A5102992749- Palliative Care and End-of-Life Issues
- Family and Patient Care in Intensive Care Units
- Patient Dignity and Privacy
- Health Systems, Economic Evaluations, Quality of Life
- Meta-analysis and systematic reviews
- Geriatric Care and Nursing Homes
- Childhood Cancer Survivors' Quality of Life
- Patient-Provider Communication in Healthcare
- Grief, Bereavement, and Mental Health
- Heart Failure Treatment and Management
- Interprofessional Education and Collaboration
- Ethics in medical practice
- Radiation Dose and Imaging
- Healthcare Policy and Management
- Statistical Methods in Clinical Trials
- Radiology practices and education
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Innovations in Medical Education
- Ethics in Clinical Research
- Primary Care and Health Outcomes
- Spine and Intervertebral Disc Pathology
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Healthcare cost, quality, practices
Wuhan University of Technology
2025
Trillium Health Centre
2019-2024
Third People's Hospital of Huzhou
2024
Credit Valley Hospital
2020-2023
McMaster University
2012-2021
Impact
2017-2020
Harvard University
2004-2020
Dana-Farber Cancer Institute
2020
Brigham and Women's Hospital
2020
Queens University
2017-2019
Seriously ill hospitalized patients have identified communication and decision making about goals of care as high priorities for quality improvement in end-of-life care. Interventions to improve are more likely succeed if tailored existing barriers.To determine, from the perspective hospital-based clinicians, (1) barriers impeding with seriously their families (2) own willingness acceptability other clinicians engage this process.Multicenter survey medical teaching units nurses, internal...
<h3>Importance</h3> The discontinuation of randomized clinical trials (RCTs) raises ethical concerns and often wastes scarce research resources. epidemiology discontinued RCTs, however, remains unclear. <h3>Objectives</h3> To determine the prevalence, characteristics, publication history RCTs to investigate factors associated with RCT due poor recruitment nonpublication. <h3>Design Setting</h3> Retrospective cohort based on archived protocols approved by 6 ethics committees in Switzerland,...
The goal of end-of-life (EOL) communication and decision making is to create a shared understanding about person's values treatment preferences that will lead plan care consistent with these preferences. Improvements in at the EOL have been identified as high priority from patient family point view.The purpose this study was develop quality indicators related making.We convened multidisciplinary panel experts definitions, conceptual framework making, using modified Delphi method. We...
The type of outpatient physician care after an emergency department visit for heart failure may affect patients' outcomes.Using the National Ambulatory Care Reporting System, we examined and outcomes patients who visited were discharged from in Ontario, Canada (April 2004 to March 2007). Early collaborative by a cardiologist primary (PC) within 30 days discharge was compared with PC alone. 10 599 (age, 74.9±11.9 years; 50.2% male) provided alone (n=6596), (n=535), or concurrently both...
Studies of a TAZ knockout mouse reveal novel function the transcriptional regulator TAZ, that is, as binding partner F-box protein β-Trcp. TAZ−/− mice develop polycystic kidney disease (PKD) and emphysema. The calcium-permeable cation channel polycystin 2 (PC2) is overexpressed in kidneys result decreased degradation via an SCFβ-Trcp E3 ubiquitin ligase pathway. Replacements serines phosphodegron motif prevent β-Trcp PC2 degradation. Coexpression cytoplasmic fragment 1 blocks PC2-TAZ...
<h3>Background:</h3> The guideline-recommended elements to include in discussions about goals of care with patients serious illness are mostly based on expert opinion. We sought identify which most important and their families. <h3>Methods:</h3> used a cross-sectional study design involving from 9 Canadian hospitals. asked older adult family members the occurrence importance 11 goals-of-care discussions. In addition, we assessed concordance between prescribed patient preferences, measured...