A5041919530- Healthcare Technology and Patient Monitoring
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hemodynamic Monitoring and Therapy
- Anesthesia and Sedative Agents
- Blood transfusion and management
- Intensive Care Unit Cognitive Disorders
- Patient Safety and Medication Errors
- Erythropoietin and Anemia Treatment
- Functional Brain Connectivity Studies
- Anesthesia and Pain Management
- Venous Thromboembolism Diagnosis and Management
- Blood donation and transfusion practices
- Trauma and Emergency Care Studies
- Anesthesia and Neurotoxicity Research
- Cardiac Arrest and Resuscitation
- Healthcare Operations and Scheduling Optimization
- Iron Metabolism and Disorders
- Human-Automation Interaction and Safety
- Neural dynamics and brain function
- Telemedicine and Telehealth Implementation
- Non-Invasive Vital Sign Monitoring
- Atrial Fibrillation Management and Outcomes
- Advanced Neuroimaging Techniques and Applications
- Virtual Reality Applications and Impacts
University Hospital of Zurich
2019-2025
Outcomes Research Consortium
2022-2025
University of Zurich
2017-2024
Cleveland Clinic
2022-2024
Collegium Helveticum
2017-2019
ETH Zurich
2018-2019
University of Konstanz
2016
Victoria University of Wellington
2016
Federal Foreign Office
2016
Solid State Physics Laboratory
2015
Background Patient monitoring is indispensable in any operating room to follow the patient’s current health state based on measured physiological parameters. Reducing workload helps free cognitive resources and thus influences human performance, which ultimately improves quality of care. Among many methods available assess perceived workload, National Aeronautics Space Administration Task Load Index (NASA-TLX) provides most widely accepted tool. However, only few studies have investigated...
A Patient Blood Management programme was established at the University Hospital of Zurich, along with a monitoring and feedback programme, beginning 2014 first analysis reported in 2015. Our study aimed to investigate further impact this on transfusion requirements related costs. We included adult patients discharged between 2012 2017. total 213,882 underwent analysis: 66,659 baseline period (2012-2013); 35,309 year after introduction (2014) 111,914 continued sustainability (2015-2017). The...
Nociception is the physiological response to nociceptive stimuli, normally experienced as pain. During general anesthesia, patients experience and respond stimuli by increasing blood pressure heart rate if not controlled preemptive analgesia. The PMD-200 system from Medasense (Ramat Gan, Israel) evaluates balance between analgesia during anesthesia generates nociception level (NOL) index a single finger probe. NOL unitless ranging 0 100, with values exceeding 25 indicating that exceeds We...
Abstract Background Maintaining adequate situation awareness is crucial for patient safety. Previous studies found that the use of avatar-based monitoring (Visual Patient Technology) improved perception vital signs compared to conventional showing numerical and waveform data; was further associated with a reduction perceived workload. In this study, we aimed evaluate effectiveness Visual Technology on perceptive performance workload when multiple patients at same time, such as in central...
Summary Point‐of‐care viscoelastic coagulation tests are used increasingly and enable physicians to run precise whole blood diagnostics. However, the somewhat complicated abstract presentation of results may hinder these advantages. For this reason, we developed Visual Clot as an alternative mode for thrombelastometric data. An algorithm takes existing parameters from rotational thromboelastometry creates a visual representation in form animated clot named ‘Visual Clot’. In prospective...
Extracorporeal life support (ECLS) therapy is increasingly used for cardiac and respiratory postcardiotomy, refractory cardiogenic shock cardiopulmonary resuscitation. This study aims to describe in-hospital mortality of patients requiring ECLS, identify independent predictors associated with analyze changes over time.This retrospective includes all adult ECLS cases at the University Hospital Zurich, a designated center in Switzerland, period 2007 2019.ECLS was required 679 (median age 60...
Administration of cholinesterase inhibitors in combination with anticholinergic drugs for reversal neuromuscular blocks may precipitate delirium through impairment central cholinergic transmission, which could be avoided by using sugammadex. Therefore, we tested the primary hypothesis that postoperative is less common when block reversed sugammadex than neostigmine combined glycopyrrolate or atropine.
Summary Introduction The number of tracheal intubation attempts required to reach proficiency in videolaryngoscopy with hyperangulated blades is unknown. Understanding this training requirement might guide for clinicians who perform laryngoscopy. We therefore performed a planned sub‐analysis randomised controlled trial comparing success vs. direct laryngoscopy determine the intubations videolaryngoscope blade needed provide an acceptable first‐attempt rate. Methods included from were...
Patient monitoring is central to perioperative and intensive care patient safety. Current state-of-the-art monitors display vital signs as numbers waveforms. Visual technology creates an easy-to-interpret virtual avatar model that displays sign information it would look in a real-life (eg, changes skin color from healthy cyanotic depending on oxygen saturation). In previous studies, anesthesia providers using perceived more during short glances than with conventional monitoring.We aimed...
Chronic-kidney-disease (CKD) is prevalent among adults undergoing noncardiac surgery, with surgery-related factors potentially worsening CKD or triggering acute kidney injury (AKI). We hypothesized that patients experience more function decline within one to two years post-surgery than those without CKD, particularly if they develop AKI. conducted a single-center retrospective cohort study, including surgery documented creatinine preoperative and between 1 2 after surgery. The primary...
Background: Postoperative delirium is a common and serious complication following non-cardiac surgery. A possible precipitating factor may be perioperative hemodynamic changes, with subsequent changes in brain perfusion. This study aims to investigate whether intraoperative hypotension, average blood pressure, or pressure variability are associated postoperative delirium. Methods: We conducted retrospective cohort analyzing adult surgery patients from single academic center between 2018...
Patient monitoring is critical for perioperative patient safety as anesthesiologists routinely make crucial therapeutic decisions from the information displayed on monitors. Previous research has shown that today's room improvement in areas such overload and alarm fatigue. The rationale of this study was to learn more about problems face derive suggestions next-generation We conducted a two-center qualitative/quantitative study. Initially, we interviewed 120 (physicians nurses) topic: common...
Nociception-guided intraoperative opioid administration might help reduce postoperative pain. A commonly used and validated nociception monitor system is level (NOL), which provides the index, ranging from 0 to 100, with representing no 100 extreme nociception. We tested hypothesis that NOL responses are similar in men women given remifentanil fentanyl, across various types of anesthesia, as a function American Society Anesthesiologists physical status designations, over range ages body...
BACKGROUND This study investigates the impact of preoperative calculated rivaroxaban (RXA) plasma concentration on perioperative red blood cell (RBC) loss. STUDY DESIGN AND METHODS In this retrospective single‐center study, we identified patients with RXA intake according to a determination levels within 96 hours before surgery. at beginning surgery was then from last using single‐compartment pharmacokinetic model four categories (≤20, 21‐50, 51‐100, and >100 μg/L). Patients were...
Summary In patients with pre‐operative anaemia undergoing cardiac surgery, combination treatment intravenous iron, subcutaneous erythropoietin alpha, vitamin B12 and oral folic acid reduces allogeneic blood product transfusions. It is unclear if certain types of particularly benefit from this treatment. We performed a post‐hoc analysis anaemic randomised trial on the ‘Effect ultra‐short‐term iron deficiency or surgery’. used linear regression analyses to examine efficacy compared placebo...
The cause of postoperative delirium is unknown, but it thought to result at least in part from inflammation. Metformin, besides its hypoglycemic properties, demonstrates anti-inflammatory effects systemically and the brain. We tested primary hypothesis that chronic metformin use adults with type 2 diabetes associated less during first 5 days after major noncardiac surgery. Secondary outcomes were a composite serious complications (myocardial infarction, cardiac arrest, stage 2-3 acute kidney...
Iron deficiency anemia in the perioperative setting is treated predominantly with intravenous iron formulation, of which ferric carboxymaltose may induce hypophosphatemia by modulating fibroblast growth factor 23.