A5042107624- 3D Printing in Biomedical Research
- Genomics and Rare Diseases
- Pain Mechanisms and Treatments
- Genetics and Neurodevelopmental Disorders
- Neuroscience and Neural Engineering
- Pain Management and Opioid Use
- Spine and Intervertebral Disc Pathology
- Ion channel regulation and function
- Congenital heart defects research
- Philosophical Thought and Analysis
- Weber, Simmel, Sociological Theory
- Pluripotent Stem Cells Research
- RNA and protein synthesis mechanisms
- Philosophy and Historical Thought
- Cardiac electrophysiology and arrhythmias
- Nietzsche, Schopenhauer, and Hegel
- Neuroscience and Neuropharmacology Research
Italian Institute of Technology
2022-2024
Sapienza University of Rome
2019-2024
Bioprinting techniques use bioinks made of biocompatible non-living materials and cells to build 3D constructs in a controlled manner with micrometric resolution. bioprinted structures representative several human tissues have been recently produced using derived by differentiation induced pluripotent stem (iPSCs). Human iPSCs can be differentiated wide range neurons glia, providing an ideal tool for modeling the nervous system. Here we report neural construct generated bioprinting cortical...
Pathogenic variants in the
ABSTRACT Pathogenic variants in the GNAO1 gene, encoding alpha subunit of an inhibitory heterotrimeric guanine nucleotide-binding protein (Go) highly expressed mammalian brain, have been linked to encephalopathy characterized by different combinations neurological symptoms, including developmental delay, hypotonia, epilepsy and hyperkinetic movement disorder with life-threatening paroxysmal exacerbations. Currently, there are only symptomatic treatments, little is known about pathophysiology...
Excessive Ca
Bone pain typically occurs immediately following skeletal damage with mechanical distortion or rupture of nociceptive fibres. The mechanism is also associated chronic conditions where the healing process impaired. Any load impacting on area fractured bone will increase intraosseous pressure, consequently stimulating response, necessitating rapid clinical intervention to relieve and appropriate mitigation any processes involved loss mass, muscle, mobility and, prevent death. review has...