy of sentinel node biopsy (SLNB). The aim this study was to determine feasibility marking LNs with 4% carbon microparticle suspension (CMS) NAC and evaluate if technique would SLNB identification rate.A prospective patients cT1-T4, cN1-N2 breast cancer who underwent US-guided fine-needle aspiration (FNAB) suspected concomitant CMS performed. After NAC, marked those Patent Blue V dye (PBV) were...
Background: Three-dimensional (3D) imaging using computer simulations is an evolving technology. There a lack of strong data on the use this technology for oncoplastic (OP) and reconstructive surgery. Methods: A prospective, randomized, single-center trial including breast cancer patients undergoing OP or mastectomy with immediate reconstruction implant (IBR) enrolled from November 2019 to October 2021 at Hospital Nossa Senhora das Graças, Breast Unit in Curitiba, Brazil. Both those IBR...
A associação de câncer e gravidez é uma situação desafiadora para o médico. Normalmente necessário uso quimioterapia radioterapia, dependendo do tipo estádio em que diagnosticado. pode oferecer riscos à saúde fetal e, por outro lado, se não for realizado nenhum tratamento até nascimento, a vida da mãe ficar risco. Inicialmente, acreditava-se preocupação deveria ser com mãe, considerando os fetais. Este conceito vem sofrendo mudanças, na tentativa harmonizar adequado preservação integridade...
OBJETIVOS: avaliar a quimioterapia neoadjuvante no câncer localmente avançado do colo uterino, por meio da sua aceitabilidade, tolerabilidade, toxicidade, taxa de complicações cirúrgicas, resposta, operabilidade e sobrevida em 5 anos. MÉTODOS: foram incluídas 60 mulheres com uterino (IIB IIIB), submetidas à doxorrubicina-bleomicina-cisplatina. Aquelas que se tornaram operáveis após cirurgia Wertheim-Meigs, seguida radioterapia pélvica complementar. Nas pacientes não foi possível...
Infection and exposure of the implant are some most common concerning complications after implant-based breast reconstruction. Currently, there is no consensus on management these complications. The aim present study was to review our cases a clinical protocol. We conducted retrospective consecutive patients submitted reconstruction between 2014 2016. All were managed according specific structured Implant occurred in 33 out 277 (11.9%) reconstructions. Among these, two had history...
Background Routine use of magnetic resonance imaging (MRI) in the staging patients with early breast cancer is still controversial. Oncoplastic surgery (OP) allows for wider resections without compromising aesthetic results. This study aimed to assess impact preoperative MRI on surgical planning and indications mastectomy. Methods Prospective including T1-T2 treated between January 2019 December 2020 Breast Unit Hospital Nossa Senhora das Graças Curitiba, Brazil. All had indication...
Abstract Introduction: Surgery is the mainstay treatment of breast cancer and has been improving in aesthetic outcomes even locally advanced disease. Radical mastectomies are being replaced by less aggressive surgeries with immediate reconstruction. Nipple-Sparing Mastectomy (NSM) preserves Nipple Areolar Complex (NAC) along entire skin envelope associated better results quality life, patient satisfaction. Since NSM a relatively recent technique few studies have shown feasibility after...
foram tumores multifocais, 1/29 (3,4%) foi multicêntrico, 5/29 (17%) contralaterais e 9/29 (31%) apresentaram tamanho de tumor maior que 10 mm na RM.Das 22 pacientes lesões adicionais RM, 15 (68,2%) carcinomas invasivos no exame anatomopatológico definitivo.
Introdução: O câncer de endométrio é o terceiro ginecológico mais frequente em mulheres no Brasil. sangramento uterino anormal e espessamento endometrial são as apresentações comuns da doença. objetivo desse estudo foi encontrar a relação entre sangramento, obesidade diagnóstico do na paciente pós-menopausa. Métodos: Trata-se um retrospectivo qual realizado levantamento dados das pacientes pós-menopausa submetidas à curetagem uterina prova (CUP) devido queixa e/ou apresentarem endometrial,...