A5024443422- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Healthcare Decision-Making and Restraints
- Nosocomial Infections in ICU
- Cardiac Arrest and Resuscitation
- Pharmaceutical Practices and Patient Outcomes
- Family and Patient Care in Intensive Care Units
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Health, Medicine and Society
- Anesthesia and Neurotoxicity Research
- Poisoning and overdose treatments
- Linguistics and Discourse Analysis
- Healthcare Systems and Practices
- Antifungal resistance and susceptibility
- Health Sciences Research and Education
- Traumatic Brain Injury Research
- Pediatric Pain Management Techniques
- Antibiotics Pharmacokinetics and Efficacy
- Cardiac, Anesthesia and Surgical Outcomes
- Epilepsy research and treatment
- Innovations in Medical Education
- Patient Safety and Medication Errors
- Alcoholism and Thiamine Deficiency
Université de Montréal
2015-2025
Montreal General Hospital
2011-2025
McGill University
2012-2025
McGill University Health Centre
2007-2023
Hôpital du Sacré-Cœur de Montréal
2004-2019
Lakeshore General Hospital
2019
Jewish General Hospital
2019
Deleted Institution
2016
Pharmac
2015
Centre Hospitalier de l’Université de Montréal
2012
Physical restraint (PR) use in the intensive care unit (ICU) has been associated with higher rates of self-extubation and prolonged ICU length stay. Our objectives were to describe patterns predictors PR use. We conducted a secondary analysis prospective observational study analgosedation, antipsychotic, neuromuscular blocker, practices 51 Canadian ICUs. Data collected prospectively for all mechanically ventilated adults admitted during two-week period. tested patient, treatment, hospital...
Appropriate management of analgo-sedation in the intensive care unit (ICU) is associated with improved patient outcomes. Our objectives were: a) to describe utilization regimens and strategies (assessment using scales, protocolized daily sedation interruption (DSI)) b) compare perceptions challenging these strategies, amongst physicians nurses.In 101 adult ICUs Belgium, we surveyed all a sample seven nurses per ICU. A multidisciplinary team designed survey tool based on previous qualitative...
Opioids and benzodiazepines are frequently used in the intensive care unit (ICU). Regular use prolonged exposure to opioids ICU patients followed by abrupt tapering or cessation may lead iatrogenic withdrawal syndrome (IWS). IWS is well described pediatrics, but no prospective study has evaluated this adult patients. The objective of was determine incidence caused a critically ill population. This multicenter cohort conducted at two level-1 trauma ICUs between February 2015 September...
OBJECTIVES: Iatrogenic withdrawal syndrome (IWS) associated with opioid and sedative use for medical purposes has a reported high prevalence morbidity. This study aimed to determine the prevalence, utilization, characteristics of weaning IWS policies/protocols in adult ICU population. DESIGN: International, multicenter, observational, point study. SETTING: Adult ICUs. PATIENTS: All patients aged 18 years older on date data collection who received parenteral opioids or sedatives previous 24...
BACKGROUND: The significance of Candida species in respiratory tract (RT) secretions critically ill patients is unclear. METHODS: A retrospective analysis the Canadian ventilator‐associated pneumonia (VAP) trial was conducted. Only with suspected VAP whose initial cultures failed to grow any known pathogens were included. Using two fundamentally different statistical techniques that adjusted for important confounding variables, clinical outcomes recovered from RT compared not positive...
The pharmacokinetics of baclofen is well delineated in subjects with normal kidney function (KF); however, data patients chronic disease (CKD) are not and dosage recommendations remain empirical. effects CKD on were assessed through a multi-center, open-label, single 5-mg dose, study. KF was measured as the creatinine clearance (CrCL) calculated Cockroft–Gault (C–G) equation or estimated glomerular filtration rate (eGFR) using subjects' CKD-EPI equation. Subjects assigned to 1 4 groups based...
To evaluate the efficacy and safety of intravenous potassium phosphate administered in a fixed-dose regimen critically ill patients.Prospective, unblind study.Surgical-medical intensive care unit (ICU).Patients who developed hypophosphatemia during their ICU admission.Patients with serum concentration between 1.27 2.48 mg/dL (group 1) those 1.24 or less 2) received 15 30 mmol, respectively, as salt via central line over 3 hours.Normalization within 6 hours infusion, development arrhythmias...
Lithium (Li) is a first-line treatment for bipolar disorder but has narrow therapeutic index. Treatment of Li toxicity includes supportive measures and hemodialysis in severe cases, this modality not always immediately available. Sodium polystyrene sulfonate (SPS, Kayexalate), cation exchanger, been promising animal models human reports to reduce absorption enhance elimination Li.A retrospective cohort study was conducted. All cases chronic intoxication were reviewed two adult-care hospitals...
Intensive care unit (ICU)-acquired delirium has been associated with increased morbidity and mortality. Prevention strategies including modification of risk factors are emphasized by practice guidelines. No study specifically evaluated modifiable in trauma ICU patients. Our goal was to evaluate for among patients admitted the ICU.Prospective observational study.Two level 1 centers.Patients 18 years age or older mild moderate traumatic brain injury were eligible study.Delirium assessed daily...
Agitation is a common complication after an acute TBI in ICU patients. Professionals have range of strategies to address agitation. Yet the absence evidence-based guidelines and how these are implemented complicates management safety may often be compromised for both professionals This project explores experiences attitudes ICU-nurses better understand agitated behaviors TBI-patients. Semi-structured interviews were conducted with 12 from two Level-1 trauma centers Canada. The explored...