A5103251388- Pelvic floor disorders treatments
- Hernia repair and management
- Endometrial and Cervical Cancer Treatments
- Anorectal Disease Treatments and Outcomes
- Circadian rhythm and melatonin
- Uterine Myomas and Treatments
- Minimally Invasive Surgical Techniques
- Sleep and related disorders
- Viral Infections and Immunology Research
- Pelvic and Acetabular Injuries
- Diverticular Disease and Complications
- Animal Disease Management and Epidemiology
- Ovarian cancer diagnosis and treatment
- Cancer-related molecular mechanisms research
- Sleep and Wakefulness Research
- Energy Load and Power Forecasting
- Gestational Trophoblastic Disease Studies
- Ectopic Pregnancy Diagnosis and Management
- Cancer Mechanisms and Therapy
- Stock Market Forecasting Methods
- Animal Virus Infections Studies
- Reproductive System and Pregnancy
- Solar Radiation and Photovoltaics
- PI3K/AKT/mTOR signaling in cancer
- Gynecological conditions and treatments
Wuhan Puai Hospital
2025
Obstetrics and Gynecology Hospital of Fudan University
2010-2024
Tianjin University
2023
Kunming Children's Hospital
2020-2022
State Key Laboratory of Oncogene and Related Genes
2021-2022
Kunming Medical University
2020-2022
Health First
2021
Fudan University
2021
Abstract Background To describe the short-term outcomes of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) for uterosacral ligament suspension (USLS) in patients with severe prolapse. Methods This was a retrospective study prolapse (≥ stage 3) who underwent vNOTES USLS between May 2019 and July 2020. The Pelvic Organ Prolapse Quantification (POP-Q) score, Prolapse/Urinary Incontinence Sexual Questionnaire short form (PISQ-12) Floor Inventory-20 (PFDI-20) were used to...
Previous studies by our group revealed that the phosphoinositide 3‑kinase (PI3K)/AKT pathway was involved in estrogen‑induced metastasis ovarian cancer cells. In present study, role and mechanism of invasion further explored using a stable short hairpin RNA (shRNA) estrogen receptor α/β (ER α/β) SKOV3 cell line when ER α β were knocked down lentiviral infection. The effects LY294002, PI3K inhibitor, on shRNA cells evaluated vitro vivo. 17‑β estradiol promoted invasion, activated...
Abstract Aim: To compare the clinical outcomes and associated costs between laparoscopic abdominal surgery for patients with endometrioid endometrial cancer. Methods: From 2003 to 2008, 115 who underwent laparoscopically‐assisted cancers were enrolled in this retrospective study. Another 123 had same histological type of cancer included as control group. The clinico‐pathological variables, surgical outcome, costs, death case recurrence two groups compared. Results: There was no difference...
The aim of our study was to evaluate and compare the differences in clinicopathological variables overall survival (OS) synchronous primary cancers endometrium ovary (SCEO) endometrial cancer with ovarian metastasis (ECOM). In addition, we aimed determine characteristics effective treatments for patients SCEO avoid misdiagnosis overtreatment. A review medical records from January 2009 2017 revealed 111 coexisting carcinoma diagnosed at Obstetrics Gynecology Hospital Fudan University....
The effects of microRNAs (miRNAs/miRs) on glioblastoma have attracted the attention researchers in last 7 years. However, role miR‑640 and its targeted gene, Slit guidance ligand 1 (SLIT1), development are not yet fully understood. present study aimed to investigate proliferation adhesion glioblastoma. Reverse transcription‑quantitative PCR analysis was performed detect SLIT1 expression tissues cells. In addition, Dual‑luciferase reporter RNA‑pull down assays were assess association between...
Abstract Background Sacrocolpopexy is the gold standard treatment for apical prolapse. With development of minimally invasive surgical techniques, new approach transvaginal single-port laparoscopic sacrocolpopexy (TS-LSC) has become available. However, its therapeutic effects remain unclear. The aim this study to compare middle-term clinical outcomes with multi-port (LSC) Methods We conducted a retrospective cohort study. Patients advanced prolapse who underwent either TS-LSC or LSC between...
After vaccination with enterovirus 71 (EV-A71), the prevalence of hand-foot-and-mouth disease (HFMD) remained high, and spatial-temporal distribution enteroviruses changed. Therefore, it is essential to define temporal features, spatial distributions, epidemiological etiological characteristics HFMD in Kunming. Between 2017 2020, a total 36,540 children were diagnosed Kunming, including 32,754 enterovirus-positive clinical samples. Demographic, geographical, data cases acquired analyzed....
Objective To investigate the clinical manifestation, diagnosis, therapies and medical economics of cesarean scar pregnancy (CSP). Methods From Jan. 2005 to Dec. 2008, 96 patients with CSP treated in Obstetrics Gynecology Hospital Fudan University were studied retrospectively. Those cases divided into 3 groups. Thirty-three methotrexate (MTX) 50 mg/m2 intravenously guttae group A. Among that 18 MTX, after 5 - 10 days they underwent dilation curettage uterus; 15 given by first if level serum...
We describe the standard practice of presacral exposure during transvaginal natural orifice transluminal endoscopic surgery (vNOTES) for sacrocolpopexy in women with uterine prolapse. In this video, we demonstrate key techniques: identifying right hypogastric nerve (rHN) before opening pelvic peritoneum; removing fat and loose connective tissue along rHN to expose fascia; incising fascia reach space middle sacral vasculature anterior longitudinal ligament (ALL) first vertebra (S1) below...
Objective To compare the characteristics, surgical complications, and overall survival between patients undergoing laparoscopy versus laparotomy for treatment of early-stage cervical stump carcinoma. Methods Patients with International Federation Gynecology Obstetrics (FIGO, 2009) stage IA2 to IIA2 carcinoma who underwent or in Hospital Fudan University from January 2000 June 2018 were retrospectively reviewed. All patients’ clinical pathological features, follow-up data retrieved. Results...
Abstract Background To introduce a novel technique of transvaginal extraperitoneal single-port laparoscopic sacrocolpopexy (ESLS) for apical prolapse and to evaluate the feasibility short-term outcomes this technique. Methods Sixteen patients were enrolled undergo ESLS between January 2020 May 2021. Perioperative included. Short-term results assessed by Pelvic Floor Distress Inventory-20 (PFDI-20), Organ Prolapse Quantification (POP-Q) scores, mesh exposure recurrence. Results A total 14/16...
The current study aimed to evaluate the clinical outcomes of patients with intravenous leiomyomatosis (IVL) who underwent myomectomy. Clinical data were retrieved from our database January 2001 October 2018. Of 197 IVL, 9 (4.6%) included. patients' age ranged 24 46 (mean: 31.1 ± 7.3) years. Five (55.6%) had not yet given birth upon IVL diagnosis. Three treated gonadotropin-releasing hormone agonists after surgery. average follow-up time was 58.9 27.8 (range: 29-122) months. Four presented...
Abstract Background To describe the short-term outcomes of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) for uterosacral ligament suspension (USLS) in patients with severe prolapse. Methods This is a retrospective study conducted prolapsed (≥stage 3) who underwent vNOTES USLS between May 2019 and July 2020. The Pelvic Organ Prolapse Quantification (POP-Q) score, Prolapse/Urinary Incontinence Sexual Questionnaire short form (PISQ-12) Floor Inventory-20 (PFDI-20) were...
Objective: To examine the association between sleep characteristics and night shift work risk of polycystic ovary syndrome (PCOS) in Chinese women to investigate their relationship with infertility PCOS. Methods: From March 21, 2021 April 31, 2021, 3,927 or without PCOS were recruited online. All participants completed WeChat-based electronic questionnaires. Sleep measured using Pittsburgh quality index. Results: A total 2,871 included final analysis. duration (odds ratio [OR], 0.857; 95%...
Objective To explore the effects of lidocaine on expressions tumor necrosis factor-a (TNF-α) and intercellular adhesion molecule-1 (ICAM-1) in intestines subjected to ischemia/reperfusion (I/R) injury.Methods In this study,48 Sprague-Dawley (SD) rats aged 4 weeks old were randomly divided into 3 groups according their treatment.In I/R group,the abdominal cavity was opened,and intestinal injury induced by 60 minutes' superior mesenteric artery occlusion followed reperfusion for 30 min,60...
<title>Abstract</title> Background Polycystic ovary syndrome (PCOS) is one of the most common risk factors for development uterine corpus endometrial carcinoma (UCEC). Despite mounting evidence suggesting that PCOS was strongly associated with adverse prognosis UCEC, prediction and treatment determination remain exceedingly challenging. Results In this study, we constructed a prognostic signature UCEC predicted potential therapeutic agents patients high score. First, identified key genes...