Jianxu Zhang

ORCID: 0000-0002-7611-2418
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About
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Research Areas
  • Olfactory and Sensory Function Studies
  • Neurobiology and Insect Physiology Research
  • Animal Ecology and Behavior Studies
  • Animal Behavior and Reproduction
  • Neuroendocrine regulation and behavior
  • Genetic diversity and population structure
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Toxin Mechanisms and Immunotoxins
  • Genetic Mapping and Diversity in Plants and Animals
  • Wildlife Ecology and Conservation
  • Insect and Pesticide Research
  • Carbon and Quantum Dots Applications
  • Nanoparticle-Based Drug Delivery
  • Plant and animal studies
  • Circular RNAs in diseases
  • Biochemical Analysis and Sensing Techniques
  • Advanced Chemical Sensor Technologies
  • Nanoplatforms for cancer theranostics
  • Meat and Animal Product Quality
  • Genetic and phenotypic traits in livestock
  • Stress Responses and Cortisol
  • Insect and Arachnid Ecology and Behavior
  • Quantum Dots Synthesis And Properties
  • Luminescence and Fluorescent Materials

Institute of Zoology
2016-2025

University of Chinese Academy of Sciences
2016-2025

Chinese Academy of Sciences
2016-2025

Beijing Institute of Technology
2025

Chinese Academy of Agricultural Sciences
2021-2024

Jilin Academy of Agricultural Sciences
2023

Biosensores (Spain)
2022

BioMimetic Systems (United States)
2022

Changchun Institute of Applied Chemistry
2016-2019

State Key Laboratory of Polymer Physics and Chemistry
2016-2019

The possible role of uropygial gland-secreted compounds in olfactory discrimination sex or attractants the budgerigar, Melopsittacus undulatus, was investigated using behavioral 2-choice tests and gas chromatography–mass spectrometry analysis. Our data showed that female budgerigars were capable distinguishing males from females a Y maze via body odor, indicating its sexual dimorphism. When we conducted chemical assay preen gland secretions, found 4 times more volatile octadecanol,...

10.1093/chemse/bjq025 article EN Chemical Senses 2010-03-08

The cytolytic peptide melittin (MLT) is an important candidate of anticancer drug owing to its hemolytic properties. Nevertheless, clinical applications are severely restricted as a result nonspecific toxicities like hemolysis. In this work, we reported MLT-loaded zeolitic imidazolate framework-8 (MLT@ZIF-8) nanoparticles (NPs). formed MLT@ZIF-8 NPs not only possess excellent stability but also efficiently inhibit the hemolysis bioactivity MLT. Confocal scanning imaging and cytotoxicity...

10.1021/acsami.8b06125 article EN ACS Applied Materials & Interfaces 2018-06-19

This study was aimed at identifying sex pheromones of the rat (Rattus norvegicus). We characterized volatiles and semivolatiles preputial gland voided urine by using gas chromatography–mass spectrometry (GC–MS) quantified them their GC areas (abundances) percentage (relative abundances). Although all compounds other than 4-heptanone phenol detected were shared males females, quantities for some these sex-common exhibited sexual dimorphism decreased with gonadectomy. Thus, might be...

10.1093/chemse/bjn028 article EN cc-by-nc Chemical Senses 2008-05-30

Fluorescent bioprobes have been regarded as promising tools for bioimaging in recent years due to their excellent properties. However, the aggregation-caused quenching of emissions is a big limitation practice this strategy. Organic dyes with aggregation-induced emission (AIE) feature can effectively solve problem. Herein, stable fluorescent nanoparticles were prepared by supramolecular assembling carbon dots (CDs) and hydrophobic AIEgen. The formulated CDsG-AIE 1 exhibits superior physical...

10.1021/acs.chemmater.6b04894 article EN Chemistry of Materials 2016-11-18

Murine rodents are excellent models for study of adaptive radiations and speciation. Brown Norway rats (Rattus norvegicus) successful global colonizers the contributions their domesticated laboratory strains to biomedical research well established. To identify nucleotide-based speciation timing rat genomic information contributing its colonization capabilities, we analyzed 51 whole-genome sequences wild-derived sibling species, R. nitidus, identified over 20 million genetic variants in wild...

10.1093/molbev/msx157 article EN cc-by-nc Molecular Biology and Evolution 2017-05-06

We report a facile and general strategy for the preparation of aqueous colloidally stable block-copolymer grafted perovskite quantum dots with remarkable long-term thermo-, photo-, pH-stability.

10.1039/c8nr01493k article EN Nanoscale 2018-01-01

Near-infrared (NIR) imaging and photothermal therapy (PTT) based on the multifunctional cyanine dyes has shown great promise for cancer therapy. However, most of PTT agents are often limited by low drug loading, short circulation time, biocompatibility. Herein, we developed cyanine-curcumin assembling nanoparticles (CCNPs) via a single-step reprecipitation method. IR-780-C4 (Cyc4) was employed as NIR agent. Self-assembly Cyc4 curcumin in aqueous solution could be performed absence...

10.1021/acsbiomaterials.6b00315 article EN ACS Biomaterials Science & Engineering 2016-09-13

The brown rat, Rattus norvegicus, is both a notorious pest and frequently used model in biomedical research. By analyzing genome sequences of 12 wild-caught rats from their presumed ancestral range NE China, along with the sequence black rattus, we investigate selective demographic forces shaping variation genome. We estimate that recent effective population size (Ne) this species = [Formula: see text], based on silent site diversity. compare patterns diversity these genomes multiple house...

10.1093/molbev/msv126 article EN cc-by Molecular Biology and Evolution 2015-06-01

A general and simple strategy for intracellular protein delivery was developed by co-assembling carbon dots proteins. Compared to free proteins, this system can protect proteins against enzymatic hydrolysis effectively deliver EGFP into HeLa cells.

10.1039/c6tb01622g article EN Journal of Materials Chemistry B 2016-01-01

Major urinary proteins (MUPs) have been proven to be non-volatile male pheromones in mice. Here, we aimed elucidate the relationship between MUPs and dominance hierarchy, underlying molecular mechanisms. Dominance-submission was established by chronic dyadic encountering. We found that at protein level hepatic mRNA level, expression of major MUPs, including Mup20, enhanced dominant males compared with subordinate males, indicating might signal social status Meanwhile, corticotropin releasing...

10.1111/1749-4877.12165 article EN Integrative Zoology 2015-09-02

Vaccines are widely regarded as one of the most effective weapons in fight against infectious diseases. Currently, vaccines must be stored and transported at low temperatures high can lead to a loss vaccine conformation reduced therapeutic efficacy. Metal–organic frameworks (MOFs), such zeolitic imidazole framework-8 (ZIF-8), new class hybrid materials with large specific surface areas, loading rates, good biocompatibility successful systems for delivery protection. Silk fibroin (SF) has...

10.1021/acsami.3c16358 article EN ACS Applied Materials & Interfaces 2024-02-07

Transcranial electrical stimulation, as a means of neural modulation, is increasingly favored by researchers. The distribution and magnitude the electric field generated within brain may directly affect results modulation. Therefore, it important to clarify change trend cortical determinants induced in endodermis at different ages during adult life cycle. In this study, we used SimNIBS software perform MR image segmentation realistic head model reconstruction on 476 individuals (aged 18 88...

10.3390/bios15030185 article EN cc-by Biosensors 2025-03-13

Abstract: Herein, DNA duplex was constructed through the hybridization of adenosine triphosphate (ATP)-responsive aptamer and its cDNA in which GC-rich motif could be used to load doxorubicin (DOX), then, cationic polymer PEI25K as a carrier simultaneously condense DOX-Duplex Bcl-2 siRNA prepare ternary nanocomplex polyethylenimine (PEI)/DOX-Duplex/siRNA. The ATP concentration gradient between cytosol extracellular environment achieve stable loading DOX rapid drug release an ATP-responsive...

10.2147/ijn.s135086 article EN cc-by-nc International Journal of Nanomedicine 2017-07-01

<title>Abstract</title> Interspecific interactions are crucial for maintaining ecological balance. Foraging and food consumption fundamental the survival of animals. In natural environments, wild rodents feed on various insect species, including moth larvae, odor-guided evaluation potential resources is a critical step in initiating feeding behavior. However, mechanisms by which seek prey remain poorly understood. Herein, we employed laboratory-based predator-prey interaction system using...

10.21203/rs.3.rs-6348387/v1 preprint EN Research Square (Research Square) 2025-04-02

The Asian house rat (Rattus tanezumi) and the brown norvegicus) are closely related species partially sympatric in southern China. Over past 20 years, R. tanezumi has significantly expanded northward China replaced native subspecies, n. humiliatus. Although invasive often more aggressive than species, we did not observe interspecific physical aggression between Here, focused on whether or was superior to humiliatus terms of nonphysical competition, which is primarily mediated by chemical...

10.1186/s12983-017-0202-4 article EN cc-by Frontiers in Zoology 2017-04-12
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