A5059660148- Cystic Fibrosis Research Advances
- Pediatric health and respiratory diseases
- Infections and bacterial resistance
- Bacterial biofilms and quorum sensing
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Pneumonia and Respiratory Infections
- Nosocomial Infections in ICU
- Inhalation and Respiratory Drug Delivery
- Mycobacterium research and diagnosis
- Diphtheria, Corynebacterium, and Tetanus
- Streptococcal Infections and Treatments
- Respiratory viral infections research
- Antimicrobial Resistance in Staphylococcus
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial Metabolism and Applications
- Tracheal and airway disorders
- Leech Biology and Applications
- Bartonella species infections research
- Maternal Mental Health During Pregnancy and Postpartum
- COVID-19 Impact on Reproduction
- Reproductive System and Pregnancy
- Bacillus and Francisella bacterial research
- Intramuscular injections and effects
- Neonatal and Maternal Infections
City Clinical Hospital No15 named. O. M. Filatova
2016-2023
City Clinical Hospital
2010-2020
Carbapenem-nonsusceptible (Carba-NS) Acinetobacter baumannii has emerged as an important cause of nosocomial infections. In the present study, we characterized 91 Carba-NS A. isolates collected from patients surgical departments and intensive care units at three hospitals in Moscow 2012-2015. Multilocus sequence typing (MLST) using Oxford (Oxf) scheme identified 16 types (STs) clonal complexes (CCs), including CC92Oxf (67%), CC109Oxf (1%), CC944Oxf (29%), singleton ST1100Oxf (3%). was...
The problem of timely diagnosis and proper management patients with cystic fibrosis is crucial not only in our country, but throughout the world. Experts Union Pediatricians Russia have considered various issues etiology, pathogenesis, epidemiology, diagnosis, treatment this genetic disease a modern light. Particular attention was paid to screening methods for early fibrosis. principles complex therapy were justified, including rational use antibacterial mucolytic drugs enzyme replacement...
Chronic lower respiratory tract infection in patients with cystic fibrosis (CF) is the major factor determining severity of clinical course and prognosis disease. The purpose study was to investigate prevailing microflora CF changes activity antibacterial medicines (ABM) during period 2000–2015 order optimize guidelines for antibiotic therapy. Bronchial secretion evaluated from 2000 till 2015. 9774 samples were studied, 16.703 microbial strains obtained. In 2000–2015, P. aeruginosa (smooth...
Stenotrophomonas maltophilia is a common opportunistic microorganism and an important respiratory pathogen in cystic fibrosis (CF). The aim of this study was to determine antimicrobial resistance phenotypes, sequence-types (ST) genetic determinants antibiotic S. strains recovered from CF patients Russia. isolates 170 were analyzed. Minimum inhibitory concentrations antibacterial agents determined using Sensititre Gram Negative GNX2F plates the results interpreted according Clinical...
The aim of this study was to characterize chronic respiratory infection in cystic fibrosis (CF) patients Russia according the National Russian CF Register. Methods. Register included 2,131 from 74 regions (2,092 alive and 39 died patients) 2014 (the median age, 10.2 (15.2) years; 29.2% were adults ≥ 18 лет). Microbiological findings (chronic caused by Staphylococcus aureus, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Burkholderia cepacia соmplex, non-tuberculous mycobacteria (NTM),...
Cystic fibrosis (CF) is a common genetic disease, manifested by airway obstruction and chronic respiratory infection. The most prevalent infectious agent in airways of CF patients Pseudomonas aeruginosa. This study aimed to determine sequence-types, antimicrobial resistance phenotypes genes defining adaptive antibiotic P. aeruginosa isolates recovered from Russia. In total, 84 strains 64 were analyzed. Susceptibility antibiotics was determined disk diffusion test. Whole-genome sequencing...
Детская Городская Больница Святой Ольги,
Study Objective: To determine in vitro activity of Tobramycin for Pseudomonas aeruginosa spp. isolated children with cystic fibrosis (CF); to retrospectively study the efficiency dynamics inhalative management bronchopulmonary process exacerbation CF aged 9 years old (2009–2018). Design: retrospective analysis. Materials and Methods. The included 173 3 17 old; median age general group was 11 [8; 15] years. Subjects were divided into two comparison groups, depending on various 14-day combined...
The aim of this study was to evaluate prevalence chronic rhinosinusitis (CRS) and nasal polyps in adult patients with cystic fibrosis (CF) Russian Federation. Additionally, we investigated the clinical course CRS developed optimal therapeutic strategy. Methods . Three hundred forty eight CF were involved study. Physical examination, computed tomography (CT) paranasal sinuses audiometry, if needed, used. bilateral diagnosed 28 patients. Nasal endoscopy, SNOT-20 questionnaire, rhinomanometry,...
Российский национальный исследовательский медицинский университет им.Н. И