- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Pneumonia and Respiratory Infections
- Urinary Tract Infections Management
- Antibiotics Pharmacokinetics and Efficacy
- Escherichia coli research studies
- Probiotics and Fermented Foods
- Infections and bacterial resistance
- Brucella: diagnosis, epidemiology, treatment
- Antifungal resistance and susceptibility
- Nosocomial Infections in ICU
- Oral microbiology and periodontitis research
- Fungal Infections and Studies
- Vibrio bacteria research studies
- Burkholderia infections and melioidosis
- Bone Tissue Engineering Materials
- Linguistics and Cultural Studies
- Biochemical and Structural Characterization
- Rabies epidemiology and control
- Pharmaceutical and Antibiotic Environmental Impacts
- Cannabis and Cannabinoid Research
Hacettepe University
2009-2022
Hacettepe University Hospital
2020
Office of Infectious Diseases
2009
Background. Pre-term birth and/or low weight (PTLBW) is a serious problem in developing countries. The absence of known risk factors ∼ 50% PTLBW cases has resulted continued search for other causes. aim this study was to examine the effect periodontitis on pregnancy outcomes. Methods. Samples were taken from 50 pregnant women who underwent amniocentesis. Polymerase chain reaction performed amniotic fluid samples obtained during amniocentesis and subgingival plaque determine presence...
Data are presented from the Survey of Antibiotic Resistance (SOAR) for respiratory tract infection pathogens collected in 2011-13 Turkey.MICs were determined using Etest(®). Susceptibility was assessed CLSI, EUCAST and pharmacokinetic/pharmacodynamic (PK/PD) interpretive criteria.Rates antibiotic susceptibility very low among 333 isolates Streptococcus pneumoniae tested: penicillin 38% CLSI (oral) breakpoints; erythromycin 51% criteria; cefuroxime 64.6% PK/PD 46.9% EUCAST. Of isolates, >90%...
Abstract Background: On February 19, 2003, four patients (patients 1-4) in the neurology ward underwent cranial magnetic resonance angiography (MRA) and developed fever within 1 hour afterward. Klebsiella oxytoca was isolated from blood cultures of through 3. Objective: To identify source this cluster nosocomial K. bloodstream infections. Design: Outbreak investigation. Setting: A 1,000-bed university hospital. Methods: The infection control team reviewed patient charts interviewed nursing...
Viridans streptococci are still under investigation concerning epidemiology, pathogenesis and clinical presentations. We aimed to investigate the presentations outcomes of pediatric patients infected with Streptococcus mitis/oralis. Based on accumulation bloodstream infections (BSI) caused by S. mitis/oralis in 4 our Hematology Bone Marrow Transplantation Department at a particular time, review medical microbiological records positive blood cultures for entire hospital was performed. In...
AbstractA multicenter antimicrobial surveillance program was established in Turkey 1995 to monitor the predominant Gram-negative pathogens from intensive care units (ICUs) and resistance patterns of these isolates. Sixteen hospitals participated study a total 1479 isolates 1100 patients were collected. The tested for their susceptibility against 13 antibiotics by E-test method. Minimum inhibitory concentrations (MICs) each isolate determined imipenem, ceftazidime, cef-tazidime-clavulanate,...
To determine antibiotic susceptibility of Streptococcus pneumoniae and Haemophilus influenzae isolates from community-acquired respiratory tract infections (CA-RTIs) collected in 2015-17 Turkey.MICs were determined by CLSI broth microdilution was assessed using CLSI, EUCAST (dose-specific) pharmacokinetic/pharmacodynamic (PK/PD) breakpoints.A total 179 S. 239 H. collected. Few (27.9%) pneumococci penicillin susceptible oral or low-dose breakpoints, but high-dose IV breakpoints 84.4%...
Invasive aspergillosis (IA) presents a diagnostic and therapeutic dilemma for the physicians who take care of patients with severe underlying diseases immunosuppression. This study aimed to evaluate usefulness serum galactomannan (GM) measurements in routine practice surveillance IA along possible caveats diagnosis treatment. Adult high-risk haematological malignancies admitted Internal Medicine wards during 2-year period were followed up by daily visits vital signs, existing or newly...
Lactobacilli are part of the microbiota and also used as probiotics. However, in recent years they have been associated with invasive infections, especially bacteremia. Lactobacillus spp. usually susceptible to penicillins, macrolides, carbapenems, but rhamnosus is intrinsically resistant glycopeptides. The aim this study was determine antimicrobial susceptibility profile resistance mechanism a clinical isolate L. isolated from 10 sets blood cultures same patient. identified by...
Background/aim: The increasing prevalence and global spread of difficult-to-treat carbapenem-resistant Acinetobacter baumannii has become a serious problem. aim this study is to investigate the resistance patterns tigecycline sensitivity A. strains. Materials methods: strains that were collected mainly from intensive care units included into study. antibiotic sensitivity/resistance other antibiotics noted. Presence blaOXA-23, blaOXA-48, blaOXA58, NDM-1 was investigated by PCR. Results: In...
Aim: Nosocomial infections due to methicillin resistant Staphylococcus aureus (MRSA) are an important problem with limited therapeutic options. The aim of this study was determine the vancomycin, teicoplanin, linezolid, tigecycline, erythromycin, gentamicin, ciprofloxacin, rifampin, trimethoprim/sulfamethoxazole, and clindamycin susceptibility, inducible macrolide-lincosamide-streptogramin B (iMLS_B) resistance, clonal diversity patterns 109 mecA positive strains isolated from patients...
Abstract Vancomycin-resistant enterococcus (VRE) is a global threat to public health. Knowledge about the occurrence of van A-carrying enterococci in broiler and environmental samples important as antibiotic resistance can be transferred human bacteria. The aim this study was investigate presence VRE cloacal (house) genotype isolates. In study, 350 swabs were collected from farms. All plated onto selective agar containing 6 mg/L vancomycin 64 ceftazidime. Minimum inhibitory concentration...