A5016431575- Additive Manufacturing and 3D Printing Technologies
- Advanced Surface Polishing Techniques
- Manufacturing Process and Optimization
- Advanced machining processes and optimization
- Additive Manufacturing Materials and Processes
- Electrospun Nanofibers in Biomedical Applications
- Injection Molding Process and Properties
- Advancements in Transdermal Drug Delivery
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Advanced Machining and Optimization Techniques
- Dermatology and Skin Diseases
- Luminescence Properties of Advanced Materials
- High Entropy Alloys Studies
- Welding Techniques and Residual Stresses
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Tissue Engineering and Regenerative Medicine
- Silk-based biomaterials and applications
- Infection Control in Healthcare
- Adhesion, Friction, and Surface Interactions
- Advanced Measurement and Metrology Techniques
- Pigment Synthesis and Properties
- Assembly Line Balancing Optimization
- Toxin Mechanisms and Immunotoxins
University of Nottingham
2014-2024
This paper presents a new approach for chatter modelling in micro-milling. The model takes into account: the nonlinearity of uncut chip thickness including run-out effect; velocity dependent micro-milling cutting forces; dynamics tool-holder-spindle assembly. is determined after considering full kinematics tool effect. forces are by: (i) finite element (FE) prediction orthogonal at different velocities and thicknesses; (ii) describing relationship between forces, thicknesses nonlinear...
Material extrusion additive manufacturing is widely used for porous scaffolds in which polymer filaments are extruded the form of log-pile structures. These structures typically designed with assumption that have a continuous cylindrical profile. However, as filament extruded, it interacts previously printed (e.g. on lower 3D layers) and its geometry varies from form. No models currently exist can predict this critical variation, impacts geometry, pore size mechanical properties. Therefore,...
Electrospinning is a common technique used to fabricate fibrous scaffolds for tissue engineering applications. There now growing interest in assessing the ability of collector plate design influence patterning fibres during electrospinning process. In this study, we investigate novel method generate hybrid electrospun consisting both random and defined three-dimensional (3D) micro-topography at surface, using patterned resin formers produced by rapid prototyping (RP)....
Basal cell carcinoma (BCC) is the most common cutaneous malignancy in humans. One of efficacious drugs used management BCC immunomodulator, imiquimod. However, imiquimod has physiochemical properties that limit its permeation to reach deeper, nodular tumor lesions. The use microneedles may overcome such limitations and promote intradermal drug delivery. current work evaluates effectiveness using an oscillating microneedle device Dermapen either as a pre- or post-treatment with 5% w/w cream...
3D printing is of great interest for tissue engineering scaffolds due to the ability form complex geometries and control internal structures, including porosity pore size. The porous structure plays an important role in cell ingrowth nutrition infusion. Although size printed have been frequently studied, surface size, which are critical infiltration mass transport, not investigated. geometry can differ considerably from scaffold depending on process. It vital be able as well fabricate...
The aim of this study was to design and manufacture an easily assembled cartilage implant model for auricular reconstruction. First, the printing accuracy mechanical properties 3D-printed poly-ε-caprolactone (PCL) scaffolds with varying porosities were determined assess overall material properties. Next, applicability alginate as cell carrier determined. Using optimal outcomes both experiments (in terms (bio)mechanical properties, survival, neocartilage formation, accuracy), a hybrid...
Projection-microstereolithography is an additive manufacturing technique based on the spatially controlled solidification of a liquid photopolymer exposure to digitally manipulated light patterns. This study presents methodology evaluate effect type-I photoinitiator reaction kinetics in process and cytocompatibility produced components. While speed degree conversion were heavily dependent applied amount initiator, clear toxic was observed with all tested concentrations, post-processing step...
Electrospun fibrous materials have increasing applications in regenerative medicine due to the similarity of fibre constructs morphology certain extracellular matrices. Although experimentally electrospinning method is relatively simple, at theoretical level interactions between process parameters and their influence on not yet fully understood. Here, we hypothesised that a design experiments (DoE) model could determine combinations result significant effects poly-D,L-lactic acid (PDLLA)...
With the rising use of umbilical cord blood (UCB) as an alternative source hematopoietic stem cells, storage inventories UCB have grown, giving rise to genetically diverse globally. In absence reliable markers such CD34 or counts colony-forming units, total nucleated cell (TNC) are often used indicator potency, and transplant centers worldwide select units with largest TNC. As a result, banks driven increase quality stored by increasing TNC count products stored. However, these face...
This paper introduces a non-assembly manufacturing case with microstereolithography technology. The design and process of pneumatic thrust bearing is described, special tessellation method developed to further improve the capability system thus bigger products can also be easily manufactured. Implemented in layer-by-Iayer fashion, stereolithography has been used for rapid complex devices, it avoids expensive assembly traditional manufacturing. presents that produce high-resolution intricate...