Ala Overcenco
A5074672455- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Global Health Care Issues
- Radioactivity and Radon Measurements
- Thermoregulation and physiological responses
- Health disparities and outcomes
- Atmospheric chemistry and aerosols
- Radiation Dose and Imaging
- Human Health and Disease
- Healthcare Systems and Public Health
- Nutritional Studies and Diet
- Tree-ring climate responses
- Climate variability and models
- Health Systems, Economic Evaluations, Quality of Life
- Optimism, Hope, and Well-being
- Risk Perception and Management
- Radioactive contamination and transfer
- Hydrology and Drought Analysis
Ministry of Health, Labour and Social Protection
2021-2024
Ministry of Education, Culture and Research
2024
Public Health Agency
2023
Nicolae Testemițanu State University of Medicine and Pharmacy
2022
Research Network (United States)
2021
National School of Public Health, Management and Professional Development
2016
BackgroundExposure to cold or hot temperatures is associated with premature deaths. We aimed evaluate the global, regional, and national mortality burden non-optimal ambient temperatures.MethodsIn this modelling study, we collected time-series data on from 750 locations in 43 countries five meta-predictors at a grid size of 0·5° × across globe. A three-stage analysis strategy was used. First, temperature–mortality association fitted for each location by use regression. Second, multivariate...
Background: Few studies have examined variation in the associations between heat waves and mortality an international context. Objectives: We aimed to systematically examine impacts of on with lag effects internationally. Methods: collected daily data temperature from 400 communities 18 countries/regions defined 12 types by combining community-specific mean ≥90th, 92.5th, 95th, 97.5th percentiles duration ≥2, 3, 4 d. used time-series analyses estimate wave–mortality relation over lags 0–10...
Background Heatwaves are a critical public health problem. There will be an increase in the frequency and severity of heatwaves under changing climate. However, evidence about impacts climate change on heatwave-related mortality at global scale is limited. Methods findings We collected historical daily time series mean temperature for all causes or nonexternal causes, periods ranging from January 1, 1984, to December 31, 2015, 412 communities within 20 countries/regions. estimated...
The evidence and method are limited for the associations between mortality temperature variability (TV) within or days.We developed a novel to calculate TV investigated TV-mortality using large multicountry data set.We collected daily from 372 locations in 12 countries/regions (Australia, Brazil, Canada, China, Japan, Moldova, South Korea, Spain, Taiwan, Thailand, United Kingdom, States). We calculated standard deviation of minimum maximum temperatures during exposure days. Two-stage...
Cardiovascular disease is the leading cause of death worldwide. Existing studies on association between temperatures and cardiovascular deaths have been limited in geographic zones generally considered associations with total rather than cause-specific deaths.We used unified data collection protocols within Multi-Country Multi-City Collaborative Network to assemble a database daily counts specific causes from 567 cities 27 countries across 5 continents overlapping periods ranging 1979 2019....
Abstract Epidemiological analyses of health risks associated with non-optimal temperature are traditionally based on ground observations from weather stations that offer limited spatial and temporal coverage. Climate reanalysis represents an alternative option provide complete spatio-temporal exposure coverage, yet to be systematically explored for their suitability in assessing temperature-related at a global scale. Here we the first comprehensive analysis over multiple regions assess most...
Older adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts projected increase with global warming, influence of population aging on these trends remains unclear. Here we show that at 1.5 °C, 2 3 °C heat-related mortality in 800 locations across 50 countries/areas will by 0.5%, 1.0%, 2.5%, respectively; among which 1 5 4 deaths can be attributed aging. Despite a decrease cold-related due progressive warming alone, mostly counteract this...
Various retrospective studies have reported on the increase of mortality risk due to higher diurnal temperature range (DTR). This study projects effect DTR future across 445 communities in 20 countries and regions.DTR-related was estimated basis historical daily time-series weather factors from Jan 1, 1985, Dec 31, 2015, with data for regions, Multi-Country Multi-City Collaborative Research Network. We obtained projected series associated four climate change scenarios, using representative...
Minimum mortality temperature (MMT) is an important indicator to assess the temperature-mortality association, indicating long-term adaptation local climate. Limited evidence about geographical variability of MMT available at a global scale.We collected data from 658 communities in 43 countries under different climates. We estimated associations derive for each community using Poisson regression with distributed lag nonlinear models. investigated variation by climatic zone mixed-effects...
BackgroundIncreased mortality risk is associated with short-term temperature variability. However, to our knowledge, there has been no comprehensive assessment of the variability-related burden worldwide. In this study, using data from MCC Collaborative Research Network, we first explored association between variability and across 43 countries or regions. Then, provide a more picture global variability, gridded resolution 0·5° × were used assess at global, regional, national levels....
BackgroundClimate change can directly impact temperature-related excess deaths and might subsequently the seasonal variation in mortality. In this study, we aimed to provide a systematic comprehensive assessment of potential future changes variation, or seasonality, mortality across different climate zones.MethodsIn modelling collected daily time series mean temperature (all causes non-external only) via Multi-Country Multi-City Collaborative (MCC) Research Network. These data were during...
Extreme temperatures contribute significantly to global mortality. While previous studies on temperature and stroke-specific outcomes presented conflicting results, these were predominantly limited single-city or single-country analyses. Their findings are difficult synthesize due variations in methodologies exposure definitions.
BackgroundExposure to cold spells is associated with mortality. However, little known about the global mortality burden of spells.MethodsA three-stage meta-analytical method was used estimate by means a time series dataset 1960 locations across 59 countries (or regions). First, we fitted location-specific, spell-related associations using quasi-Poisson regression distributed lag non-linear model period up 21 days. Second, built multivariate meta-regression between location-specific and seven...
Assessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on from 757 locations in 43 countries during 1979–2020. used a two-stage time series design assess all-cause mortality. The results were pooled at national, regional, global levels. observed consistent decrease risk of as normalized increases across globe. average increase comparing 10th 100th percentile was 13.03%...
Abstract The rising humid heat is regarded as a severe threat to human survivability, but the proper integration of into heat-health alerts still being explored. Using state-of-the-art epidemiological and climatological datasets, we examined association between multiple stress indicators (HSIs) daily mortality in 739 cities worldwide. Notable differences were observed long-term trends timing events detected by HSIs. Air temperature (Tair) predicts heat-related well with robust negative...
An increase in the global health burden of temperature was projected for 459 locations 28 countries worldwide under four representative concentration pathway scenarios until 2099. We determined that amount each 100 ppm CO2 concentrations is nearly constant, regardless climate scenarios. The overall average during 2010-2099 largest Canada (1.16 °C/100 ppm) and Finland (1.14 ppm), while it smallest Ireland (0.62 Argentina (0.63 ppm). In addition, 1 °C increase, excess mortality increased...
Although seasonal variations in mortality have been recognized for millennia, the role of temperature remains unclear. We aimed to assess variation and examine contribution temperature.
Studies have investigated the effects of heat and temperature variability (TV) on mortality. However, few assessed whether TV modifies heat-mortality association. Data daily mortality in warm season were collected from 717 locations across 36 countries. was calculated as standard deviation average same previous days' minimum maximum temperatures. We used location-specific quasi-Poisson regression models with an interaction term between cross-basis for mean quartiles to obtain associations...
BackgroundWildfire activity is an important source of tropospheric ozone (O3) pollution. However, no study to date has systematically examined the associations wildfire-related O3 exposure with mortality globally.MethodsWe did a multicountry two-stage time series analysis. From Multi-City Multi-Country (MCC) Collaborative Research Network, data on daily all-cause, cardiovascular, and respiratory deaths were obtained from 749 locations in 43 countries or areas, representing overlapping...
To examine the associations between characteristics of daily rainfall (intensity, duration, and frequency) all cause, cardiovascular, respiratory mortality.
Temperature variability (TV) is associated with increased mortality risk. However, it still unknown whether intra-day or inter-day TV has a higher effect. We aimed to assess the association of and all-cause, cardiovascular, respiratory mortality. collected data on total, meteorology from 758 locations in 47 countries regions 1972 2020. defined as standard deviation (SD) daily mean temperatures across lag interval, average SD minimum maximum each day. In first stage, TVs were modelled...