A5102983094- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Neuroscience and Neuropharmacology Research
- Neonatal and fetal brain pathology
- Cardiac electrophysiology and arrhythmias
- ECG Monitoring and Analysis
- Atomic and Subatomic Physics Research
- Glioma Diagnosis and Treatment
- Sleep and Wakefulness Research
- Pharmacological Effects and Toxicity Studies
- Wound Healing and Treatments
- Functional Brain Connectivity Studies
- Mesenchymal stem cell research
- Advanced MRI Techniques and Applications
- Reconstructive Surgery and Microvascular Techniques
Beijing Haidian Hospital
2013-2025
Capital Medical University
2020
High frequency oscillations (HFOs) are considered as biomarker for epileptogenicity. Reliable automation of HFOs detection is necessary rapid and objective analysis, determined by accurate computation the baseline. Although most existing automated detectors measure baseline accurately in channels with rare HFOs, they lose accuracy frequent HFOs. Here, we proposed a novel algorithm using maximum distributed peak points method to improve determination wide activity ranges calculate dynamic...
ABSTRACT Importance Perampanel (PER) is used less extensively in children than adults. Currently, there a lack of data from PER clinical studies with large sample sizes Chinese and adolescents epilepsy, especially those refractory epilepsy. Objective To evaluate the effectiveness, retention, safety treatment epilepsy China. Methods This was multicenter, prospective, observational study. Children who received as adjunctive therapy were included. The primary effectiveness endpoint proportion...
Abstract Objective Altered functional activities and hypometabolism have been found in medial temporal lobe epilepsy patients with hippocampal sclerosis (mTLE‐HS). Hybrid PET/MR scanners provide opportunities to explore the relationship between resting‐state energy consumption activities, but whether repeated seizures disturb bioenergetic coupling its seizure outcomes remain unknown. Methods 18 F‐FDG PET MRI (rs‐fMRI) scans were performed hybrid 26 mTLE‐HS healthy controls. Energy was...
High frequency oscillations (HFOs) has been proposed as a promising biomarker of the epileptogenic zone (EZ). But accurate delineation EZ based on HFOs is still challenging. Our study compared from and non-EZ their associations with interictal slow waves, aiming at exploring new way to localize EZ. Nineteen medically intractable epilepsy patients good surgical outcome were included. Five-minute intracranial EEG epochs wave sleep randomly selected, then ripples (80-200 Hz), fast (200-500 Hz)...
Accurately identifying epileptogenic zone (EZ) using high-frequency oscillations (HFOs) is a challenge that must be mastered to transfer HFOs into clinical use. We analyzed the ability of convolutional neural network (CNN) model distinguish EZ and non-EZ HFOs. Nineteen medically intractable epilepsy patients with good surgical outcomes 2 years after surgery were studied. Five-minute interictal intracranial electroencephalogram epochs slow-wave sleep selected randomly. Then 5 s segments...
Objective To investigate the characteristics of insular seizures and surgical strategies,and to observe efficacy treatment.Methods Preoperative evaluation results seven patients with epilepsy were analyzed.Symptomatic characteristics,MRI,scalp video-EEG,and localization value EEG examination intracranial electrode summarized.Engel standards applied grade postoperative effects.Patients followed after operation.Results In patients,lesions three cases on left four right.Their symptoms mainly as...
Objective To explore the pathological factors that affect anatomical correlation between epilepsy onset zone(EOZ) and abnormal cerebral area (ACA).Methods Three-hundred fifty-eight cases were retrospectively analyzed in department of functional neurology neurosurgery Beijing Haidian Hospital November 2007 2009,22 who with due to lesion had underwent EOZ and/or ACA resection after comprehensive evaluations MRI,Scalp-EEG intracranial-EEG monitoring.The was defined as overlapping (＜ 5...
Objective To explore the clinical characteristics and epileptic discharge propagation of patients with insular lobe epilepsy.Methods retrospectively analyze ictal symptoms,scalp EEG ECoG 7 patients,who were confirmed attack originated in or operculum by a variety evaluation methods,such as medical history,imaging,scalp intracranial EEG.Results 101 episodes recorded patients.3 cases had seizures that from mesiolateral emporal regions scalp monitoring.5 was monitored both scale ECoG.The...
Objective: To investigate the design of specialized protective cap for patients with alopecia after autologous hair transplantation and its application value in nursing care transplantation. Methods: The author designed a kind elastic gauze, fiber, silica gel, other materials. It was divided into two parts, front piece mainly used to protect receiving site, back pressure hemostasis at donor site. From February 2017 January 2019, 81 had First Affiliated Hospital Air Force Military Medical...