A5101644660- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Carbohydrate Chemistry and Synthesis
- Immune Cell Function and Interaction
- Synthesis and biological activity
- Molecular Sensors and Ion Detection
- Glycosylation and Glycoproteins Research
- Cancer, Hypoxia, and Metabolism
- Animal Disease Management and Epidemiology
- Viral Infections and Immunology Research
- Phytase and its Applications
- Head and Neck Cancer Studies
- Synthesis and Biological Evaluation
- Diagnosis and treatment of tuberculosis
- Advanced Chemical Sensor Technologies
- Click Chemistry and Applications
- Phytoestrogen effects and research
- Semiconductor Lasers and Optical Devices
- Proteins in Food Systems
- Forest, Soil, and Plant Ecology in China
- Salivary Gland Tumors Diagnosis and Treatment
- Electrochemical Analysis and Applications
- T-cell and Retrovirus Studies
- Antibiotic Resistance in Bacteria
- Research in Cotton Cultivation
Zhejiang University
2022
First Affiliated Hospital Zhejiang University
2022
National Clinical Research Center for Digestive Diseases
2022
Chinese PLA General Hospital
2022
Fuzhou University
2017-2020
The 309th Hospital of Chinese People's Liberation Army
2015-2017
Guizhou University
2016
Tumor Hospital of Xinjiang Medical University
2008
CAE (Canada)
2006
Leibniz Institute for Jewish History and Culture – Simon Dubnow
2001
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and Evaluation of Homoaza Sugars as Glycosidase InhibitorsChi-Huey Wong, Louis Provencher, John A. Porco Jr., Sang-Hun Jung, Yi-Fong Wang, Lihren Chen, Ruo Darryl H. SteensmaCite this: J. Org. Chem. 1995, 60, 6, 1492–1501Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/jo00111a007https://doi.org/10.1021/jo00111a007research-articleACS...
This paper describes our recent study of glycosyl phosphites for glycosylation reactions, with particular emphasis on the investigation protecting group and stereochemistry effects anomeric reactivity stereoselectivity, application this methodology to synthesis Lewis X (Lex), Y (Ley), glycopeptides, sialyl (SLex) mimetics. Both α-O-fucosyl-l-threonine α-O-fucosyl-(1R,2R)-2-aminocyclohexanol were found be effective templates chemical/enzymatic SLex mimetics, some fucopeptides prepared 5−10...
An efficient Brønsted base-catalyzed Pechmann-type reaction of cyclic 1,3-diones with ethyl 4,4,4-trifluoroacetoacetate to afford 4-trifluoromethyl 2-pyrones and pyridones was developed.
We report herein the design, synthesis, and in vitro anti‐tumor activities of a series 1,2,3‐triazole‐tetraethylene glycol tethered heteronuclear bis‐Schiff base derivatives isatin. Our results indicated that all synthesized bases except 9e showed considerable anticancer against HepG2, Hela, HCT‐116, A549, MCF‐7 human cancer cell lines with IC 50 range 9.79–48.75 μM were more potent than etoposide A549 lines. In particular, most 9g (IC : 9.79–29.64 μg/mL) was highly active five tested, could...
Fourteen benzofuran–isatin hybrids 6a – f and 7a h tethered via alkyl linker (pentylene hexylene) were designed synthesized, 6c screened for their in vitro anticancer activity against various human cancer cell lines. The majority of the active tested cells, most 7g (half maximal inhibitory concentration/IC 50 : 77.2–88.9 μM) 7h (IC 65.4–89.7 μM), which possessed broad spectrum as potent reference vorinostat 64.2–>100 all lines, could act leads further investigations. structure–activity...
Background Organoids, which enable disease modeling and drug screening closer to an in vivo environment, can be isolated grown from organs such as the brain, small intestine, kidney, lungs, liver. To facilitate establishment of liver intestinal organoids, we developed efficient protocols for cholangiocytes intestine crypts collecting organoid culturing. Methods Cholangiocytes were collected intrahepatic bile ducts, gallbladder, by gravity settling multistep centrifugation methods. The cells...
Two colorimetric sensors, derived from pentaerythrityltetramine and salicylaldehyde ( 1 ) or o -vanillin 2 ), had been synthesized. Both sensors showed selective sensing ability for Fe (Ⅱ) (Ⅲ) by changing color light yellow to either orange purple when immersed in water samples. The coordinated with 1:1 stoichiometry, as has confirmed the results of LC-MS spectrometry UV-Vis spectrum titration. detection limits (0.19 μmol·L -1 (0.21 are lower than WHO guideline (5 drinking water.
The aim of this study was to prepare a stable oil-in-water emulsion by whey powder (WP)–maltodextrin (MD) at room temperature for further industrial processing. Due the weak surface activity WP and MD, diacetyl tartaric acid ester monoglycerides (DATEM) added system as an emulsifier effect DATEM concentration on properties WP–MD emulsions investigated. As increased, mean droplet size, zeta potential, tension, apparent viscosity, morphology changed significantly. Fourier transform infrared...