A5057606094- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- Antibiotic Use and Resistance
- COVID-19 impact on air quality
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Bartonella species infections research
- Climate Change and Health Impacts
- Antibiotic Resistance in Bacteria
- Peripheral Neuropathies and Disorders
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Escherichia coli research studies
- Vector-borne infectious diseases
- Vibrio bacteria research studies
- Health and Medical Education
- Genital Health and Disease
- Listeria monocytogenes in Food Safety
- Respiratory viral infections research
- Rabies epidemiology and control
- Microbial infections and disease research
- Antifungal resistance and susceptibility
- SARS-CoV-2 and COVID-19 Research
Instituto Nacional de Salud
2015-2024
Universidad Privada San Juan Bautista
2022-2023
Universidad Alas Peruanas
2019
Campylobacter is the leading cause of human bacterial gastroenteritis worldwide and has a major impact on global public health. Whole Genome Sequencing (WGS) powerful tool applied in study foodborne pathogens. The objective present was to apply WGS determine genetic diversity, virulence factors determinants antimicrobial resistance populations C. jejuni coli Peru. A total 129 strains (108 21 coli) were sequenced using Illumina Miseq platform. In silico MLST analysis identified high diversity...
Objectives. To describe the phenotypic and genotypic patterns of antimicrobial resistance Salmonella Infantis in Peru. Materials Methods. Two hundred ninety-seven strains sp. submitted to National Institute Health (INS, Spanish) during 2014-2016 were analyzed. The phenotypically characterized by microbiological, serological, susceptibility tests. Based on patterns, 46 selected genetically next generation sequencing. Results. 193/297 (65%) identified, which 143 (74.1%) multidrug-resistant...
To describe the frequency of antimicrobial resistance rates and spatial-temporal distribution Shigella species from last 10 years in Peru.A cross-sectional descriptive study was carried out. A total 1668 strains, remitted as part national enteric pathogen surveillance 2011 to 2020, were analysed. The strains confirmed by conventional tests serotyped with polyvalent monovalent antibodies. Also, susceptibility performed according Kirby-Bauer method.The most frequent S. sonnei (49.2%), followed...
To evaluate in vitro antimicrobial susceptibility to chloramphenicol (CHL) and ciprofloxacin (CIP) strains of Bartonella bacilliformis from areas that are endemic Bartonellosis Peru, through three laboratory methods.Antimicrobial CHL CIP 100 isolated patients the regions Ancash, Cusco, Cajamarca, Lima La Libertad were evaluated. Strains evaluated by: disk diffusion, E-test agar dilution.26% resistant 1% CHL. Similar patterns sensitivity / resistance obtained all methods.Bartonella...
Abstract The main strategy for response and control of COVID-19 demands the use rapid, accurate diagnostic tests aimed at first point health care. During emergency, an increase in asymptomatic symptomatic cases results a great demand molecular tests, which is promoting development application rapid technologies. In this study, we describe evaluation RT-LAMP to detect SARS-CoV-2 based on three genes ( ORF1ab , M N genes) monoplex triplex format. assays were compared with gold standard method...
Non-typhoidal Salmonella (NTS) is one of the leading causes foodborne outbreaks worldwide, especially in low- and middle-income countries such as Peru. To understand dynamics NTS serotypes circulating country, whole genomes 1122 strains from 1998 to 2018 were analyzed using phylogenomic comparative genomics tools. A total 40 different Sequences Type (STs) identified, five most frequent being ST-32 (S. Infantis, 37.25%), ST-11 Enteritidis, 23.8%), ST-19 Typhimurium, 14.17%), ST-31 Newport,...
Abstract Objectives The role of the environment and climate in transmission case fatality rates SARS-CoV-2 is still being investigated a year into pandemic. Elevation air quality are believed to be significant factors development pandemic, but influence additional environmental remains unclear. Methods We explored relationship between cumulative number infections mortality cases with (temperature, precipitation, solar radiation, water vapor pressure, wind), data (elevation, normalized...
The presence of amino acid changes in GyrA, GyrB, ParC, ParE, and a proposed chromosomal chloramphenicol acetyl transferase (CAT), as well mutations at 23S rRNA, were established by PCR sequencing 38 B. bacilliformis clinical isolates from four different areas Peru. Eighteen out 24 (75%) showing ciprofloxacin resistance for both disk-diffusion e-test presented substitutions GyrA (G89C, six isolates, A91V, 1 isolate) GyrB (S474F, 10 isolates) or (GyrA D95N S474F, one isolate). Two 14...
Candida auris es un hongo emergente que ha cobrado en corto tiempo gran relevancia como problema de salud pública mundial. Se reporta por primera vez el Perú la presencia 3 pacientes adultos internados hospital nacional alta complejidad último trimestre del año 2020 plena pandemia COVID-19. Los fueron hospitalizados UCI, sin embargo, solo 2 se aisló dicho germen mientras estaban UCI. tenían varias comorbilidades y tiempos prolongados hospitalización desde su admisión hasta tener primer...
The COVID-19 pandemic remains the main public health problem, due to quick and easy dissemination of causal agent, SARS-CoV-2 virus, around world. Since beginning pandemic, an opportune laboratory diagnosis has been critical respond this emergency, RT-qPCR used as reference molecular tests for detection SARS-CoV-2.In study, we performed evaluation a SMARTCHEK platform (SMARTCHEK, Genesystem) based on amplification RdRp N gene markers. was evaluated with nasopharyngeal swab samples...
Abstract In recent years, the worldwide incidence of diarrheal diseases caused by Campylobacter jejuni has been increasing, causing large-scale outbreaks in developing countries, which added to capacity microorganism cause Guillain-Barré syndrome (GBS), increasing need for rapid and timely diagnosis stop prevent outbreaks. this study, a loop-mediated isothermal amplification (LAMP) assay based on cdtC gene was developed evaluated detection C. , using 91 strains standardization validation....
El síndrome de Guillain Barré es una enfermedad derivada del compromiso en las neuronas sistema nervioso periférico por respuesta descontrolada inmune que conduce daño axonal y/o desmielinización. objetivo este reporte fue describir los 10 primeros casos sospechosos Síndrome Piura. Se logró identificar la presencia Campylobacter jejuni muestras heces 80% pacientes reportados. Es muy importante reconocer rápida y oportunamente al paciente con diagnóstico sospechoso Barré, realizar estudios...
ABSTRACT The role of the environment and climate in transmission case-fatality rates SARS-CoV-2 is still being investigated. Elevation air quality are believed to be significant factors current development pandemic, but influence additional environmental remain unclear. In this study, we explored relationship between cumulative number infections mortality cases with (temperature, precipitation, solar radiation, water vapor pressure, wind), data (elevation, NDVI, PM 2.5 NO 2 concentration),...