A5087935552- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Nail Diseases and Treatments
- Plant Pathogens and Fungal Diseases
- Antimicrobial Peptides and Activities
- Plant-Microbe Interactions and Immunity
- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- T-cell and Retrovirus Studies
- Bacterial biofilms and quorum sensing
- Studies on Chitinases and Chitosanases
- Plant-Derived Bioactive Compounds
- Women's cancer prevention and management
- Oral microbiology and periodontitis research
- Infectious Diseases and Mycology
- Plant Disease Resistance and Genetics
- Phytoplasmas and Hemiptera pathogens
- Mycotoxins in Agriculture and Food
- Phytochemical compounds biological activities
- Peptidase Inhibition and Analysis
- Hemostasis and retained surgical items
- Yeasts and Rust Fungi Studies
- Probiotics and Fermented Foods
- Surgical Sutures and Adhesives
- Synthesis and Biological Evaluation
Universidade Estadual Paulista (Unesp)
2016-2025
Universidade Paulista
2024
Centro Universitário de Araraquara
2006-2023
Universidade de Caxias do Sul
2021
University of Aveiro
2021
Fundação Araucária
2021
Instituto de Ciências Farmacêuticas
2000-2017
Instituto Evandro Chagas
2009
Universidade de São Paulo
1997-2009
Instituto Adolfo Lutz
2008
The pathogenic fungus Paracoccidioides brasiliensis causes paracoccidioidomycosis, a pulmonary mycosis acquired by inhalation of fungal airborne propagules, which may disseminate to several organs and tissues, leading severe form the disease. Adhesion invasion host cells are essential steps involved in infection dissemination pathogens. Furthermore, pathogens use their surface molecules bind extracellular matrix components establish infection. Here, we report characterization...
The incidence of opportunistic fungal infections has increased in recent decades due to the growing proportion immunocompromised patients our society. Candida krusei been described as a causative agent disseminated susceptible patients. Although its prevalence remains low among yeast (2–5%), intrinsic resistance fluconazole makes this important from epidemiologic aspects. Non mammalian organisms are feasible models study virulence and drug efficacy. In work we have used lepidopteran Galleria...
Dermatophytes are fungi responsible for a disease known as dermatophytosis. Biofilms sessile microbial communities surrounded by extracellular polymeric substances (EPS) with increased resistance to antimicrobial agents and host defenses. This paper describes, the first time, characteristics of Trichophyton rubrum T. mentagrophytes biofilms. Biofilm formation was analyzed light microscopy, scanning electron microscopy (SEM) confocal laser (CLSM) well staining crystal violet safranin....
The 43,000-molecular-weight (43K) soluble glycoprotein was detected in sera of patients with paracoccidioidomycosis by the immunoblot technique using as probe rabbit monospecific antisera to this fraction. 43K antigen present before treatment acute (juvenile) form; it started disappear from circulation after 10 months chemotherapy, and undetectable 2 years treatment. In chronic cases, without treatment, absent healed cases. detection protein specific Paracoccidioides brasiliensis may be...
Methodology for testing natural compounds determination of antifungal activity had been developed with adaptations. The most used are bioautography and agar diffusion a complex no defined media. In this study, different methods products discussed the use M27-A2 microdilution test from CLSI (Clinical Laboratory Standards Institute, 2002), as general standard methodology plant extracts is recommended.
Candida auris is an emerging fungal pathogen of great concern among the scientific community because it causing increasing number hospital outbreaks difficult management worldwide. In addition, isolates from this species frequently present reduced susceptibility to azole and echinocandin drugs. For reason, necessary develop new antifungal strategies better control disease caused by yeast. work, we screened drugs Prestwick chemical library, which contains 1,280 off-patent compounds that are...
Background Serological tests have long been established as rapid, simple and inexpensive tools for the diagnosis follow-up of PCM. However, different protocols antigen preparations are used few attempts to standardize routine serological methods not succeeded. Methodology/Principal findings We compared performance six Brazilian reference centers Each center provided 30 sera PCM patients, with positive high, intermediate low titers, which were defined "reference" titers. then applied its own...