A5070767176- Glioma Diagnosis and Treatment
- Ubiquitin and proteasome pathways
- Ferroptosis and cancer prognosis
- Immune cells in cancer
- Occupational and environmental lung diseases
- Lung Cancer Diagnosis and Treatment
- Single-cell and spatial transcriptomics
- Vascular Malformations Diagnosis and Treatment
- interferon and immune responses
- Cerebral Venous Sinus Thrombosis
- Neurological Complications and Syndromes
- Parkinson's Disease Mechanisms and Treatments
- Pleural and Pulmonary Diseases
- Peripheral Neuropathies and Disorders
- Microtubule and mitosis dynamics
- Advanced MRI Techniques and Applications
- Brucella: diagnosis, epidemiology, treatment
- Ophthalmology and Eye Disorders
- Neurological disorders and treatments
- Immunotherapy and Immune Responses
- Multiple Sclerosis Research Studies
- RNA modifications and cancer
- Intracranial Aneurysms: Treatment and Complications
- Galectins and Cancer Biology
- MicroRNA in disease regulation
Ningxia Medical University
2024-2025
Shanxi Medical University
2022-2024
First Hospital of Shanxi Medical University
2022-2024
Ningxia Medical University General Hospital
2024
First Affiliated Hospital of Guangzhou Medical University
2015
Guangzhou Medical University
2015
The cell division cycle associated (CDCA) genes regulate the cycle; however, their relationship with prognosis in glioma has been poorly reported literature. Cancer Genome Atlas (TCGA) was utilized to probe CDCA family relation adverse clinical features of glioma. Glioma single-cell atlas reveals specific expression CDCA3, 4, 5, 8 malignant cells and CDCA7 neural progenitor (NPC)-like cells. data from TCGA, China Project (CGGA) gene omnibus (GEO) database all demonstrated that CDCA2, 3, 7...
Abstract Identifying the mechanism of glioma progression is critical for diagnosis and treatment. Although studies have shown that guanylate-binding protein 2(GBP2) has roles in various cancers, its function unclear. In this work, we demonstrate GBP2 high expression levels tissues. cells, depletion impairs proliferation migration, whereas overexpression enhances migration. Regarding mechanism, clarify epidermal growth factor receptor (EGFR) signaling regulated by GBP2, also interacts...
Abstract Background Human Deltex 2 (DTX2) is a ubiquitin E3 ligase that functions as an oncogene and has been shown to participate in many human cancers. However, the role of DTX2 glioma progression remained obscure. In this study, we explore mechanism underlying function progression. Methods The associations between expression clinical characteristics were determined by bioinformatic analysis data from Cancer Genome Atlas Protein Atlas. tissues was detected using immunohistochemistry...
Abstract Objectives To assess the value of tumor biomarkers in determination tumor‐related pleural effusion (PE). Cytological examination fluid has a limited sensitivity diagnosing PE. Methods Pleural and serum samples were obtained from 1137 patients PE etiology was determined by multiple diagnostic techniques. Carcinoembryonic antigen (CEA) levels measured both samples. Levels cancer (CA) 125, glucose, lactate dehydrogenase (LDH) assessed specimens. Results 601 diagnosed with tumors, while...
Guanylate binding protein 2 (GBP2) is a member of the guanine family, and its relationship with prognostic outcomes tumor immune microenvironments in glioma remains elusive. We found GBP2 were increased tissues at both mRNA levels. Kaplan-Meier curves revealed that high expression was linked worse survival patients, multivariate Cox regression analysis indicated an independent factor for glioma. Combined database significantly related to level infiltration immunomodulators. Single-cell...
Gliomas have a high incidence rate in central nervous tumors. Although many breakthroughs been made the pathogenesis and treatment of glioma, recurrence metastasis rates patients not improved based on uniqueness glioma. Glioma destroys surrounding basement membrane (BM), leading to local infiltration, resulting corresponding clinical neurological symptoms. Therefore, exploring biological roles played by BM associated genes glioma is particularly necessary for comprehensive understanding...
Abstract Aim： In this study, we thoroughly examine and discuss the clinical features, laboratory findings, treatment, recovery of 38 neurobrucellosis cases. Additionally, provide insights into most recent research advances in field neurobrucellosis. Materials methods ：In collected general data, characteristics, ancillary tests, treatment plans cases diagnosed treated at General Hospital Ningxia Medical University from March 2012 to December 2022. Results： Among cases, 25 were male, 23 had a...
The mechanism by which ubiquitin‑specific protease 18 (USP18) (enzyme commission: 3.4.19.12) inhibition in cancer promotes cell pyroptosis via the induction of interferon (IFN)‑stimulated genes has been recently demonstrated. It is also known that USP18 influences epithelial‑mesenchymal transition glioma cells. In present study, upregulation was revealed through bulk transcriptome analysis, associated with poor prognosis patients glioma. Furthermore, levels affected response to immunotherapy...
Rationale: Anti-Myelin oligodendrocyte glycoprotein (MOG) and anti-metabotropic glutamate receptor 5 (mGluR5) double antibody positive encephalitis characterized by optic neuritis is extremely rare. We present a case of overlapping syndrome MOG-IgG-associated disease anti-mGluR5 manifested as neuritis. Patient concerns: A 60-year-old Chinses woman presented to the hospital with progressive vision loss headache for 1 week. The cerebrospinal fluid examination was within normal range. Visual...