A5090581016- Renal and related cancers
- Renal cell carcinoma treatment
- Chaos control and synchronization
- Ferroptosis and cancer prognosis
- Industrial Technology and Control Systems
- Nonlinear Dynamics and Pattern Formation
- Ion Transport and Channel Regulation
- Cancer Genomics and Diagnostics
- Electrolyte and hormonal disorders
- Complex Systems and Time Series Analysis
- RNA modifications and cancer
- Autophagy in Disease and Therapy
- CRISPR and Genetic Engineering
Fujian Medical University
2018-2024
Sanming University
2018
Hebei GEO University
2011
BackgroundUncoordinated 51-like kinase 1 (ULK1) plays a vital role in autophagy. ULK1 dysregulation has recently been found several human cancers.MethodsmRNA expression levels of and clinical information were analysed from The Cancer Genome Atlas data. verified 36 paired fresh ccRCC tissue specimens by western blot analysis. Expression was knockdown shRNA lentivirus. activity inhibited SBI-0206965. effect inhibition measured detecting the apoptotic rate, autophagy, ratio ROS NADPH. efficacy...
Background: Epithelial sodium channels are disputed in renal cell carcinoma, but its functions and effects on clinical outcomes not well understood.Materials Methods: IHC PT-PCR were used to detect ENaCα, β, γ, AVPR2, AQP2, MR expression the primary tumor peritumoral tissues.GEPIA online tool was analyze relationship between epithelial clinical-pathological characteristics.Tumor IMmune Estimation Resource investigate immune profile relevant expression.Results: Quantitative RT-PCR analysis...
Objectives. The most common subtype of renal cell carcinoma, clear carcinoma (ccRCC), has a high heterogeneity and aggressive nature. basement membrane (BM) is known to play vital role in tumor metastasis. BM-related genes remain untested ccRCC, however, terms their prognostic significance. Methods. were gleaned from the recent cutting-edge research. RNA-seq clinical data ccRCC obtained TCGA GEO databases, respectively. multigene signature was constructed using univariate Cox regression...
We study a nonlinear discrete dynamic game model of an oligopoly market. In order to competition process the players, paper considers Bertrand with bounded rationality. A four oligopolies is modeled by four-dimensional difference equation set. The stability equilibrium point are discussed. demonstrate rich dynamical behaviors system. chaotic features justified numerically via bifurcation diagrams, maximal Lyapunov exponents and system's sensitive dependence on initial conditions. It...