- Nanoparticle-Based Drug Delivery
- Polysaccharides and Plant Cell Walls
- Advanced Cellulose Research Studies
- Diamond and Carbon-based Materials Research
- Biofuel production and bioconversion
- RNA Interference and Gene Delivery
- Glycosylation and Glycoproteins Research
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Hydrogels: synthesis, properties, applications
- GABA and Rice Research
- Ubiquitin and proteasome pathways
- Microbial Metabolic Engineering and Bioproduction
- Selenium in Biological Systems
- RNA modifications and cancer
- Polysaccharides Composition and Applications
- Cancer, Hypoxia, and Metabolism
- MicroRNA in disease regulation
- Galectins and Cancer Biology
- Carbohydrate Chemistry and Synthesis
- Advanced Drug Delivery Systems
- Polymer-Based Agricultural Enhancements
- Dendrimers and Hyperbranched Polymers
- Force Microscopy Techniques and Applications
- Drug Transport and Resistance Mechanisms
Central China Normal University
2014-2025
Westlake University
2025
Guiyang Medical University
2015-2025
Xi'an Jiaotong University
2024-2025
Hangzhou Xixi hospital
2025
Nanjing Agricultural University
2020-2024
Affiliated Hospital of Guizhou Medical University
2015-2024
Changchun Normal University
2024
Zhejiang University
2023-2024
Anhui University of Traditional Chinese Medicine
2019-2023
Abstract O-GlcNAc modification plays critical roles in regulating the stress response program and cellular homeostasis. However, systematic multi-omics studies on regulated mechanism have been limited. Here, comprehensive data are obtained by a chemical reporter-based method to survey function human breast cancer cells stimulated with genotoxic agent adriamycin. We identify 875 stress-induced chromatin-associated proteins (OCPs), including 88 transcription factors cofactors (OCTFs),...
Abstract Intercropping, a green and sustainable planting pattern, has demonstrated positive effects on plant growth the soil environment. However, there is currently little research influence of intercropping leguminous plants using them as manure environment tea quality. During profuse flowering period Chinese milkvetch, contents amino acids soluble sugar in with soybean increased by 6.89 54.58%. Moreover, was 27.42% increase ammonium nitrogen 21.63% available nitrogen. When milkvetch...
Chemoresistance has become a major obstacle to the success of cancer therapy, but mechanisms underlying chemoresistance are not yet fully understood. O-GlcNAcylation is post-translational modification that regulated by hexosamine biosynthetic pathway (HBP) and an important role in wide range cellular functions. Here we assessed investigated mechanisms. The results showed HBP cell regulating O-GlcNAcylation. An increase levels indicates increased resistance cells chemotherapy. Acute treatment...
Inflammatory breast cancer (IBC) is the most aggressive type of advanced characterized by rapid proliferation, early metastatic development and poor prognosis. Since there are few preclinical models IBC, a general lack understanding complexity disease. Recently, we have developed new model IBC derived from pleural effusion woman with secondary IBC. FC-IBC02 cells triple negative form clusters (mammospheres) in suspension that strongly positive for E-cadherin, β-catenin TSPAN24, all adhesion...
Our previous study showed that COPPER-CONTAINING AMINE OXIDASE (CuAO) and AMINOALDEHYDE DEHYDROGENASE (AMADH) could regulate the accumulation of γ-aminobutyric acid (GABA) in tea through polyamine degradation pathway. However, their biological function drought tolerance has not been determined. In this study, Camellia sinensis (Cs) CsCuAO1 associated with CsAMADH1 conferred tolerance, which modulated GABA levels plants. The results exogenous spraying effectively alleviated drought-induced...
In this paper, micromechanical modelling and simulation were performed for unidirectional fibre reinforced composites subjected to transverse in-plane shear by finite element method. Representative volume consisting of fibre, matrix interface was established the simulation, considering random distribution. The two dominant damage mechanisms composites, plastic deformation interfacial debonding taken into account in simulation. Periodic boundary conditions applied representative elements....
A high performance nano-hybrid superabsorbent composite was prepared through the graft polymerization of acrylic acid into hydroxyethyl cellulose backbone chains in presence diatomite clay as an inorganic nano-filler.
O-GlcNAc transferase (OGT) plays an important role in regulating numerous cellular processes through reversible post-translational modification of nuclear and cytoplasmic proteins. However, the function O-GlcNAcylation is still not well understood. Cell permeable OGT inhibitors are needed to manipulate levels clarify regulatory mechanism this modification. Here, we report a specific natural-product inhibitor (L01), which was identified from structure-based virtual screening analysis. L01...
Microorganisms play essential roles in soil-ecosystem multifunctionality. However, the contribution of their community assembly processes, composition, diversity, and keystone species to ecosystem multifunctionality is unclear, especially tea-plantation ecosystems. In order assess effects various intercropping patterns (tea-plant monoculture tea plants, respectively, intercropped with soybean, soybean—milk vetch, soybean—red clover, soybean—smooth vetch) on soil rare abundant taxa, a field...
Gibberella stalk rot (GSR) by Fusarium graminearum causes significant losses of maize production worldwide. Jasmonates (JAs) have been broadly known in regulating defense against pathogens through the homeostasis active JAs and COI-JAZ-MYC function module. However, functions different molecular species module interactions with regulation diverse metabolites remain unknown. In this study, we found that exogenous application MeJA strongly enhanced resistance to GSR. RNA-seq analysis showed...
Recently, there has been growing interest in the use of natural available materials to prepare superabsorbents due their low-cost and environmental friendliness.