A5077068545- Pancreatic and Hepatic Oncology Research
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- Neuroendocrine Tumor Research Advances
- AI in cancer detection
- Advanced X-ray and CT Imaging
- Parasitic infections in humans and animals
- Radiation Dose and Imaging
- Peptidase Inhibition and Analysis
- Cardiac Imaging and Diagnostics
- Liver Disease Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Neuroblastoma Research and Treatments
- Glioma Diagnosis and Treatment
- Inflammatory Bowel Disease
- Fetal and Pediatric Neurological Disorders
- Radiopharmaceutical Chemistry and Applications
- Gastrointestinal Tumor Research and Treatment
- Prostate Cancer Diagnosis and Treatment
- COVID-19 diagnosis using AI
- Advanced MRI Techniques and Applications
- Urologic and reproductive health conditions
- Pancreatitis Pathology and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
Mayo Clinic
2016-2025
Mayo Clinic in Arizona
2016-2024
WinnMed
2016-2024
Mayo Clinic in Florida
2024
University of Minnesota Rochester
2018
University Medical Center
2017
University of Mississippi Medical Center
2012-2017
University of Toledo Medical Center
2017
Cleveland Clinic
2012-2016
Harvard University
2014
To identify predictive factors associated with operative morbidity, mortality, and survival outcomes in patients borderline resectable (BR) or locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC) undergoing total neoadjuvant therapy (TNT).The optimal preoperative treatment sequencing for BR/LA PDA is unknown. TNT, systemic chemotherapy followed by chemoradiation (CRT), addresses both occult metastases positive margin risks thus a potentially strategy; however, of perioperative are...
Background: Neoadjuvant therapy (NAT) is used in borderline resectable/locally advanced (BR/LA) pancreatic ductal adenocarcinoma (PDAC). Anatomic imaging (CT/MRI) poorly predicts response, and biochemical (CA 19-9) markers are not useful (nonsecretors/nonelevated) many patients. Pathologic response highly survival post-NAT, but only known postoperatively. Because metabolic (FDG-PET) reveals primary tumor viability, this study aimed to evaluate our experience with preoperative FDG-PET...
To measure the effect of reduced radiation exposure on low-contrast low-attenuation liver lesion detection in an anthropomorphic abdominal phantom by using filtered back projection (FBP) and sinogram-affirmed iterative reconstruction.Eighteen radiologists blinded to study design interpreted randomized image data sets that contained 36 spherical simulated lesions three sizes attenuation differences (5-mm diameter: 12, 18, 24 HU less than 90-HU background insert; 10- 15-mm 6, 18 attenuation)...
Borderline Resectable and Locally Advanced Pancreatic Cancer: FDG PET/MRI CT Tumor Metrics for Assessment of Pathologic Response to Neoadjuvant Therapy Prediction SurvivalAnanya Panda, MD1, Ishan Garg, MBBS1, Mark J. Truty, MD2, Timothy L. Kline, PhD1, Matthew P. Johnson, MS3, Eric C. Ehman, Garima Suman, Deema A. Anaam, Bradley Kemp, Geoffrey B. MD, Thorvardur R. Halfdanarson, MD4, Sudhakar K. Venkatesh, Jeff Fidler, MD1 Ajit H. Goenka, MD1Audio Available | Share
Purpose To assess image noise, contrast-to-noise ratio (CNR) and detectability of low-contrast, low-attenuation liver lesions in a semianthropomorphic phantom by using either discrete circuit (DC) detector filtered back projection (FBP) or an integrated (IC) iterative reconstruction (IR) with changes radiation exposure size. Materials Methods An anthropomorphic without 5-cm-thick fat-mimicking ring (widths, 30 40 cm) containing inserts four spherical was scanned five settings on each two...
Purpose To compare the diagnostic accuracy and image quality of computed tomographic (CT) enterographic images obtained at half dose reconstructed with filtered back projection (FBP) sinogram-affirmed iterative reconstruction (SAFIRE) those full-dose CT FBP for active inflammatory terminal or neoterminal ileal Crohn disease. Materials Methods This retrospective study was compliant HIPAA approved by institutional review board. The requirement to obtain informed consent waived. Ninety subjects...
Purpose To develop a two‐stage three‐dimensional (3D) convolutional neural networks (CNNs) for fully automated volumetric segmentation of pancreas on computed tomography (CT) and to further evaluate its performance in the context intra‐reader inter‐reader reliability at full dose reduced radiation CTs public dataset. Methods A dataset 1994 abdomen CT scans (portal venous phase, slice thickness ≤ 3.75‐mm, multiple vendors) was curated by two radiologists (R1 R2) exclude cases with pancreatic...
Prostate-specific membrane antigen (PSMA) is a validated target for molecular diagnostics and targeted radionuclide therapy. Our purpose was to evaluate PSMA expression in hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), hepatic adenoma (HCA); investigate the genetic pathways HCC associated with expression; detection rate
The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific professional organization founded in 1954 to promote the science, technology, practical application nuclear medicine. European Association (EANM) a non-
11C-Choline PET/CT for Detection and Localization of Parathyroid AdenomasAhmad Parvinian1, Erica L. Martin-Macintosh1, Ajit H. Goenka1, Jolanta M. Durski1, Brian P. Mullan1, Brad J. Kemp1 Geoffrey B. Johnson1Audio Available | Share
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal malignancy. Surgical resection the only curative modality combined with neoadjuvant chemotherapy to improve survival. Given limitations of traditional responses such as cross-sectional imaging (CT/MRI) or tumor markers, carbohydrate antigen 19-9 (CA19-9), 2023 National Comprehensive Cancer Network guidelines included 18 F-fluorodeoxyglucose (FDG)-PET adjunct assess response chemotherapy. There are common...