- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Mycobacterium research and diagnosis
- RNA modifications and cancer
- Pharmacological Effects of Natural Compounds
- NF-κB Signaling Pathways
- Psoriasis: Treatment and Pathogenesis
- Cytokine Signaling Pathways and Interactions
Guangxi University
2024
Guangxi University of Chinese Medicine
2024
Affiliated Hospital of North Sichuan Medical College
2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Peking Union Medical College Hospital
2020
Shanghai East Hospital
2020
Lung squamous cell carcinoma (LUSC) accounts for approximately 30% of all lung cancers that possesses the highest occurrence and mortality in cancer types. Long noncoding RNAs have been reported to modulate tumor development several decades.This research aims investigate role MAGI2-AS3 LUSC.RT-qPCR tested genes (including MAGI2-AS3, miR-374a/b-5p CADM2) expression. Cell proliferation was detected by colony formation EdU assays. migration invasion were evaluated transwell assay. Flow...
Pulsatilla saponin (Ps) was isolated from chinensis (Bunge) Regel, a traditional Chinese medicine, that has anti-proliferation, anti-inflammation, anti-tumor and immunomodulation activities. However, the anti-psoriasis activity of Ps its underlying mechanisms have not been fully elucidated. This study aims to investigate effect potential on psoriasis. underwent quality control through HPLC NMR analysis. Wound healing assay, MTT, clone EdU staining were used detect HaCaT cells proliferation....
Differentially expressed long non-coding RNAs (lncRNA) have been reported to be involved in the proliferation and migration of keratinocyte. Potassium voltage-gated channel subfamily Q member 1 overlapping transcript (KCNQ1OT1) was implicated pathogenesis various diseases, including cancer, sepsis, diabetic cardiomyopathy, atherosclerosis. In this study, influence KCNQ1OT1 on psoriatic keratinocytes explained.Cultured human keratinocyte cell line (HaCaT) incubated with tumor necrosis...