- Blood Pressure and Hypertension Studies
- Urinary Tract Infections Management
- Aortic aneurysm repair treatments
- Pelvic floor disorders treatments
- Aortic Disease and Treatment Approaches
- Acute Ischemic Stroke Management
- Hormonal Regulation and Hypertension
- Heart Rate Variability and Autonomic Control
- Multiple Sclerosis Research Studies
- Endometriosis Research and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Glioma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Advanced Glycation End Products research
- Cerebral Venous Sinus Thrombosis
- Ion Transport and Channel Regulation
- Myasthenia Gravis and Thymoma
- Cancer Mechanisms and Therapy
- Neuroinflammation and Neurodegeneration Mechanisms
- Lipid metabolism and disorders
- Intraoperative Neuromonitoring and Anesthetic Effects
- Monoclonal and Polyclonal Antibodies Research
- Long-Term Effects of COVID-19
- Eicosanoids and Hypertension Pharmacology
- Autoimmune and Inflammatory Disorders Research
Soochow University
2021-2025
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
2025
Sichuan University
2021-2024
West China Second University Hospital of Sichuan University
2021-2024
Capital Medical University
2017-2024
Beijing Anzhen Hospital
2017-2024
Suzhou Municipal Hospital
2022-2024
Nanjing Medical University
2022-2024
Shanxi Eye Hospital
2024
Guang’anmen Hospital
2021
Misdiagnosis of acute aortic dissection (AAD) can lead to significant morbidity and death. Soluble ST2 (sST2) is a cardiovascular injury-related biomarker. The extent which sST2 elevated in AAD whether discriminate from other causes sudden-onset severe chest pain are unknown.We measured plasma concentrations (R&D Systems assay) 1360 patients, including 1027 participants the retrospective discovery set 333 patients with initial suspicion enrolled prospective validation cohort. Measures...
Plasma ceramides (Cer) have been used to evaluate risk of cardiovascular (CV) events in patients with coronary heart disease. We investigated the performance and ceramide score (CERT) hypertensive at high CV risk.Seven were analyzed using ultra-performance liquid chromatography-tandem mass spectrometry 920 essential hypertension risk, who visited Beijing Anzhen Hospital from September 2016 2018 (median age: 49 years, 562 males). All followed up for major adverse (MACE), which included...
Abstract Nitro-fatty acids (NO 2 -FAs) are a class of bioactive lipids that mediate metabolic, anti-oxidative stress, anti-inflammatory, and other signaling actions. Endogenously, NO -FAs derived from the non-enzymatic reactions unsaturated fatty with reactive nitrogen species. The electrophilic properties nitro group results in being able to undergo rapid reversible biological nucleophiles, such as cysteine histidine, thus supporting post-translational modifications proteins. nucleophiles...
Worsening heart failure (WHF) is a heterogeneous clinical syndrome with poor prognosis. More effective risk stratification tools are required to identify high-risk patients. Evidence suggest that aberrant ceramide accumulation can be affected by factors and as driver of tissue damage. We hypothesized specific lengths ratios serve biomarkers for in WHF patients reflecting pathological changes distinct organ dysfunctions.We measured seven plasma ceramides using liquid chromatography-mass...
Patients with stroke due to large artery atherosclerosis are at risk of early progression and recurrence. The efficacy safety argatroban in patients who did not receive reperfusion therapy, which may benefit from it, uncertain.
Abstract Background: Xihuang pill has been widely applied as a promising adjunctive drug for gastric cance. However, the exact effects and safety of have yet to be systematically investigated. We aimed summarize effificacy treatment advanced GC through meta-analysis, in order provide scientific reference design future clinical trials. Methods: The protocol followed Preferred Reporting Items Systematic Reviews Meta-Analyses Protocols. Relevant randomized controlled trials were searched from...
Objective: Aortic dissection (AD) is characterized by an acute onset, rapid progress, and high mortality. Levels of soluble ST2 (sST2) on presentation are elevated in patients with AD, which can be used to discriminate AD from chest pain. sST2 concentrations were found highly heritable the general population. The aim this study was investigate associations variations ST2-related gene expression risk. Methods: This case-control involving a total 2,277 participants conducted, including 435...
Abstract Purpose: The outbreak of SARS-CoV-2 began in December and rapidly caused a pandemic. To investigate the significance lymphopenia for severity disease, this study was performed. Methods: 115 patients confirmed COVID-19 from tertiary hospital Changsha, China were enrolled. clinical, laboratory, treatment outcome data collected compared between with or not. Results: median age 42 years (1-75). 54 (47.0%) had on admission. In group lymphopenia, more hypertension (30.8% vs 10.0%,...