A5018713807- Neurobiology of Language and Bilingualism
- Infant Nutrition and Health
- Biomedical and Chemical Research
- Linguistic research and analysis
- Neonatal Respiratory Health Research
- Escherichia coli research studies
- Language Development and Disorders
- Interpreting and Communication in Healthcare
- Enterobacteriaceae and Cronobacter Research
- Breastfeeding Practices and Influences
- Cytomegalovirus and herpesvirus research
- Linguistic Education and Pedagogy
- Probiotics and Fermented Foods
- Diabetes and associated disorders
- Spatial Neglect and Hemispheric Dysfunction
- Dementia and Cognitive Impairment Research
- Medical Practices and Rehabilitation
- Infant Health and Development
- Glycosylation and Glycoproteins Research
- Stroke Rehabilitation and Recovery
Bundesverband Glaukom-Selbsthilfe
2013-2015
Universitätsklinikum Aachen
2010-2011
RWTH Aachen University
2010
Google (United States)
2010
Boston Children's Hospital
2001
Heinrich Heine University Düsseldorf
1992-1999
Düsseldorf University Hospital
1992-1999
University of Cologne
1992
Universitätskinderklinik
1992
We investigated the presence of factors in human milk that inhibit invasion pathogenic bacteria. The effect fat globule membrane (HMFGM) components on adhesion cloned S-fimbriated Escherichia coli to buccal epithelial cells was analyzed. S fimbriae are a common feature E. strains causing sepsis and meningitis newborns bound epithelia via sialyl-(alpha-2-3)galactoside structures. Human globules (HMFG) could be agglutinated by above-mentioned Agglutination inhibited fetuin, glycophorin, alpha...
Expression of S‐fimbriae is frequent in Escherichia coli strains causing sepsis and meningitis the newborn period. We analysed ability human skim milk to inhibit adhesion S‐fimbriated E. buccal epithelia. Adhesion was inhibited by up 90% using colostrum (5%) 50% with mature (5%), indicating that this anti‐infective mechanism depends on period lactation. Elimination 99% immunoglobulins 91% lactoferrin affinity chromatography had no effect inhibition adhesion. After separation high‐ (> 10...
Summary We investigated the ability of meconium, feces from human milk-fed (HMF) newborns, and formula-fed (FF) newborns to inhibit adhesion S-fimbriated E. coli buccal epithelial cells. S-fimbriae are a common property strains causing sepsis meningitis in neonates. Meconium had highest content neuraminic acid strongest inhibitory effect on bacterial adhesion. HMF also exerted high activity while FF was markedly less active: To achieve effects comparable sixfold amount required....
The aim of this study was to prove the efficacy supervised self-training for individuals with aphasia. Linguistic and communicative performance in structured dialogues represented main parameters.In a cross-over design randomized matched pairs, 18 chronic aphasia were examined during 12 weeks home training. Intensive language training, assisted by an electronic learning device (B.A.Bar), compared nonlinguistic Language performance, abilities, cognitive abilities controlled before after each...
Derzeit stehen für die Diagnostik kindlicher Aphasien kaum Testinstrumente zur Verfügung. Insbesondere fehlt ein Test Erfassung kommunikativ-pragmatischer Leistungen. Der Szenario-Kids ist in der Entwicklung befindliches Diagnostikinstrument multimodaler Kommunikationsfähigkeiten bei 8- bis 15- jährigen Kindern mit Aphasie. Zunächst wurden 2 inhaltlich parallele Testversionen A und B konstruiert 22 sprachgesunden erprobt. Anhand dieser Ergebnisse wurde endgültige Version des erstellt. Dieser...
In der vorliegenden Studie wurde das Sprachsystematische Aphasiescreening (SAPS) in seiner modifizierten Version revalidiert. Das SAPS ermöglicht die Abbildung individueller Leistungsprofile, von denen Therapieschwerpunkte abgeleitet werden können. Es außerdem ein PC-gestütztes, supervidiertes Eigentraining entwickelt und validiert, auf den Anforderungen des aufbaut kombiniert mit einer SAPS-basierten Therapie durchgeführt kann.
SAPS-'Sprachsystematisches Aphasiescreening'-is a novel language-systematic aphasia screening developed for the German language, which already had been positively evaluated. It offers fast assessment of modality-specific psycholinguistic components at different levels complexity and derivation impairment-based treatment foci from individual performance profile. However, SAPS has not yet evaluated in combination with new SAPS-based treatment.To replicate practicality to investigate...
Mit der Einführung ICF (International Classification of Functioning, Disability and Health) gewinnen kommunikativ-pragmatische Ansätze und Methoden Unterstützten Kommunikation (UK) in Aphasierehabilitation an Bedeutung. In vorliegenden Untersuchung wird B.A.Bar, ein elektronisches Hilfsmittel mit Sprachausgabe, eingesetzt, welches sowohl als Kommunikationshilfe auch Sprachtrainingshilfe verwendet werden kann. Bei einem Patienten chronischem Agrammatismus wurde die spontane selbstinstruierte...
Summary We investigated the ability of meconium, feces from human milk‐fed (HMF) newborns, and formula‐fed (FF) newborns to inhibit adhesion S‐fimbriated E. coli buccal epithelial cells. S‐fimbriae are a common property strains causing sepsis meningitis in neonates. Meconium had highest content neuraminic acid strongest inhibitory effect on bacterial adhesion. HMF also exerted high activity while FF was markedly less active: To achieve effects comparable sixfold amount required....