A5100347812- Congenital heart defects research
- Nanocluster Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Photoreceptor and optogenetics research
- X-ray Diffraction in Crystallography
- Photochromic and Fluorescence Chemistry
- Mitochondrial Function and Pathology
- Peroxisome Proliferator-Activated Receptors
- Cardiovascular Conditions and Treatments
- Crystallization and Solubility Studies
- MicroRNA in disease regulation
- Freezing and Crystallization Processes
- Genetics and Neurodevelopmental Disorders
- Neurobiology and Insect Physiology Research
- Polydiacetylene-based materials and applications
- Crystallography and molecular interactions
- Nanoparticle-Based Drug Delivery
- Metabolism and Genetic Disorders
- Atrial Fibrillation Management and Outcomes
- High voltage insulation and dielectric phenomena
- Advanced Nanomaterials in Catalysis
- Biochemical Acid Research Studies
- Cardiac Arrhythmias and Treatments
- Tissue Engineering and Regenerative Medicine
Nanjing Medical University
2010-2020
Taizhou Second People's Hospital
2020
Second Affiliated Hospital of Nanjing Medical University
2020
Changzhou No.2 People's Hospital
2020
Jiangsu Province Hospital
2013-2016
Wuhan University
2011
Jiangxi Science and Technology Normal University
2011
Our previous study reported that microRNA-375 (miR-375) is significantly upregulated in ventricular septal myocardial tissues from 22‑week‑old fetuses with defect as compared normal controls. In the present study, specific effects of miR‑375 on P19 cell differentiation into cardiomyocyte‑like cells were investigated. Stable lines overexpressing or containing empty vector established, which could be efficiently induced presence dimethyl sulfoxide vitro. overexpression was verified using...
Fatty acid-binding protein 3 (FABP3) is a member of the intracellular lipid-binding family, and primarily expressed in cardiac muscle tissue. Previously, we found that FABP3 highly patients with ventricular-septal defects often used as plasma biomarker idiopathic dilated cardiomyopathy, may play significant role development these humans. In present study, aimed to investigate embryonic zebrafish heart, specifically how morpholino (MO) mediated knockdown would affect heart this species. Our...
Fatty acid binding protein 3 (FABP3, also termed heart‑type fatty protein) is a member of the intracellular lipid‑binding family that may be essential in transport, cell growth, cellular signaling and gene transcription. Previously, we demonstrated FABP3 was involved apoptosis‑associated congenital cardiac malformations; however, its mechanism regulation remains unclear. Apoptosis has increasingly been considered to important development. In present study, zebrafish model used investigate...
To explore the effects of LYRM1 knockdown on proliferation, apoptosis, differentiation and mitochondrial function in embryonic carcinoma (P19) cell model cardiac differentiation. Knockdown using small interfering RNA (siRNA) was confirmed by quantitative real-time PCR. Cell Counting Kit-8(CCK-8) proliferation assays cycle analysis demonstrated that gene silencing significantly inhibited P19 proliferation. Flow cytometry measurement their caspase-3 activities revealed increased apoptosis....
In this paper, we present a novel strategy to construct folic acid functionalized conjugated Cu nanoclusters (CuNCs) and silica (SiO2) nanocomposites for targeted detection of cancer cells. First all, BSA capped CuNCs were encapsulated into SiO2 matrix. The resulting CuNCs@SiO2 nanoparticles showed bright red fluorescence with an enhanced photoluminescence quantum yield compared free CuNCs, as well improved stability in complex biological environment owning the protection Upon attachment via...
Pillar insulators live-line clearing apparatus is to remove contaminations from the by insulating medium dry ice. It safe and efficient, without risk of flashover accidents. This paper describes experiments tests about controlling parameters which have impact on cleaning effect experiment platform. Available ice flow, rotating speed et al produced, fundamental further research pillar apparatus.
A new photochromic diarylethene compound, 1-[2-methyl-5-(3-chlorophenyl) -3-thienyl]-2-[2-methyl-5-(2-pyridine)-3-thienyl]perfluorocyclopentene(1a) was synthesized. its photochromism investigated. It exhibited good and functioned as an effective fluorescent photoswitch both in solution PMMA films.
A new photochromic diarylethene compound, 1-[2-methyl-3-benzothiophene]-2- [5-(3-chlorobenzene)-2-methyl-3-thienyl]perfluorocyclopentene(1a), was synthesized and its photochromism photo-induced anisotropy investigated. It showed good functioned as an effective fluorescent photoswitch in solution. In hexane, the open-ring isomer of 1a exhibited relatively strong fluorescence at 417 nm when excited 315 nm. PMMA film, also photochromism.
Objective To analyze the transmural lesions of different parts pig heart atrium received times ablation applied with Atricure bipolar radiofrequency system. Methods Six fresh (ex vivo time ＜ 20 min) hearts preserved intact were used as experimental objects and groups divided according to position. The system was in atrium, such posterior wall left anterior right close mitral ring.Ablate position lengthed about 2.0 cm same thickness an interval 0. 5 for 4 respectively, also recording every...