Alessandro Morellato

ORCID: 0000-0002-8267-9744
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About
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Research Areas
  • Lipid metabolism and biosynthesis
  • Lipoproteins and Cardiovascular Health
  • Cancer, Lipids, and Metabolism

University of Turin
2023

Abstract p140Cap is an adaptor protein involved in assembling multi-protein complexes regulating several cellular processes. acts as a tumor suppressor breast cancer (BC) and neuroblastoma patients, where its expression correlates with better prognosis. The role of metabolism remains largely unknown. Here we study the modulation mevalonate (MVA) pathway BC cells. MVA responsible for biosynthesis cholesterol non-sterol isoprenoids often deregulated cancer. We found that both vitro vivo, cells...

10.1038/s41419-023-06357-z article EN cc-by Cell Death and Disease 2023-12-20
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