A5035322630- Cystic Fibrosis Research Advances
- Neonatal Respiratory Health Research
- Pediatric health and respiratory diseases
- Connective tissue disorders research
- Pancreatitis Pathology and Treatment
- Pulmonary Hypertension Research and Treatments
- Tracheal and airway disorders
- Gastrointestinal disorders and treatments
- Antifungal resistance and susceptibility
- Ovarian function and disorders
- Infant Nutrition and Health
- Pneumonia and Respiratory Infections
- Liver Disease and Transplantation
- Healthcare Systems and Public Health
- Adolescent and Pediatric Healthcare
- Antibiotic Resistance in Bacteria
- Genetic and Kidney Cyst Diseases
- Enterobacteriaceae and Cronobacter Research
- Child Nutrition and Feeding Issues
- Pediatric Hepatobiliary Diseases and Treatments
- Medical and Biological Sciences
- Nematode management and characterization studies
- Bone health and osteoporosis research
- Legume Nitrogen Fixing Symbiosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Russian Children's Clinical Hospital
2018-2024
Pirogov Russian National Research Medical University
2020-2023
Moscow Power Engineering Institute
2020
Moscow Aviation Institute
2020
In current literature there are only scarce data on the host inflammatory response during Burkholderia cepacia complex (Bcc) persistence. The primary objective of present research was to carry out cross-sectional analyses biomarkers and evaluate disease progression in cystic fibrosis (CF) patients with chronic Bcc infection pathogen-free ones. secondary aim assess prospectively overall survival study participants up 8 years follow-up. included 116 paediatric CF; 47 CF were chronically...
Study Objective: To determine in vitro activity of Tobramycin for Pseudomonas aeruginosa spp. isolated children with cystic fibrosis (CF); to retrospectively study the efficiency dynamics inhalative management bronchopulmonary process exacerbation CF aged 9 years old (2009–2018). Design: retrospective analysis. Materials and Methods. The included 173 3 17 old; median age general group was 11 [8; 15] years. Subjects were divided into two comparison groups, depending on various 14-day combined...
The aim of the study was to determine clinical and genetic features syndrome undifferentiated connective tissue dysplasia (CTD) in cystic fibrosis (CF) children possible modifying effect polymorphisms genes on development severe pathology bronchopulmonary system CF cases. 188 patients with moderate course СF, aged from 3 17 years were examined. In СF significant associations have been established between matrix metalloproteinase 3, phenotypic signs CTD respiratory disorders.
This review is devoted to an urgent and insufficiently studied problem - the characteristics of pubertal development girls with cystic fibrosis (CF), deviations in period menarche, stages puberty, anatomical physiological features female reproductive system this monogenic disease. The increase life expectancy, as well spread increasing availability targeted therapies, highlight need for further research on topic. Early diagnosis disorders due timely prescribed therapy (hormonal) allows not...
Connective tissue dysplasia is congenital anomaly manifesting as different organ's and system's alterations: locomotor, skin, visceral dysfunctions. This article presents literature review covering such topical issues female reproductive system features affected by mesenchymal pathology (undifferentiated forms of connective dysplasia) its medicamentous management (microelements, hormonal drugs, adaptogens). The analysis original studies on this topic has revealed that significant effect...
The article considers the issue of cystic fibrosis – a monogenic autosomal recessive disease. It describes history CFTR gene discovery, further search for modifier genes to explain variability clinical manifestations fibrosis. review discusses problems connective tissue dysplasia and somatic pathology, which is formed due dysmorphogenesis in patients with fibrosis; also contains justification connection between formation severe lungs liver presence genetic markers dysplasia. author assumes...
A rare clinical case of the development acute pancreatitis in adolescents with a mixed form cystic fibrosis having “mild genotype” disease (“mild mutation” CFTR gene) and simultaneously presence fibrosis-associated liver cirrhosis this patient is described. Such combination extremely observed cases “mild” mutations gene.
Представлена клиническая характеристика и описание фенотипа детей с муковисцидозом, а также новые генетические варианты в гене CFTR, выявленные результате проведения NGS секвенирования. Ключевые слова: муковисцидоз,