- Data Analysis with R
- COVID-19 Impact on Reproduction
- Biosimilars and Bioanalytical Methods
- COVID-19 epidemiological studies
- Chemistry and Stereochemistry Studies
- Demographic Trends and Gender Preferences
- COVID-19 and healthcare impacts
- Health disparities and outcomes
- Diverse Topics in Contemporary Research
- COVID-19 Pandemic Impacts
- Autopsy Techniques and Outcomes
- Maternal and Neonatal Healthcare
- Healthcare Systems and Challenges
- Diverse Approaches in Healthcare and Education Studies
- Computational and Text Analysis Methods
- Insurance, Mortality, Demography, Risk Management
- Morphological variations and asymmetry
- Data-Driven Disease Surveillance
- Diversity and Career in Medicine
- Bayesian Methods and Mixture Models
- Technology and Data Analysis
- Data Mining Algorithms and Applications
- Global Health Workforce Issues
- Medical Education and Admissions
- HIV/AIDS Research and Interventions
Stanford University
2016-2025
Advisory Board Company (United States)
2024
Gilead Sciences (United States)
2024
Yale University
2023
Stanford Medicine
2021-2023
Social Justice Ireland
2023
Met Office
2020-2022
Massachusetts General Hospital
2017-2021
Harvard University
2017-2021
Brigham and Women's Hospital
2020-2021
This cross-sectional study identifies surgical specialties with the greatest gender inequities among resident physicians and examines how long it will take for women in these to reach parity overall US population.
Abstract Background Mutations in the A bnormal Sp indle M icrocephaly related gene ( ASPM) are commonest cause of autosomal recessive primary microcephaly (MCPH) a disorder characterised by small brain and associated mental retardation. ASPM encodes mitotic spindle pole protein. It is suggested that MCPH phenotype arises from proliferation defects neural progenitor cells (NPC). Results We show microtubule minus end-associated protein recruited microtubule-dependent manner to pericentriolar...
This paper set out to identify the significant variables which affect residential low voltage (LV) network demand and develop next day total energy use (NDTEU) peak (NDPD) forecast models for each phase. The were developed using both autoregressive integrated moving average with exogenous (ARIMAX) neural (NN) techniques. data used this research was collected from a LV transformer serving 128 customers. It observed that temperature accounted half of demand. inclusion double exponential...
Abstract Background The purpose of this study was to complete a comprehensive analysis gender differences in faculty rank among U.S. emergency physicians that reflected all academic physicians. Methods We assembled list medicine ( EM ) with medical school appointments from Doximity.com linked detailed information on physician gender, age, years since residency completion, scientific authorship, National Institutes Health NIH research funding, and participation clinical trials. To estimate...
ABSTRACT Kaposi's sarcoma-associated herpesvirus (KSHV) infection is correlated with three human malignancies and can establish lifelong latent in multiple cell types within its host. In order to maintain infection, KSHV utilizes mechanisms evade the host immune response. One such mechanism expression of a family genes homology cellular interferon (IFN) regulatory factors (IRFs), known as viral IRFs (vIRFs). We demonstrate here that vIRF1, -2, -3 have differential ability block type I...
Kaposi's sarcoma-associated herpesvirus (KSHV) is a gammaherpesvirus known to establish lifelong latency in the human host. We and others have previously shown that three KSHV homologs of cellular interferon regulatory factors (IRFs), as viral IRFs (vIRFs), participate evasion host (IFN) response. report vIRF1 interacts with interferon-stimulated gene 15 (ISG15) E3 ligase, HERC5, context Toll-like receptor 3 (TLR3) activation IFN induction. The ISG15 protein covalently conjugated target...
To examine changes in U.S. medical school basic science faculty over the last 20 years (1998–2018), we undertook an observational study utilizing data from American Association of Medical Colleges Faculty Roster. Rank (Instructor, Assistant Professor, Associate and Professor), sex (Female), race/ethnicity (Asian, Black or African American, Hispanic, Latino, Spanish Origin, Multiple Race-Hispanic, White) were analyzed; this reflected a population 14,047 (1998) to 18,601 (2018) faculty....
<h3>Importance</h3> Given the mortality disparities among children and adolescents in rural vs urban areas, unique health care needs of pediatric patients, annual emergency department volume for this patient population, understanding availability physicians (EPs) is important. Information regarding available EP workforce limited, however. <h3>Objective</h3> To describe demographic characteristics, training, board certification, geographic distribution 2020 clinically active US. <h3>Design,...
Abstract Background Serological testing provides a record of prior infection with SARS-CoV-2, but assay performance requires independent assessment. Methods We evaluated 3 commercial (Roche Diagnostics pan-IG, and Epitope IgM IgG) 2 non-commercial (Simoa Ragon/MGH immunoassays against 1083 unique samples that included 251 PCR-positive 832 prepandemic samples. Results The Roche registered the highest specificity 99.6% (3/832 false positives), 99.5% (4/832), primary Simoa model 99.0% (8/832),...
In the United States, more chronic and preventive healthcare is being delivered in emergency department (ED) setting. Understanding availability of health services ED setting crucial. Our goal was to understand a subset US EDs explore how that has changed over time.
Objectives Accurate and reliable criteria to rapidly estimate the probability of infection with novel coronavirus-2 that causes severe acute respiratory syndrome (SARS-CoV-2) associated disease (COVID-19) remain an urgent unmet need, especially in emergency care. The objective was derive validate a clinical prediction score for SARS-CoV-2 uses simple widely available at point Methods Data came from registry data national REgistry suspected COVID-19 EmeRgency care (RECOVER network) comprising...
Objectives Estimating mortality risk in hospitalised SARS-CoV-2+ patients may help with choosing level of care and discussions patients. The Coronavirus Clinical Characterisation Consortium Mortality Score (4C Score) is a promising COVID-19 model. We examined the association factors 30-day hospitalised, full-code investigated discrimination calibration 4C Score. This was retrospective cohort study within RECOVER (REgistry suspected EmeRgency care) network. Setting 99 emergency departments...
To describe trends in emergency medicine faculty demographics, examining changes the proportion of historically underrepresented groups including female, Black, and Latinx over time.