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Research Areas
- Lipid metabolism and biosynthesis
- Lipoproteins and Cardiovascular Health
- Cancer, Lipids, and Metabolism
University of Turin
2023
Abstract p140Cap is an adaptor protein involved in assembling multi-protein complexes regulating several cellular processes. acts as a tumor suppressor breast cancer (BC) and neuroblastoma patients, where its expression correlates with better prognosis. The role of metabolism remains largely unknown. Here we study the modulation mevalonate (MVA) pathway BC cells. MVA responsible for biosynthesis cholesterol non-sterol isoprenoids often deregulated cancer. We found that both vitro vivo, cells...
10.1038/s41419-023-06357-z
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Cell Death and Disease
2023-12-20
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