- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Antifungal resistance and susceptibility
- Antibiotics Pharmacokinetics and Efficacy
- Traumatic Brain Injury and Neurovascular Disturbances
- Organ Transplantation Techniques and Outcomes
- Trauma and Emergency Care Studies
- Acute Kidney Injury Research
- Mechanical Circulatory Support Devices
- Frailty in Older Adults
- Electrolyte and hormonal disorders
- Renal Transplantation Outcomes and Treatments
- Ultrasound in Clinical Applications
- Family and Patient Care in Intensive Care Units
- Spinal Cord Injury Research
- Anesthesia and Sedative Agents
- Organ Donation and Transplantation
Hôpital du Sacré-Cœur de Montréal
2016-2025
Université de Montréal
2015-2024
Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal
2018-2024
Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean
2018-2024
Montreal Heart Institute
2018-2024
Centre intégré universitaire de santé et de services sociaux du Nord-de-l’Île-de-Montréal
2023
Western University
2023
Creative Research Enterprises (United States)
2017
Centre Hospitalier de l’Université de Montréal
2017
Kingston General Hospital
2014
Seriously ill hospitalized patients have identified communication and decision making about goals of care as high priorities for quality improvement in end-of-life care. Interventions to improve are more likely succeed if tailored existing barriers.To determine, from the perspective hospital-based clinicians, (1) barriers impeding with seriously their families (2) own willingness acceptability other clinicians engage this process.Multicenter survey medical teaching units nurses, internal...
<h3>Importance</h3> The evidence for benefit of convalescent plasma critically ill patients with COVID-19 is inconclusive. <h3>Objective</h3> To determine whether would improve outcomes adults COVID-19. <h3>Design, Setting, and Participants</h3> ongoing Randomized, Embedded, Multifactorial, Adaptive Platform Trial Community-Acquired Pneumonia (REMAP-CAP) enrolled randomized 4763 suspected or confirmed between March 9, 2020, January 18, 2021, within at least 1 domain; 2011 were to open-label...
To compare the effect of pressure support ventilation and neurally adjusted ventilatory assist on breathing pattern, patient-ventilator synchrony, diaphragm unloading, gas exchange. Increasing level can increase tidal volume, reduce respiratory rate, lead to delayed ventilator triggering cycling. Neurally uses electrical activity control timing delivery is expected enhance synchrony.Prospective, comparative, crossover study.Adult critical care unit in a tertiary university hospital.Fourteen...
Background: The recent large randomized controlled trial of glutamine and antioxidant supplementation suggested that high‐dose is associated with increased mortality in critically ill patients multiorgan failure. objectives the present analyses were to reevaluate effect after controlling for baseline covariates identify potentially important subgroup effects. Materials Methods : This study was a post hoc analysis prospective factorial 2 × conducted 40 intensive care units North America...
Frailty is common in critically ill patients but the timing and optimal method of frailty ascertainment, trajectory relationship with care processes remain uncertain. We sought to elucidate as measured by Clinical Scale (CFS) Index (FI).
Objective, Design and Patients: The risk of acute kidney injury (AKI) associated with hydroxyethyl starch may be limited to higher molecular weight agents. We retrospectively evaluated the AKI using pentastarch 10% (250 kDa, 0.45) in a random cohort 563 patients operated for cardiac surgery at university hospital. Measures: assessed previously identified preoperative, perioperative, postoperative factors, volume given until end first day. defined by 50% rise serum creatinine within 4 days...
Heyland, Daren; Muscedere, John; Wischmeyer, Paul E.; Cook, Deborah; Jones, Gwynne; Albert, Martin; Elke, Gunnar; Berger, Mette M.; Day, Andrew G. for the Canadian Critical Care Trials Group Author Information
Focused bedside ultrasound is rapidly becoming a standard of care to decrease the risks complications related invasive procedures. The purpose this study was assess whether adding curriculum junior residents an educational intervention combining web-based e-learning and hands-on training would improve residents' proficiency in different clinical applications as compared using traditional apprenticeship teaching method alone.Junior (n = 39) were provided with two interventions (vascular...
Study Objective. To demonstrate dosing adjustment difficulties of argatroban encountered in critically ill patients with acute liver dysfunction who are receiving continuous renal replacement therapy. Design. Case description. Setting. Medical and surgical intensive care unit a tertiary care, university‐affiliated hospital. Patients. Four consecutive proven heparin‐induced thrombocytopenia (HIT), failure requiring therapy, various levels transient hepatic impairment. Intervention....
BACKGROUND: The significance of Candida species in respiratory tract (RT) secretions critically ill patients is unclear. METHODS: A retrospective analysis the Canadian ventilator‐associated pneumonia (VAP) trial was conducted. Only with suspected VAP whose initial cultures failed to grow any known pathogens were included. Using two fundamentally different statistical techniques that adjusted for important confounding variables, clinical outcomes recovered from RT compared not positive...
Purpose: In light of point-of-care ultrasonography’s (POCUS) recent rise in popularity, assessment its impact on diagnosis and treatment the intensive care unit (ICU) is key importance. Methods: Ultrasound examinations were collected through an ultrasound reporting software 6 multidisciplinary ICU units from 3 university hospitals Canada United States. This database included a self-reporting questionnaire to assess findings treatment. We retrieved results these questionnaires analyzed them...
OBJECTIVES: Respiratory failure secondary to COVID-19 is associated with morbidity and mortality. Current anti-inflammatory therapies are effective but given systemically have significant side effects. Furosemide has properties, can be administered by inhalation, inexpensive. We investigated the efficacy of nebulized furosemide as an adjunctive therapy for respiratory failure. DESIGN: A double-blind, randomized, placebo-controlled trial. SETTING: Multicenter ICU study. PATIENTS: Adults...
Arginine vasopressin is being used increasingly to treat vasodilatory hypotension, although little known of its effects on regional perfusion. hemodynamic in physiology are mainly mediated through the V1a receptor blood vessels. To investigate this further, we studied effect arginine systemic and renal flow anesthetized, ventilated rabbits given either intravenous saline or endotoxin, impact blocking receptors.Prospective, randomized, controlled study.Animal research laboratory.Male White...