A5038269333- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and Perinatal Health Interventions
- Pregnancy and preeclampsia studies
- Blood groups and transfusion
- Neonatal Respiratory Health Research
- Parvovirus B19 Infection Studies
- Congenital Diaphragmatic Hernia Studies
- Maternal and fetal healthcare
- Neonatal and fetal brain pathology
- Global Maternal and Child Health
- Fetal and Pediatric Neurological Disorders
- Preterm Birth and Chorioamnionitis
- Tracheal and airway disorders
- Pregnancy-related medical research
- Grief, Bereavement, and Mental Health
- Ectopic Pregnancy Diagnosis and Management
- Infant Development and Preterm Care
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Autopsy Techniques and Outcomes
- Pelvic floor disorders treatments
- Abdominal Trauma and Injuries
- Erythrocyte Function and Pathophysiology
- Hernia repair and management
Mater Research
2013-2023
The University of Queensland
2013-2023
Mater Health Services
2012-2023
Mater Mothers' Hospital
2014-2023
Mater Misericordiae Hospital
2017-2023
University of Exeter
2023
King Edward Memorial Hospital
2023
Griffith University
2022
University of Bristol
2022
Monash University
2022
Fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased postnatal survival among infants severe pulmonary hypoplasia due to isolated congenital diaphragmatic hernia on the left side, but data are lacking inform its effects in moderate disease.
Audit and classification of stillbirths is an essential part clinical practice a crucial step towards stillbirth prevention. Due to the limitations ICD system lack international approach acceptable solution, numerous disparate systems have emerged. We assessed performance six contemporary inform development internationally accepted approach. evaluated following systems: Amended Aberdeen, Extended Wigglesworth; PSANZ-PDC, ReCoDe, Tulip CODAC. Nine teams from 7 countries applied cohorts their...
Congenital diaphragmatic hernia (CDH) is a congenital anomaly with high mortality and morbidity mainly due to pulmonary hypoplasia hypertension. Temporary fetal tracheal occlusion promote prenatal lung growth may improve survival. Entrapment of fluid stretches the airways, leading growth.Fetal endoluminal (FETO) performed by percutaneous sono-endoscopic insertion balloon developed for interventional radiology. Reversal induce maturation can be fetoscopy, transabdominal puncture,...
To assess the effect of maternal sildenafil therapy on fetal growth in pregnancies with early-onset restriction.A randomised placebo-controlled trial.Thirteen maternal-fetal medicine units across New Zealand and Australia.Women singleton affected by restriction at 22+0 to 29+6 weeks.Women were oral administration 25 mg citrate or visually matching placebo three times daily until 32+0 weeks, birth death (whichever occurred first).The primary outcome was proportion an increase velocity....
In a phase 1/2 study, maternal respiratory syncytial virus vaccine candidate (RSVPreF3) demonstrated an acceptable safety profile and efficiently increased RSV-specific humoral immune responses in non-pregnant women.In this 2 observer-blind, placebo-controlled, randomized clinical trial (NCT04126213), the of RSVPreF3 (60 or 120 µg), administered during late second third trimester, was evaluated 213 18- to 40-year-old healthy pregnant women through 6 months postdelivery their offspring...
A carefully classified dataset of perinatal mortality will retain the most significant information on causes death. Such is needed for health care policy development, surveillance and international comparisons, clinical services research. For comparability purposes, we propose a classification system that could serve all these needs, be applicable in both developing developed countries. It to adhere basic concepts underlying cause International Classification Diseases (ICD), although gaps...
Objective This study reviews our clinical experience of non-invasive techniques for early sex determination. It assesses the effectiveness these at reducing invasive prenatal testing X-linked genetic disease or ambiguous development external genitalia. Methods A prospective cohort 30 pregnancies was referred to a tertiary unit diagnosis. Fetal gender determined using two techniques: analysis free fetal DNA (ffDNA) in maternal plasma and ultrasound visualisation. The results were compared by...
ABSTRACT Objective To investigate the antenatal management and outcome in a large international cohort of monochorionic twin pregnancies with spontaneous or post‐laser anemia–polycythemia sequence (TAPS). Methods This study analyzed data diagnosed antenatally TAPS 17 fetal therapy centers, recorded Registry between 2014 2019. Antenatal diagnosis was based on middle cerebral artery peak systolic velocity > 1.5 multiples median (MoM) donor < 1.0 MoM recipient. The following groups were...
Objective: To evaluate a non-invasive molecular test using free circulating fetal DNA in maternal plasma to predict the RHD type. Design: A prospective cohort study. Participants and setting: Venous blood samples were collected from 140 Rhesus (Rh) D-negative women booked for antenatal care two tertiary maternity hospitals Sydney Brisbane between November 2006 April 2008. Cell-free DNA, including was extracted Australian Red Cross Blood Service laboratory, three exon regions of gene...
Abnormally invasive placenta is a major cause of maternal morbidity and mortality. The aim this study was to assess the effectiveness standardized operative approach performed by gynecological oncologists in surgical management abnormally placenta.We retrospective analysis all cases morbid placental adherence managed at Mater Mothers' Hospitals, Brisbane, Australia between January 2000 June 2013. A standard involving extensive retro-peritoneal bladder dissection before delivery fetus,...
The National Health and Medical Research Council (NHMRC) Centre of Excellence in Stillbirth the Perinatal Society Australia New Zealand (PSANZ) have recently partnered updating an important clinical practice guideline, Care pregnant women with decreased fetal movements . This guideline offers 12 recommendations a suggested care pathway, aim to improve quality for reporting through evidence‐based approach. Adoption by clinicians maternity hospitals could result earlier identification...
Stillbirths and neonatal deaths are devastating events for both parents clinicians global public health concerns. Careful clinical management after these is required, including appropriate investigation assessment to determine cause (s) prevent future losses, improve bereavement care families. An educational programme professionals working in maternal child has been designed address needs according the Perinatal Society of Australia New Zealand Guideline Mortality: IMproving mortality Review...
BackgroundTwin anemia polycythemia sequence is a chronic form of unbalanced fetofetal transfusion through minuscule placental anastomoses in monochorionic twins, leading to the donor and recipient. Owing low incidence twin sequence, data on diagnosis, management, outcome are limited.ObjectiveThis study aimed investigate large international cohort spontaneous sequence.Study DesignData from registry, retrospectively collected between 2014 2019, were used for this study. A total 17 fetal...
A survey of the waiting times and patients' opinions these was undertaken in a busy district general hospital A&E department. The various components overall time are analysed specific points attendance, where were prolonged, identified. Standards derived which is hoped may result 75% patients being satisfied with duration their wait. current levels achievement compared standards. Suggested actual improvements to department improve our performance described.
Background: Decreased fetal movement (DFM) is associated with increased risk of adverse pregnancy outcome. However, there limited research to inform practice in the detection and management DFM. Aims: To identify current practices views obstetricians Australia New Zealand regarding Methods: A postal survey Fellows Members, obstetric trainees Royal Australian College Obstetricians Gynaecologists. Results: Of 1700 surveys distributed, 1066 (63%) were returned, these, 805 (76% responders)...
To report the perinatal outcomes of a large series twin pregnancies with severe twin-twin transfusion syndrome (TTTS) managed laser ablation surgery in an Australian tertiary centre and to compare outcome other cohorts.The 100 consecutive TTTS selective fetoscopic from March 2002 June 2007 were examined. Survival neonatal morbidity analysed. Comparisons made results studies at least pregnancies.There women treated ablation; 34 stage II, 44 III 22 IV. Median gestation time was 21 weeks (range...
Abstract Objective This study was carried out to evaluate the perinatal outcomes of pregnancy with pregestational diabetes mellitus complicated by polyhydramnios. Methods a retrospective singleton pregnancies, an antepartum diagnosis polyhydramnios, seen at maternal fetal medicine department Mater Mothers' Hospital, tertiary‐level facility. All pregnancies in women beyond 24 weeks gestation, from 1996 2006, were reviewed ( n = 314), and polyhydramnios identified 59). Pregnancy whose compared...