Xiaonan Li

ORCID: 0000-0001-7037-193X
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About
Contact & Profiles
Research Areas
  • Neuroscience and Neuropharmacology Research
  • Neurobiology and Insect Physiology Research
  • Insect and Arachnid Ecology and Behavior
  • Neurotransmitter Receptor Influence on Behavior
  • Oxidative Organic Chemistry Reactions
  • Catalytic C–H Functionalization Methods
  • Synthesis and Catalytic Reactions
  • Nicotinic Acetylcholine Receptors Study
  • Epilepsy research and treatment
  • Advanced Neuroimaging Techniques and Applications
  • Psychological Well-being and Life Satisfaction
  • Animal Behavior and Reproduction
  • Neonatal and fetal brain pathology
  • Neuroendocrine regulation and behavior
  • Anesthesia and Neurotoxicity Research
  • Receptor Mechanisms and Signaling
  • Dietary Effects on Health
  • Immune cells in cancer
  • Lipid Membrane Structure and Behavior
  • Pediatric Pain Management Techniques
  • Fiber-reinforced polymer composites
  • Advanced battery technologies research
  • Tryptophan and brain disorders
  • Hearing Loss and Rehabilitation
  • Neural dynamics and brain function

Huazhong University of Science and Technology Hospital
2025

Chinese Academy of Sciences
2011-2023

University of Chinese Academy of Sciences
2011-2023

Second Affiliated Hospital of Nanjing Medical University
2020-2023

Institute of Biophysics
2020-2023

Anhui University of Science and Technology
2022

Capital Medical University
2017-2021

Institute of Psychology, Chinese Academy of Sciences
2021

Guangzhou Regenerative Medicine and Health Guangdong Laboratory
2021

Shanghai Institute of Organic Chemistry
2019-2020

The prevalence of mental health problems among college students, both domestically and internationally, has emerged as a significant public concern. College students are in period transition to independent living. Adopting healthy lifestyle can have advantageous effects on their overall well-being. Thus, this study aimed investigate the impact choices China. We conducted cross-sectional online survey from 2021 2023 at university Wuhan (N = 1826) using cluster sampling method. employed...

10.1186/s12889-025-21482-4 article EN cc-by-nc-nd BMC Public Health 2025-01-21

The first Pd-catalyzed enantioselective azidation of unactivated alkenes has been established by using readily accessible 1-azido-1,2-benziodoxol-3(1H)-one (ABX) as an azidating reagent, which affords a wide variety structurally diverse 3-N3 -substituted piperidines in good yields with excellent enantioselectivity. reaction features functional-group compatibility and mild conditions. Notably, both electrophilic reagent the sterically bulky chiral pyridinyl-oxazoline (Pyox) ligand are crucial...

10.1002/anie.202006757 article EN Angewandte Chemie International Edition 2020-06-10

Increasing pollution of heavy metals poses great risks to animals globally. Their survival likely relies on an ability detect and avoid harmful metal ions (HMIs). Currently, little is known about the neural mechanisms HMI detection. Here, we show that Drosophila related species Drosophilidae actively toxic HMIs at micromolar concentrations. The high sensitivity biologically relevant. Particularly, their cadmium as most bitter substance, denatonium. Detection in food requires Gr66a+ gustatory...

10.1016/j.isci.2023.106607 article EN cc-by iScience 2023-04-07

Sociality is among the most important motivators of human behaviour. However, neural mechanisms determining levels sociality are largely unknown, primarily due to a lack suitable animal models. Here, we report presence surprising degree general in Drosophila. A newly-developed paradigm study social approach behaviour flies reveal that cues perceive through both vision and olfaction converged central brain region, γ lobe mushroom body, which exhibite activation response experience. The...

10.1038/s41467-020-19102-3 article EN cc-by Nature Communications 2020-10-22

High frequency oscillations (HFOs) are considered as biomarker for epileptogenicity. Reliable automation of HFOs detection is necessary rapid and objective analysis, determined by accurate computation the baseline. Although most existing automated detectors measure baseline accurately in channels with rare HFOs, they lose accuracy frequent HFOs. Here, we proposed a novel algorithm using maximum distributed peak points method to improve determination wide activity ranges calculate dynamic...

10.1142/s0129065717500290 article EN International Journal of Neural Systems 2017-04-17

Musical training is thought to be related improved language skills, for example, understanding speech in background noise. Although studies have found that musicians and nonmusicians differed morphology of bilateral arcuate fasciculus (AF), none has associated such white matter features with speech-in-noise (SIN) perception. Here, we tested both SIN the diffusivity AF segments using diffusion tensor imaging. Compared nonmusicians, had higher fractional anisotropy (FA) right direct lower...

10.1093/cercor/bhab063 article EN cc-by Cerebral Cortex 2021-02-26

Preterm infants in neonatal intensive care units are inevitably subjected to numerous painful procedures. However, little is known about the consequences of early pain experience on fear memory formation later life. We hypothesized that exposure repetitive life triggered hippocampal synaptic plasticity and resulted deficiency prepubertal adult rats. From day birth (P0) postnatal 7 (P7), male rat pups were randomly assigned either needle pricks or tactile touches repetitively every 6 hours....

10.3389/fnins.2020.00722 article EN cc-by Frontiers in Neuroscience 2020-07-08

The courtship ritual is a dynamic interplay between males and females. Courtship successfully leading to copulation determined by the intention of both parties which conveyed complex action sequences. In Drosophila, neural mechanisms controlling female's willingness mate, or sexual receptivity, have only recently become focus investigations. Here, we report that pre-mating receptivity in females requires activity within subset serotonergic projection neurons (SPNs), positively regulate...

10.1016/j.isci.2023.106123 article EN cc-by-nc-nd iScience 2023-02-02

Abstract The first Pd‐catalyzed enantioselective azidation of unactivated alkenes has been established by using readily accessible 1‐azido‐1,2‐benziodoxol‐3(1 H )‐one (ABX) as an azidating reagent, which affords a wide variety structurally diverse 3‐N 3 ‐substituted piperidines in good yields with excellent enantioselectivity. reaction features functional‐group compatibility and mild conditions. Notably, both electrophilic reagent the sterically bulky chiral pyridinyl‐oxazoline (Pyox) ligand...

10.1002/ange.202006757 article EN Angewandte Chemie 2020-06-10

Epilepsy is a network disease caused by aberrant neocortical large-scale connectivity spanning regions on the scale of several centimeters. High-frequency oscillations, characterized 80-600 Hz signals in electroencephalography, have been proven to be promising biomarker epilepsy that can used assessing severity and susceptibility as well location epileptogenic zone. However, presence high-frequency oscillation remains topic debate oscillations previously thought incapable propagation,...

10.2174/1570159x19666210908165641 article EN Current Neuropharmacology 2021-09-10

A hardware system for a laboratory-built desktop nuclear magnetic resonance (NMR) spectrometer was constructed with module design based on single-phase detection architecture. This features an operating frequency of DC to 100 MHz, RF pulse power 0.7244 mW 1.2589 W, minimum detectable signal 1.5136 × 10−10 mW, and receiver bandwidth 20 kHz. Verification the functional feasibility NMR implemented using 30-mL custom probe in 0.23-T field. baseband free induction decay also acquired through...

10.1080/10739149.2010.537717 article EN Instrumentation Science & Technology 2011-01-31

ObjectiveReal-time monitoring of cytokine secretion at the single immunocyte level, based on concept immune cells, sociology has been recently reported. However, relationships between gl...

10.18679/cn11-6030/r.2016.018 article EN Translational Neuroscience and Clinics 2016-01-01

Innovative treatments of refractory epilepsy are widely desired, for which chemogenetic technology can provide region- and cell-type-specific modulation with relative noninvasiveness.

10.2174/1570159x22999240131122455 article EN Current Neuropharmacology 2024-02-09

<title>Abstract</title> Dopamine release plays an important role in regulating neuronal behaviors behind drug addiction and abuse. Plant alkaloids nicotine salts administrations have been reported to exert significant effects on dopamine human animal brains. However, vivo detection of the brain is challenging mostly invasive, which greatly limit its wide application study drug-induced neurological mechanisms. A novel <sup>18</sup>F- Fallypride positron emission tomography (PET) imaging...

10.21203/rs.3.rs-4494554/v1 preprint EN cc-by Research Square (Research Square) 2024-06-18

When the power converter connected to high-frequency transformer breaks through bottleneck and reaches a frequency of 100kHz or even higher, transformer's inter-turn insulation faces more serious discharge high temperature problems. In order improve service performance oil-immersed paper, composite K-BNNSs particles are prepared by ultrasonic stripping, heat treatment thermomagnetic stirring. Then, mixed with PMIA slurry produce aramid paper. And effects different contents on thermal...

10.20944/preprints202410.2459.v1 preprint EN 2024-10-31

Interleukin-1β (IL-1β) is an important proinflammatory cytokine that plays a key role in injuries and diseases of the central nervous system (CNS). The voltage-gated Na(+) channel most ion neurons, essential for regenerative action potential (AP). also contributes to many brain. However, relations between IL-1β channels remain unreported. In this study, whole cell patch-clamp recording was used investigate acute effects (10 ng/mL) on voltage-dependent currents AP cultured cortical neurons...

10.3724/sp.j.1141.2011.03323 article EN Zoological Research 2011-06-01

Rates of overweight and obesity continue to grow in adolescents. Overweight adolescence are associated with numerous immediate long-term adverse health conditions. Throughout adolescence, parents the family have an important central influence on adolescents' lifestyle. The home environment may be a major factor shaping children's weight. However, our current understanding interplay between family-related variables adolescents or is limited fragmented. This study aimed assess relationship who...

10.3389/fped.2023.1282117 article EN cc-by Frontiers in Pediatrics 2023-10-25

Event Abstract Back to White matter tract of orthographic recognition and its functional plasticity: Evidence from patients congenital blinds Ke Wang1, Xiaonan Li1, Ruiwang Huang2, Junhua Ding1, Luping Song3 Zaizhu Han1* 1 Beijing Normal University, State Key Laboratory Cognitive Neuroscience Learning, China 2 South School Psychology, 3 Rehabilitation Hospital, Capital Medical College Research Center, Orthographic recognition, a pivotal stage during word reading, has been found be supported...

10.3389/conf.fnhum.2018.228.00055 article EN cc-by Frontiers in Human Neuroscience 2018-01-01

10.11852/zgetbjzz2018-1170 article EN Chinese Journal of Child Health Care 2018-12-10
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