A5087371121- Olfactory and Sensory Function Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Genomics, phytochemicals, and oxidative stress
- Biochemical Analysis and Sensing Techniques
- Phytochemicals and Antioxidant Activities
- Caveolin-1 and cellular processes
- Galectins and Cancer Biology
- Spinal Cord Injury Research
- Drug-Induced Hepatotoxicity and Protection
- Nitric Oxide and Endothelin Effects
- Protein Kinase Regulation and GTPase Signaling
- Natural product bioactivities and synthesis
- Cytokine Signaling Pathways and Interactions
- Neurobiology and Insect Physiology Research
- Pharmacological Effects of Natural Compounds
- Bone and Dental Protein Studies
- Cell Adhesion Molecules Research
- Protein Tyrosine Phosphatases
- Seaweed-derived Bioactive Compounds
- Retinal Development and Disorders
- Erythrocyte Function and Pathophysiology
- NF-κB Signaling Pathways
- Ocular Diseases and Behçet’s Syndrome
- Aquaculture disease management and microbiota
- Food Quality and Safety Studies
Sangji University
2006-2025
Chungnam National University
2025
Gyeongsang National University
2023
Seoul National University
2023
Jeju National University
2012-2021
Chonnam National University
2020
Astex Pharmaceuticals
2019
Jeonbuk Agricultural Research & Extension Services
2013
Nation University
2010
National University
2004-2008
Hepatocellular carcinoma (HCC) has a poor prognosis and low survival rate. Drugs without side effects are desperately needed since chemotherapy negative effect on the host cells. Previous research firmly established that plant-based compounds have significant bioactivities impact host. Flavonoids, in particular, class of with both anti-inflammatory anti-cancer properties. Prunetrin (PUR) is glycosyloxyisoflavone (Prunetin 4'-O-glucoside) derived from Prunus sp., its other form, called...
Experimental autoimmune encephalomyelitis (EAE) in Lewis rats is an acute monophasic paralytic central nervous system disease, which most spontaneously recover from paralysis.EAE induced by encephalitogenic antigens, including myelin basic protein.EAE mediated CD4 + Th1 cells, secrete pro-inflammatory mediators, and spontaneous recovery regulatory T cells.Recently, it was established that classically activated macrophages (M1 phenotype) play important role the initiation of EAE, while...
Dermatitis is an inflammatory condition of the outer layer skin that causes itching, blisters, redness, swelling, and often exudation, scabs, peeling. Among them, purulent inflammation a symptom occurs on appears in form boils acne. Various studies are being conducted to treat these diseases. Accordingly, Lonicera japonica Citri Reticulatae Pericarpium Polyphenolic Extract (LCPE), which uses herbal preparations such as japonica, Pericarpium, Glycyrrhiza uralensis, has been used suppress...
Schwann cells (SCs), which form the peripheral myelin sheath, have unique ability to dedifferentiate and destroy sheath under various demyelination conditions. During SC dedifferentiation-associated (SAD) in Wallerian degeneration (WD) after axonal injury, SCs exhibit junctional instability, down-regulation of gene expression autophagic breakdown. However, inflammatory demyelinating neuropathy (IDN), it is still unclear how react contribute segmental before scavengers, macrophages, are...
Melatonin (N-acetyl-5-methoxytryptamine), a pineal neurohormone, is hydroxyl radical scavenger and antioxidant, plays an important role in the immune system. We studied effect of exogenous melatonin on pathogenesis experimental autoimmune encephalomyelitis (EAE). EAE was induced Lewis rats by immunization with rat spinal cord homogenates. Subsequent oral administration at 5 mg/kg significantly reduced clinical severity paralysis compared vehicle alone (p<0.01). Infiltration ED1+ macrophages...
Epidemiologic research recommends using flavonoids in the diet due to their overall health benefits. Apigetrin (Apigenin 7-O-glucoside) is a glycoside phytonutrient found fruits and vegetables known for different biological activities such as antioxidant anti-inflammatory properties. Hepatocellular cancer (HCC) major concern because of its adverse prognosis side effects chemotherapeutic agents. In present study, we determine impact apigetrin on HepG2 cells cell death mechanism. reduced...
Alpha-melanocyte stimulating hormone (α-MSH) is a that stimulates the formation of melanin, which responsible for protecting skin from UV rays. However, excessive production melanin causes pigmentation, leading to disorders, such as melasma and freckles. Using phage display technology, we screened modified hagfish VLRB (α-MSH target binding polypeptide) library polypeptides recognize α-MSH. This was expressed in E. coli produce proteins specifically bind In this study, investigated effect...