A5039479216- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience and Neuropharmacology Research
- Effects of Radiation Exposure
- Cancer-related cognitive impairment studies
- Chemotherapy-induced organ toxicity mitigation
- Nerve injury and regeneration
- Glioma Diagnosis and Treatment
- Anesthesia and Neurotoxicity Research
- Sperm and Testicular Function
- Olfactory and Sensory Function Studies
- Biochemical Analysis and Sensing Techniques
- Drug-Induced Hepatotoxicity and Protection
- Nitric Oxide and Endothelin Effects
- Neurobiology and Insect Physiology Research
- Garlic and Onion Studies
- Nanoparticles: synthesis and applications
- Bone Metabolism and Diseases
- Circadian rhythm and melatonin
- Reproductive Biology and Fertility
- Effects and risks of endocrine disrupting chemicals
- Heavy Metal Exposure and Toxicity
- Caveolin-1 and cellular processes
- Marine Biology and Environmental Chemistry
- Genomics, phytochemicals, and oxidative stress
Chonnam National University
2016-2025
Chonnam National University Hospital
2021-2023
Pusan National University
2023
Inje University Busan Paik Hospital
2021
Jeju National University
2002-2020
Kosin University
2020
RELX Group (Netherlands)
2020
Kyungpook National University
2019
Michigan State University
2005-2016
Inje University
2016
Abstract: Despite widespread use and prospective biomedical applications of copper nanoparticles (Cu NPs), their biosafety issues kinetics remain unclear. Thus, the aim this study was to compare detailed in vivo toxicity Cu NPs cupric ions (CuCl 2 ; ions) after a single oral dose. We determined physicochemical characteristics NPs, including morphology, hydrodynamic size, zeta potential, dissolution gastric (pH 1.5), vehicle 6.5), intestinal 7.8) conditions. also evaluated following...
Copper nanoparticles (Cu NPs) have great potential in electronics and biomedical fields because of their efficient thermodynamic anti-microbial properties. However, toxic effects kinetic data following repeated exposure are still unclear. We evaluated the physicochemical properties Cu NPs (25 nm) copper microparticles MPs, 14–25 μm). Comparative vivo toxicity MPs was by conducting a 28-day oral dose study at equivalent levels 0, 100, 200, 400 mg/kg/day (vehicle, 1 % hydroxypropyl...
Abstract Sterol regulatory element-binding protein (SREBP)-1c is involved in cellular lipid homeostasis and cholesterol biosynthesis highly increased nonalcoholic steatohepatitis (NASH). However, the molecular mechanism by which SREBP-1c regulates hepatic stellate cells (HSCs) activation NASH animal models patients have not been fully elucidated. In this study, we examined role of regulation LCN2 gene expression. Wild-type knockout (1cKO) mice were fed a high-fat/high-sucrose diet, treated...
Neurogenesis in the adult hippocampus, which occurs constitutively, is vulnerable to ionizing radiation. In relatively low-dose exposure of acute radiation syndrome (ARS), change hippocampal function poorly understood. This study analyzed changes apoptotic cell death and neurogenesis DGs hippocampi from ICR mice with single whole-body gamma-irradiation using TUNEL method immunohistochemical markers neurogenesis, Ki-67 doublecortin (DCX). addition, hippocampus-dependent learning memory tasks...
This study investigated the protective effects of melatonin (MLT) against doxorubicin (DXR)-induced testicular toxicity and oxidative stress in rats. DXR was given as a single intraperitoneal dose 10 mg kg−1 body weight to male rats at 1 h after MLT treatment on day 6 study. 15 administered daily by gavage for 5 days before followed an additional days. Sperm analysis, histopathological examination biochemical methods were used this investigation. caused decrease seminal vesicles, epididymal...