A5043330844- Genetic Mapping and Diversity in Plants and Animals
- Gene expression and cancer classification
- Legume Nitrogen Fixing Symbiosis
- Genetics and Plant Breeding
- Plant-Microbe Interactions and Immunity
- Nematode management and characterization studies
- Agronomic Practices and Intercropping Systems
- Plant nutrient uptake and metabolism
- Network Security and Intrusion Detection
- Internet Traffic Analysis and Secure E-voting
- Advanced Malware Detection Techniques
- Genetic and phenotypic traits in livestock
- Bioinformatics and Genomic Networks
- Plant Stress Responses and Tolerance
- Plant Gene Expression Analysis
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Peroxisome Proliferator-Activated Receptors
- Genomics and Chromatin Dynamics
- RNA modifications and cancer
University of Nebraska–Lincoln
2020-2024
Guangzhou University
2022-2023
Qiqihar University
2023
First Affiliated Hospital of Hebei Medical University
2021
Hebei Medical University
2021
Abstract Mapping genotype to phenotype is an essential topic in genetics and genomics research. As the Omics data become increasingly available, 2-variable methods have been widely applied associate with (genome-wide association study), gene expression (transcriptome-wide expression. However, signals detected by these suffer from low mapping resolution or inexplicit causality between phenotype, making it challenging interpret validate molecular mechanisms of underlying genomic variations...
Abstract Beneficial interactions with microorganisms are pivotal for crop performance and resilience. However, it remains unclear how heritable the microbiome is respect to host plant genotype what extent genetic mechanisms can modulate plant-microbe in face of environmental stress. Here, we surveyed root rhizosphere 129 accessions locally adapted Zea mays , sourced from diverse habitats grown under control different stress conditions. We quantified treatment effects on microbiome. Plant...
ABSTRACT Crop improvement, as a long-term endeavor, requires continuous innovations in technique from multiple perspectives. Doubled haploid (DH) technology for pure inbred production, which shaves years off of the conventional selfing approach, has been widely used breeding. However, final success rate vivo maternal DH production is determined by four factors: haploids induction, identification, chromosome doubling, and successful fertile plants to produce seeds. Traits each these steps, if...
Mapping genotype to phenotype is an essential topic in genetics and genomics research. As the Omics data become increasingly available, genome-wide association study (GWAS) has been widely applied establish relationship between phenotype. However, signals detected by GWAS usually span broad genomic regions with many underneath candidate genes, making it challenging interpret validate molecular functions of genes. Under context research, we hypothesized a causal chain from partially mediated...
Owing to cold resistance and a lack of heat in spinach (Spinacea oleracea L.), is the primary constraint that limits its production summer. This study examined auxiliary effects rhizosphere microbes on improving spinach. A strain isolated from soil heat-stressed was identified as Bacillus subtilis designated B. BE-L21. It produces indoleacetic acid, amylase, protease solubilizes phosphorus. Further research revealed seedlings inoculated with this had increased content soluble protein, sugar,...
With the widespread popularity of smart home devices and emergence integration platforms such as Google, Amazon, Xiaomi, industry is in a stage vigorous development. While homes provide users with convenient intelligent living, problem leaking user privacy has become increasingly prominent. Smart give ability to remotely control devices, but they also reflect activities traffic data, which brings risk leaks. Potential attackers can use classification technology analyze characteristics during...
Abstract Root-associated microbiomes in the rhizosphere (rhizobiomes) are increasingly known to play an important role nutrient acquisition, stress tolerance, and disease resistance of plants. However, it remains largely unclear what extent these rhizobiomes contribute trait variation for different genotypes if their inclusion genomic selection protocol can enhance prediction accuracy. To address questions, we developed a microbiome-enabled method that incorporated host SNPs amplicon...
Abstract To leverage the advancements in genome-wide association studies (GWAS) and quantitative trait loci (QTL) mapping for traits molecular phenotypes to gain mechanistic understanding of genetic regulation, biological researchers often investigate expression QTLs (eQTLs) that colocalize with QTL or GWAS peaks. Our research is inspired by 2 such studies. One aims identify causal single nucleotide polymorphisms are responsible phenotypic variation whose effects can be explained their...
As more and smart devices are deployed in homes, the communication between these home elastic computing services may face some risks of privacy disclosure. Different device events (such as camera on, video etc.) will generate different data traffic during communication. However, current system lacks monitoring events, which cause disclosure private collected by devices. In this paper, we present our event monitor system, HomeMonitor. HomeMonitor runs OpenWRT supports complete for HomeMoitor...
Abstract Root-associated microbiomes in the rhizosphere (rhizobiomes) are increasingly known to play an important role nutrient acquisition, stress tolerance, and disease resistance of plants. However, it remains largely unclear what extent these rhizobiomes contribute trait variation for different genotypes if their inclusion genomic selection (GS) protocol can enhance prediction accuracy. To address questions, we developed a microbiome-enabled GS (MEGS) method that incorporated host SNPs...
Abstract Beneficial interactions with microorganisms are pivotal for crop performance and resilience. However, it remains unclear how heritable the microbiome is respect to host plant genotype what extent genetic mechanisms can modulate plant-microbe in face of environmental stress. Here, we surveyed 3,168 root rhizosphere samples from 129 accessions locally adapted Zea mays, sourced diverse habitats grown under control different stress conditions. We quantified treatment effects on...
Abstract High dimensional mediation analysis has been receiving increasing popularity, largely motivated by the scientific problems in genomics and biomedical imaging. Previous literature primarily focused on mediator selection for high mediators. In this paper, we aim at estimation inference of overall indirect effect exposures We propose MedDiC, a novel debiased estimator based difference-in-coefficients approach. evaluate proposed method using intensive simulations find that MedDiC...