A5085588529- Immune Response and Inflammation
- Viral gastroenteritis research and epidemiology
- Salmonella and Campylobacter epidemiology
- Phagocytosis and Immune Regulation
- Inhalation and Respiratory Drug Delivery
- Immunotherapy and Immune Responses
- Escherichia coli research studies
- Bacteriophages and microbial interactions
- T-cell and B-cell Immunology
- Clostridium difficile and Clostridium perfringens research
- Hepatitis B Virus Studies
- Animal Virus Infections Studies
- Immune cells in cancer
- Single-cell and spatial transcriptomics
Indian Institute of Science Bangalore
2017-2023
Abstract The thymus is known to atrophy during infections; however, a systematic study of changes in thymocyte subpopulations has not been performed. This aspect was investigated, using multi-color flow cytometry, oral infection mice with Salmonella Typhimurium ( S . Typhimurium). major highlights are: First, block the developmental pathway CD4 − CD8 double negative (DN) thymocytes observed. Second, + positive (DP) thymocytes, mainly DP1 (CD5 lo CD3 ) and DP2 hi int ), but DP3 subsets are...
Summary The development of immunocompetent T cells entails a complex pathway differentiation in the thymus. Thymic atrophy occurs with ageing and during conditions such as malnutrition, infections cancer chemotherapy. comparative changes thymic subsets under different modes mechanisms involved are not well characterized. These aspects were investigated, using mice infected Salmonella Typhimurium, injection lipopolysaccharide ( LPS ), an inflammatory but non‐infectious stimulus, etoposide...
Abstract Humans are exposed to numerous synthetic foreign particulates in the form of environmental pollutants and diagnostic or therapeutic agents. Specialized immune cells (phagocytes) clear these by phagocytosing attempting degrade them. The process recognition internalization may trigger changes function phagocytes. Some changes, especially ability a particle-loaded phagocyte take up neutralize pathogens, remains poorly studied. Herein, we demonstrate that uptake non-stimulatory...