A5057826032- Bayesian Methods and Mixture Models
- Gene expression and cancer classification
- Bioinformatics and Genomic Networks
- Health Systems, Economic Evaluations, Quality of Life
- Statistical Methods and Bayesian Inference
- Statistical Methods and Inference
- Advanced Radiotherapy Techniques
- Chronic Disease Management Strategies
- Statistical Distribution Estimation and Applications
- Shoulder Injury and Treatment
- Tendon Structure and Treatment
- Colorectal Cancer Screening and Detection
- Medical Imaging Techniques and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Radiation Dose and Imaging
- Cancer survivorship and care
- Health disparities and outcomes
- Global Maternal and Child Health
- Ovarian cancer diagnosis and treatment
- Birth, Development, and Health
- Parasites and Host Interactions
- Myofascial pain diagnosis and treatment
- Face and Expression Recognition
- Kruppel-like factors research
- Skin Protection and Aging
Griffith University
2016-2025
CReATe Fertility Centre
2025
Gold Coast Health
2025
William Harvey Research Institute
2024
Curtin University
2024
Gold Coast Hospital
2017-2024
Bridge University
2024
Bond University
2024
Deakin University
2024
Concord Hospital
2024
Long-term obesity after pregnancy is associated with prior to and retention of weight postpartum. This study aims identify socioeconomic differences in prepregnancy body mass index, quantify the impact on birth outcomes, determinants postpartum retention.
Almost 10% of hospitalised patients experience acute deterioration requiring emergency intervention. Language barriers can impede patient assessment and health outcomes. The objective this study was to explore the experiences adult inpatients whose preferred language not English, who received care from intensive unit (ICU) outreach team. An explanatory sequential two-phase mixed-method design used. A retrospective audit undertaken characteristics outcomes for recipients ICU team care,...
To compare the effectiveness and cost-effectiveness of eccentric loading exercises (ELE) with prolotherapy injections used singly in combination for painful Achilles tendinosis.A single-blinded randomised clinical trial. The primary outcome measure was VISA-A questionnaire a minimum clinically important change (MCIC) 20 points.Five Australian care centres.43 patients mid-portion tendinosis commenced 40 completed treatment protocols.Participants were to 12-week program ELE (n=15), or...
Heightened psychological distress after cancer is common but likely highly heterogeneous. This raises potential challenges in how and when to target services; however, data describing longitudinal patterns of are limited. study describes the long term outcomes for colorectal (CRC) survivors trajectories adjustment over time.A prospective survey a population-based sample 1966 CRC assessed sociodemographic variables, perceived social support distress, including subtypes anxiety, depression...
Abstract Background To describe trajectories of health‐related quality life (QoL), satisfaction, and psychological adjustment for men with prostate cancer over the medium to long term identify predictors poorer outcomes using growth mixture models. Methods One‐thousand sixty‐four (82.4% response) diagnosed were recruited close diagnosis assessed a 72‐month (6‐year) period self‐report assessment QoL, cancer‐related distress, specific antigen anxiety. Urinary, bowel, sexual function also...
Abstract Background Women have better survival than men patients with colorectal cancer (CRC), but the extent to which this is due multimorbidity unclear. Methods A population-based study of 1843 diagnosed CRC in Australia. Data included patient’s demographics, multimorbidity, tumour histology, stage, and treatment. We estimated risks all-cause mortality cause-specific or non-cancer causes. Results Men had lower women (P ≤ 0.010) amongst those at Stages I-III (15-year survival: 56.0% vs...
Abstract Motivation: The clustering of gene profiles across some experimental conditions interest contributes significantly to the elucidation unknown function, validation discoveries and interpretation biological processes. However, this problem is not straightforward as genes are all independently distributed expression levels may have been obtained from an design involving replicated arrays. Ignoring dependence between structure data can result in important sources variability experiments...
Abstract Background High birth weight has serious adverse impacts on chronic health conditions and development in children. This study identifies the social determinants obstetric complications of high adjusted for gestational age baby gender. Methods Pregnant women were recruited from three maternity hospitals South-East Queensland Australia during antenatal clinic visits. A questionnaire was completed by each participant to elicit information eco-epidemiological exposures. Perinatal...
Multimorbidity is becoming more prevalent. Previously-used methods of assessing multimorbidity relied on counting the number health conditions, often in relation to an index condition (comorbidity), or grouping conditions based body organ systems. Recent refinements statistical approaches have resulted improved capture patterns multimorbidity, allowing for identification nonrandomly occurring clusters multimorbid conditions. This paper aims identify nonrandom multimorbidity.The Australian...
Abstract Background This longitudinal study describes the five year trajectories of health-related quality life (HR-QOL) and satisfaction in long term colorectal cancer survivors. Patients methods A population-based sample 1966 survivors were surveyed at six time points from months to years post-diagnosis. Predictor variables were: socio-demographic variables, optimism; threat appraisal; perceived social support. Quality was assessed with Functional Assessment Cancer Therapy-Colorectal...
Selenium binding protein 1 (SELENBP1) was identified to be the most significantly down-regulated in ovarian cancer cells by a membrane proteome profiling analysis. SELENBP1 expression levels 4 normal ovaries, 8 benign tumors, 12 borderline tumors and 141 invasive cancers were analyzed with immunohistochemical assay. reduced 87% cases of (122/141) (p<0.001). Cox multivariate analysis within tissues showed that score potential prognostic indicator for unfavorable prognosis (hazard ratio [HR],...
Aldehyde dehydrogenases belong to a superfamily of detoxifying enzymes that protect cells from carcinogenic aldehydes. Of the superfamily, ALDH1A1 has gained most attention because current studies have shown its expression is associated with human cancer stem cells. However, only one 19 ALDH subfamilies currently known. The purpose present study was determine if and activities other major isozymes are ovarian sphere cultures.Immunohistochemistry used delineate isozyme localization in...
Preventive chemotherapy is the current global control strategy for schistosomiasis. The WHO target coverage rate at least 75% school-aged children. In Philippines, reported national (43.5%) far below target. This study examined factors associated with non-compliance to mass drug administration.A cross-sectional survey was conducted in 2015 among 2189 adults province of Northern Samar, Philippines using a structured face-to-face questionnaire.The overall administration (MDA) last treatment...
International governments’ COVID-19 responses must balance human and economic health. Beyond slowing viral transmission, strict lockdowns have severe consequences. This work investigated response stringency, quantified by the Oxford Government Response Tracker’s Stringency Index, examined how restrictive interventions affected infection rates gross domestic product (GDP) in China OECD countries. Accounting for timing, imposed most stringent restrictions, while Sweden Japan were least...
In systems biomedicine, an experimenter encounters different potential sources of variation in data such as individual samples, multiple experimental conditions, and multi-variable network-level responses. multiparametric cytometry, which is often used for analyzing patient issues are critical. While computational methods can identify cell populations without the ability to automatically match them across it difficult compare characterize typical experiments, those responding various...
Abstract Objective This paper examines the direct and intermediary relationships between life stress, stress appraisal, resilience, increased anxiety depressive symptoms in Australian women after cancer treatment. Methods Data examined from 278 aged 18 years older previously treated for breast, gynaecological, or blood cancer, participating Women's Wellness Cancer Program. Serial mediation models interrogated effect of stressful events (List Threatening Experiences—Modified) mediated by...
Abstract Aim This study aimed to determine how endometriosis affects the quality of life partners women who suffer from this disease and it impacts their relationships, finances, mental states, daily living. Methods was a questionnaire‐based cohort that took place at large tertiary hospital gynecology unit, which covered two sites. Fifty‐one had surgically diagnosed agreed participate in returned completed surveys. Results Ninety‐two percent ( n = 46) reported negative feelings about...