A5034952482- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Pediatric health and respiratory diseases
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- COVID-19 and healthcare impacts
Amphia Ziekenhuis
2019-2023
Maintenance treatment with macrolide antibiotics has shown to be effective in reducing exacerbations COPD patients. A major concern prolonged is the development of bacterial resistance. In this study we determined effect azithromycin on and acquisition resistance macrolides nasopharyngeal flora
Abstract: Macrolides are effective in reducing the number of exacerbations COPD patients with frequent exacerbator phenotype. Our study did not show a persistent effect azithromycin on exacerbation frequencies after more than one year usage. Keywords: Macrolide, long-term, exacerbations, COPD, COLUMBUS
Abstract ObjectivesMaintenance treatment with macrolide antibiotics has shown to be effective in reducing exacerbations COPD patients. A major concern prolonged is the development of bacterial resistance. In this study we determined effect azithromycin on and acquisition resistance macrolides nasopharyngeal flora patients.MethodsThis was part COLUMBUS trial, a randomised, double-blind, placebo-controlled trial measure maintenance 92 patients exacerbation rates during 12-month period. order...
<b>Introduction:</b> Azithromycin maintenance therapy during one year resulted in a significant lower number of exacerbations as has been shown the Columbus study. The aim our current study is to investigate whether azithromycin treatment given for more than equal effective reducing exacerbation frequency. <b>Method:</b> This was retrospective cohort using data from Trial (N=92). In this we compared patients still receiving macrolide after finishing trial with who stopped treatment....
<b>Objectives:</b> A major concern with prolonged treatment antibiotics is the development of bacterial resistance. In this study we determined effect azithromycin on and acquisition resistance to macrolides in nasopharyngeal flora COPD patients. <b>Methods:</b> This was part COLUMBUS trial, a randomised, double-blind, placebo-controlled trial measure maintenance 92 patients exacerbation rates during 12-month period. order determine macrolides, used targeted metagenomic approach presence...
Abstract Objectives : Maintenance treatment with macrolide antibiotics has shown to be effective in reducing exacerbations COPD patients. A major concern prolonged is the development of bacterial resistance. In this study we determined effect azithromycin on and acquisition resistance macrolides nasopharyngeal flora Methods This was part COLUMBUS trial, a randomised, double-blind, placebo-controlled trial measure maintenance 92 patients exacerbation rates during 12-month period. order...