A5040317059- Pharmaceutical and Antibiotic Environmental Impacts
- Wastewater Treatment and Reuse
- biodegradable polymer synthesis and properties
- Advanced Polymer Synthesis and Characterization
- Water Quality and Pollution Assessment
- Effects and risks of endocrine disrupting chemicals
- Environmental Toxicology and Ecotoxicology
- Muscle Physiology and Disorders
- Fuel Cells and Related Materials
- Photonic Crystals and Applications
- Retinal Development and Disorders
- Electrocatalysts for Energy Conversion
- Toxic Organic Pollutants Impact
- Cellular transport and secretion
- Receptor Mechanisms and Signaling
- Covalent Organic Framework Applications
- Muscle metabolism and nutrition
- Glutathione Transferases and Polymorphisms
- Genetics, Aging, and Longevity in Model Organisms
- Surfactants and Colloidal Systems
- Microplastics and Plastic Pollution
- Spinal Cord Injury Research
- Constructed Wetlands for Wastewater Treatment
- Microbial Metabolic Engineering and Bioproduction
- Cardiomyopathy and Myosin Studies
Beijing Chao-Yang Hospital
2025
Capital Medical University
2025
Xuzhou Medical College
2017-2024
Shihezi University
2024
Xuzhou Central Hospital
2024
Southeast University
2022-2023
Nanjing Drum Tower Hospital
2019-2023
Nanjing University
2013-2022
State Key Laboratory of Pharmaceutical Biotechnology
2016-2022
Shanghai Lixin University of Accounting and Finance
2022
Peanut is one of the most important oil crops in world, growth and productivity which are severely affected by salt stress. 24-epibrassinolide (EBL) plays an role stress resistances. However, roles exogenous EBL on tolerance peanut remain unclear. In this study, seedlings treated with 150 mM NaCl or without spray were performed to investigate resistance. Under conditions, foliar application 0.1 µM increased activity catalase thereby could eliminate reactive oxygen species (ROS). Similarly,...
Abstract The development of low‐cost non‐precious‐metal electrocatalysts with high activity and stability in the oxygen reduction reaction (ORR) remains a great challenge. Heteroatom‐doped carbon materials are receiving increased attention research as effective catalysts. However, uncontrolled doping heteroatoms into matrix tends to inhibit catalyst. Here, situ activation uniquely structured nitrogen‐doped carbon/Ni composite catalyst for ORR is demonstrated. This well‐designed composed...
Force production and maintenance in smooth muscle is largely controlled by myosin regulatory light chain (RLC) phosphorylation, which relies on a balance between Ca(2+)/calmodulin-dependent kinase (MLCK) phosphatase (MLCP) activities. MYPT1 the subunit of MLCP that biochemically inhibits activity via T694 or T852 phosphorylation vitro. Here we separately investigated contribution these two sites bladder muscles establishing single point mutation mouse lines, T694A T852A, found T694, but not...
CoB/Ni-foam was directly formed on a Ni-foam substrate using the electroless plating method. A membraneless DBFC with (7EP) as an anode showed maximum power density of 230 mW cm<sup>−2</sup>.
Significance The polar overdominance inheritance of callipyge sheep is an unusual mode non-Mendelian inheritance. We established a mouse line with deletion the microRNA (miR) 379/miR-544 cluster and assessed role this in Our results showed that maternally expressed miR-379/miR-544 might regulate skeletal muscle growth through imprinted Delta-like 1 homolog ( Dlk1 ) gene. This report revealed molecular mechanism
The toxicity of single and combined mixtures 2,4-dichlorophenol (2,4-DCP), 2,4,6-trichlorophenol (2,4,6-TCP), pentachlorophenol (PCP) to Daphnia magna was studied. ranking these three chlorophenols (CPs) PCP > 2,4-DCP 2,4,6-TCP. toxic units (TU) approach used estimate the effects in experiments, median effective concentration (EC50) values were 0.87–1.21 0.46–0.59 for binary ternary mixtures, respectively. Response surface models General Linear Models (R2 0.90, residual deviation < 3.25)...
Smooth muscle sphincters exhibit basal tone and control passage of contents through organs such as the gastrointestinal tract; loss this leads to disorders faecal incontinence. However, molecular mechanisms underlying remain unknown. Here, we show that deletion myosin light-chain kinases (MLCK) in smooth cells from internal anal sphincter (IAS-SMCs) abolishes tone, impairing defecation. Pharmacological regulation ryanodine receptors (RyRs), L-type voltage-dependent Ca(2+) channels (VDCCs) or...
Both chronic obstructive pulmonary disease (COPD) and asthma are severe respiratory diseases. Bitter receptor–mediated bronchodilation is a potential therapy for asthma, but the mechanism underlying agonistic relaxation of airway smooth muscle (ASM) not well defined. By exploring ASM bitter substances, we observed that pretreatment with substances nearly abolished methacholine (MCh)-induced increase in cell (ASMC) calcium concentration, thereby suppressing calcium-induced contraction...
The stability of perfluorooctanoate (PFOA) coupled with its wide use cause serious concerns regarding potential risk to human health. molecular mechanisms PFOA-induced hepatotoxicity relevant health was investigated using both in vivo (mouse model) and vitro (human hepatocyte cells, HL-7702) techniques. Both male female Balb/c mice were administered PFOA at 0.05, 0.5, or 2.5 mg/kg-d for 28-d, serum concentrations after exposure being found environmentally levels. Liver samples examined...
Neurite outgrowth requires coordinated cytoskeletal rearrangements in the growth cone and directional membrane delivery from neuronal soma. As an essential Rho guanine nucleotide exchange factor (GEF), TRIO is necessary for dynamics during neurite outgrowth, but its participation unclear. Using co-localization studies, live-cell imaging, fluorescence recovery after photobleaching analysis, along with assay various biochemical approaches, we here report that mouse cerebellar granule neurons,...
Abstract Covalent triazine frameworks (CTFs) and their derivative N‐doped carbons have attracted much attention for application in energy conversion storage. However, previous studies mainly focused on developing new building blocks optimizing synthetic conditions. The use of isometric to control the porous structure fundamentally understand structure–property relationships rarely been reported. In this work, two are used produce CTFs with controllable pore geometries. as‐prepared CTF...