A5077228997- Synthesis and biological activity
- Analytical Chemistry and Chromatography
- Ion channel regulation and function
- Synthesis and Characterization of Heterocyclic Compounds
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Analytical Methods in Pharmaceuticals
- Cancer Treatment and Pharmacology
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
- Heavy Metal Exposure and Toxicity
- Metal complexes synthesis and properties
- Computational Drug Discovery Methods
- Innovative Microfluidic and Catalytic Techniques Innovation
- Cancer therapeutics and mechanisms
- Chemical Synthesis and Analysis
- Cholinesterase and Neurodegenerative Diseases
- Trace Elements in Health
- Molecular spectroscopy and chirality
- Nicotinic Acetylcholine Receptors Study
- Neuroscience and Neuropharmacology Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Click Chemistry and Applications
- Heavy metals in environment
- Synthesis and Biological Evaluation
- Phenothiazines and Benzothiazines Synthesis and Activities
University of Bari Aldo Moro
2016-2025
University of Salento
2023-2024
University of Ferrara
2021
Chromium (Cr) is a common element in the Earth’s crust. It may exist different oxidation states, Cr(0), Cr(III) and Cr(VI), with Cr(VI) being relatively stable largely predominant. Chromium’s peculiarity that its behavior relies on valence state. trace humans plays major role glucose fat metabolism. The beneficial effects of obesity types 2 diabetes are known. has been long considered an essential element, but now it reclassified as nutritional supplement. On other hand, human carcinogen...
Chirality plays an important role in the development of many pharmaceuticals, being a general property ‘handedness’; nevertheless, large number pharmaceuticals are still marketed and administered as racemates. is all around even within us; indeed, receptors enzymes chiral entities interact specific manner with drugs. Consequently, controlling enantiomeric purity isolating enantiomers from drugs remains crucial subject for analytical, clinical, regulatory purposes, thus, improving drug safety...
Curcumin, a hydrophobic polyphenol extracted from the rhizome of Curcuma longa, is now considered candidate drug for treatment neurological diseases, including Parkinson’s Disease (PD), Alzheimer’s (AD), Huntington’s (HD), Multiple Sclerosis (MS), Amyotrophic Lateral (ALS), and prion disease, due to its potent anti-inflammatory, antioxidant potential, anticancerous, immunomodulatory, neuroprotective, antiproliferative, antibacterial activities. Traditionally, curcumin has been used medicinal...
Schiff bases, named after Hugo Schiff, are highly reactive organic compounds broadly used as pigments and dyes, catalysts, intermediates in synthesis, polymer stabilizers. Lots of bases described the literature for various biological activities, including antimalarial, antibacterial, antifungal, anti-inflammatory, antiviral. also known their ability to form complexes with several metals. Very often, metals alone have demonstrated interesting antitumor activity. Given innumerable vastness...
Sweet cherry (Prunus avium L.) is one of the most popular and appreciated temperate fruit not only for its sensory nutritional properties, but also content in bioactive compounds. Consumption sweet cherries brings beneficial effects on to health, which include prevention modulatory several chronic diseases such as (diabetes mellitus, cancer, cardiovascular other inflammatory diseases). The presence natural polyphenolic compounds with high antioxidant potential might drive partly explain...
Thallium (Tl) is released into the environment, where present at very low levels, from both natural and anthropogenic sources. Tl considered as one of most toxic heavy metals; it a non-essential metal, in concentrations humans. toxicity causes dermatological gastrointestinal diseases disorders nervous system, may even result death. Many isotopes exist, with different uses. One this metal (201Tl) used cardiovascular scintigraphy for diagnosis malignant tumors such breast or lung cancer...
Heavy metals (HMs) are natural elements present in the Earth’s crust, characterised by a high atomic mass and density more than five times higher water. Despite their origin from sources, extensive usage processing of raw materials presence as silent poisons our daily products diets have drastically altered biochemical balance, making them threat to environment human health. Particularly, food chain polluted with toxic represents crucial route exposure. Therefore, impact HMs on health has...
In the developed world, pediatric obesity (PO) has been a major health concern since last century, and this condition may lead to detrimental life-long physical mental comorbidities. Currently, its prevalence increased in low- middle-income countries many high-income countries. Thus, provision of effective tailored care for children their families become vital. The social consequences COVID-19 pandemic are known everywhere, among these, it argued that had impact on PO. Overall, growth PO...