Chenxu Liu

ORCID: 0000-0003-0618-881X
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About
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Research Areas
  • Chromosomal and Genetic Variations
  • Plant tissue culture and regeneration
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant Virus Research Studies
  • CRISPR and Genetic Engineering
  • Pharmacological Effects of Natural Compounds
  • Plant Stress Responses and Tolerance
  • Genetics and Plant Breeding
  • Plant Reproductive Biology
  • Wheat and Barley Genetics and Pathology
  • Genetic and phenotypic traits in livestock
  • Epigenetics and DNA Methylation
  • Plant Gene Expression Analysis
  • Spectroscopy and Chemometric Analyses
  • Cancer-related molecular mechanisms research
  • Rheumatoid Arthritis Research and Therapies
  • Plant Disease Resistance and Genetics
  • Medicinal Plant Pharmacodynamics Research
  • Ginseng Biological Effects and Applications
  • Inflammatory Bowel Disease
  • Plant and animal studies
  • RNA modifications and cancer
  • Microscopic Colitis
  • Soil and Water Nutrient Dynamics
  • Soybean genetics and cultivation

Shandong Agricultural University
2024-2025

Zhengzhou University
2024-2025

Guangzhou University of Chinese Medicine
2025

Yangzhou University
2024

China Agricultural University
2014-2024

Hebei University of Chinese Medicine
2023-2024

Second Hospital of Shandong University
2024

Shanghai Clinical Research Center
2024

Sanya University
2022-2023

Nantong University
2021-2023

Doubled haploid technology has been widely applied to multiple plant species and is recognized as one of the most important technologies for improving crop breeding efficiency. Although mutations in MATRILINEAL/Zea mays PHOSPHOLIPASE A1/NOT LIKE DAD (MTL/ZmPLA1/NLD) Zea DOMAIN OF UNKNOWN FUNCTION 679 MEMBRANE PROTEIN (ZmDMP) have shown generate haploids maize, knowledge genetic basis induction (HI) remains incomplete. Therefore, cloning new genes underlying HI further elucidating its...

10.1038/s41477-021-01037-2 article EN cc-by Nature Plants 2021-12-09

Tomato (Solanum lycopersicon) is the second largest vegetable crop and fruit (Costa Heuvelink, 2018). Progress in tomato breeding has been achieved by classical breeding, introgression of traits found related wild Solanum species exploiting heterosis F1 hybrid crosses (Lin et al., 2014). These approaches require development inbred lines to reduce or largely eliminate heterozygosity. Classically, multiple rounds selfing backcrossing are used generate (Gale, 1980), but homozygous can also be...

10.1111/pbi.13755 article EN Plant Biotechnology Journal 2021-12-01

Summary Natural variations in cis ‐regulatory regions often affect crop phenotypes by altering gene expression. However, the mechanism of how promoter mutations expression and stress tolerance is still poorly understood. In this study, analyzing RNA‐sequencing (RNA‐Seq) data reverse transcription quantitative real‐time PCR validation cultivated tomato its wild relatives, we reveal that transcripts WRKY33 are almost unchanged cold‐sensitive Solanum lycopersicum L. ‘Ailsa Craig’ but...

10.1111/nph.18403 article EN New Phytologist 2022-07-27

Doubled haploid (DH) technology is used to obtain homozygous lines in a single generation, technique that significantly accelerates the crop breeding trajectory. Traditionally, vitro culture generate DHs, but this limited by species and genotype recalcitrance. In vivo induction (HI) through seed widely efficiently maize was recently extended several other crops. Here we show HI can be triggered mutation of DMP maternal inducer genes allopolyploid (allotetraploid) Brassica napus Nicotiana...

10.1111/jipb.13244 article EN cc-by-nc Journal of Integrative Plant Biology 2022-03-06

Summary In vivo haploid induction has been extended from maize to monocotyledonous plants like rice, wheat, millet and dicotyledonous such as tomato, rapeseed, tobacco cabbage. Accurate identification of haploids is a crucial step doubled technology, where useful marker very pivotal. R1‐nj an extensively used visual for in maize. RFP eGFP have shown be feasible identifying haploid. However, these methods are either limited specific species, or require equipment. It still lacks efficient that...

10.1111/pbi.14071 article EN cc-by-nc Plant Biotechnology Journal 2023-05-17

SUMMARY In higher plants, the generation and release of viable pollen from anthers is vital for double fertilization initiation seed development. Thus, characterization genes related to development anther dehiscence in plants great significance. The F‐box protein COI1 plays a crucial role jasmonate (JA) signaling pathway interacts with many JAZ family proteins presence jasmonoyl‐isoleucine (JA‐Ile) or coronatine (COR). mutation AtCOI1 Arabidopsis leads defective male sterility (MS), although...

10.1111/tpj.15708 article EN The Plant Journal 2022-02-15

Reinventing the tetraploid potato into a seed-propagated, diploid, hybrid would significantly accelerate breeding. In this regard, development of highly homozygous inbred lines is prerequisite for breeding potatoes, but self-incompatibility and inbreeding depression present challenges developing pure lines. To resolve impediment, we developed doubled haploid (DH) technology, based on mutagenesis DOMAIN OF UNKNOWN FUNCTION 679 membrane protein (StDMP) gene. Here, show that deficiency in StDMP...

10.1007/s42994-022-00080-7 article EN cc-by aBIOTECH 2022-09-15

Because of their high efficiency during chromosome doubling, immature haploid maize (Zea mays L.) embryos are useful for doubled production. The R1-nj marker is commonly used in breeding and has improved the identification. However, its effectiveness limited by genetic background environmental factors. We addressed this technical challenge developing an efficient accurate embryo identification through co-expression two transcription factor genes (ZmC1 ZmR2) driven embryo-aleurone-specific...

10.1111/tpj.15888 article EN cc-by-nc-nd The Plant Journal 2022-07-06

In vivo doubled-haploid technology is widely applied in commercial maize breeding programs because of its time-saving and cost-reducing features. The production haploids primarily depends on the use Stock6-derived haploid inducer lines. Although gene underlying induction, MTL/ZmPLA1/NLD, was cloned recently, mechanism induction still unknown. Hetero-fertilization can occur via a single fertilization, which provides means to investigate single-fertilization events by studying...

10.1093/jxb/ery177 article EN cc-by Journal of Experimental Botany 2018-05-09

Abstract Background Therapeutic options for ulcerative colitis (UC) have increased since the introduction of biologics a few decades ago. Due to wide range available, physicians difficulty in selecting and do not know how balance best drug between clinical efficacy safety. This study aimed compare safety treating colitis. Methods In this study, eight electronic databases (PubMed, Web Science, Cochrane, Embase, Sinomed, China National Knowledge Infrastructure, Chongqing VIP Information,...

10.1186/s12876-023-02938-6 article EN cc-by BMC Gastroenterology 2023-10-06

ABSTRACT Ubiquitin‐mediated proteolysis is a crucial mechanism in plant defenses against pathogens. However, the role of E3 ubiquitin ligases maize ( Zea mays ) defense response Rhizoctonia solani , major soil‐borne fungal pathogen that causes banded leaf and sheath blight, remains unclear. We previously identified ZmPUB19 gene, which encodes U‐box ligase upregulated upon R. infection, suggesting its potential involvement responses. In this study, we established positively influences to ....

10.1111/pce.15407 article EN Plant Cell & Environment 2025-01-31

Abstract Background The association between periodontitis (PT) and rheumatoid arthritis (RA) is well-established; however, the molecular mechanisms underlying this relationship remain poorly understood. This study aims to delineate shared genetic features PT RA uncover potential common pathways involved in their pathogenesis. Methods Gene expression data sets for were retrieved from Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) co-expressed gene modules identified...

10.1186/s40001-025-02376-y article EN cc-by European journal of medical research 2025-02-22
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