Leyi Liu

ORCID: 0000-0002-7258-037X
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About
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Research Areas
  • MicroRNA in disease regulation
  • Graphene and Nanomaterials Applications
  • RNA Interference and Gene Delivery
  • Circular RNAs in diseases
  • Cancer-related molecular mechanisms research
  • Advanced Nanomaterials in Catalysis
  • Advanced Technology in Applications
  • Wound Healing and Treatments
  • MXene and MAX Phase Materials
  • Remote Sensing and Land Use
  • Educational and Technological Research
  • Power Systems and Technologies
  • Tree Root and Stability Studies
  • Nerve injury and regeneration
  • Remote Sensing and LiDAR Applications
  • Light effects on plants
  • Plant responses to elevated CO2
  • Leaf Properties and Growth Measurement
  • Archaeological Research and Protection
  • Nanoplatforms for cancer theranostics
  • Plant Stress Responses and Tolerance
  • Nanoparticles: synthesis and applications
  • Renal and related cancers
  • Forest ecology and management
  • Renal cell carcinoma treatment

Shenzhen Stock Exchange
2024

Second Hospital of Tianjin Medical University
2020-2024

Tianjin Medical University
2020-2024

State Key Laboratory of Genetic Engineering
2023

Fudan University
2023

Southwest Forestry University
2020-2022

Honghu Hospital of Traditional Chinese Medicine
2021

Light and temperature are two key environmental signals that share several molecular components that, in turn, regulate plant growth. Darkness high ambient temperatures promote skoto- thermomorphogenesis, including stem elongation. Heat shock proteins 90 (HSP90s) facilitate the adaptation of organisms to various adverse stimuli. Here, we showed HSP90s required for hypocotyl elongation during both thermomorphogenesis. When activities impaired by knockdown expression or application HSP90...

10.1111/nph.18776 article EN New Phytologist 2023-01-28

Along with the increasing production and application of graphene oxide (GO), its environmental health safety (EHS) risks have become a global concern. Numerous studies investigated biosafety toxicity mechanisms associated GO, however, majority previous were based on direct toxic dose, which could not reflect realistic state exposure GO an indirect dose (low dose). Meanwhile, effects low-dose progression tumors are still unclearly. Herein, we found that can promote multiple types tumor cell...

10.1016/j.envpol.2023.121817 article EN cc-by-nc-nd Environmental Pollution 2023-05-12

Propofol is a common intravenous anesthetic that exerts an antitumor role in human cancers. Circular RNAs (circRNAs) play crucial roles the progression of various However, relationship between propofol and circRNA decaprenyl diphosphate synthase subunit 1 (circPDSS1) gastric cancer (GC) remains unclear.Cell proliferation was evaluated by Cell Counting Kit-8 (CCK-8), colony formation, 5-ethynyl-2'-deoxyuridine (EdU) assays. migration invasion were assessed transwell assay. apoptosis...

10.2147/cmar.s312989 article EN cc-by-nc Cancer Management and Research 2021-08-01

The Montgomery equation predicts leaf area as the product of length and width multiplied by a correction factor. It has been demonstrated to apply variety shapes. However, it is unknown whether tree size (measured diameter at breast height) affects shape size, or such variations in can invalidate calculating area. Here, we examined 60 individual trees alpine oak ( Quercus pannosa ) two growth patterns (trees growing from seeds vs. roots), with 30 individuals for each site. Between 100 110...

10.3389/fpls.2022.850203 article EN cc-by Frontiers in Plant Science 2022-06-09

Previous data have shown the prominent clinical efficacy of gefitinib in non-small cell lung cancer (NSCLC) patients. However, its therapeutic is limited because development resistance. This research designed to investigate role circRNA SET domain containing 3, actin histidine (circ_SETD3) sensitivity NSCLC gefitinib. The expression circ_SETD3, microRNA-873-5p (miR-873-5p) and amyloid protein-binding protein 2 (APPBP2) was detected by qRT-PCR. Protein determined western blot analysis or...

10.1080/1120009x.2021.2009991 article EN Journal of Chemotherapy 2021-12-03

Multilocular cystic renal neoplasm of low malignant potential (MCRNLMP) might be benefited from nephron-sparing surgery. Contrast-enhanced computed tomography is used for the diagnosis MCRNLMP but contrast-enhanced ultrasound has lack nephrotoxicity and several advantages over magnetic resonance. The purpose study was to compare diagnostic parameters preoperative against detection in patients who faced curative surgery complex mass.Data regarding ultrasound, tomography, clinicopathological...

10.1097/md.0000000000023110 article EN cc-by-nc Medicine 2020-11-10

Cultural landscapes are cultural property and they an illustration of the evolution human society living environment over time. As landscape is being valued more more, use 3D modeling becoming important. for reconstruction technology, most current methods complicated in terms network construction, use, storage, then affect efficiency subsequent heritage. To obtain technology with high efficiency, this paper combines circumferential binary feature extraction algorithm cloud computing proposes...

10.3233/jifs-179995 article EN Journal of Intelligent & Fuzzy Systems 2020-07-10

Abstract Background Prostate cancer (PCa) has a high incidence in men worldwide, and almost all PCa patients progress to the androgen-independent stage which lacks effective treatment measures. PTENP1, long non-coding RNA, been shown suppress tumor growth through rescuing of PTEN expression via competitive endogenous RNA (ceRNA) mechanism. However, PTENP1 was limited be applied for reason rapid enzymatic degradation, poor intracellular uptake, excessively base sequence synthesized....

10.21203/rs.3.rs-3844285/v1 preprint EN cc-by Research Square (Research Square) 2024-01-10

Prostate cancer (PCa) has a high incidence in men worldwide, and almost all PCa patients progress to the androgen-independent stage which lacks effective treatment measures. PTENP1, long non-coding RNA, been shown suppress tumor growth through rescuing of PTEN expression via competitive endogenous RNA (ceRNA) mechanism. However, PTENP1 was limited be applied for reason rapid enzymatic degradation, poor intracellular uptake, excessively base sequence synthesized. Considering unique advantages...

10.1186/s12951-024-02659-2 article EN cc-by Journal of Nanobiotechnology 2024-07-04

In the context of large-scale new power system access, scale dispatch automation is expanding, and it becomes extremely challenging for operation maintenance workers to achieve efficient accurate matching between fault descriptions contingency plans in face a large amount complicated data. order solve this problem speed up handling process, paper proposes profile algorithm systems based on language model low-rank adaptive fine-tuning. The method reduces consumption memory explicit training...

10.1109/acpee60788.2024.10532664 article EN 2022 7th Asia Conference on Power and Electrical Engineering (ACPEE) 2024-04-11

Peripheral nerve injury (PNI) is a relatively common disease caused by various circumstances, ultimately affecting the life quality of patients. Although existing medications and surgical interventions have particular benefits for repair, more effective therapeutic strategies are urgently needed types injuries. Increasing investigations nanomaterials demonstrated their excellent biological properties, such as biocompatibility, permeability, degradability, high medicine loading efficacy,...

10.1155/2022/7619884 article EN cc-by Journal of Nanomaterials 2022-01-01

Graphene oxide (GO) has been widely studied and applied in numerous industrial fields biomedical for its excellent physical chemical properties. Along with the production applications of GO persist increasing, environmental health safety risk (EHS) studied. However, previous studies almost focused on biotoxicity pristine under a relatively high exposure dose, without considering transformation process within biological mediums. Meanwhile, secondary toxicity or synergistic effects have not...

10.2139/ssrn.4028975 article EN SSRN Electronic Journal 2022-01-01
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