A5039361617- Reproductive Health and Technologies
- Ethics in medical practice
- Ethics and Legal Issues in Pediatric Healthcare
- Ethics in Clinical Research
- Assisted Reproductive Technology and Twin Pregnancy
- Demographic Trends and Gender Preferences
- Organ Donation and Transplantation
- Mental Health and Patient Involvement
- Maternal and Perinatal Health Interventions
- Healthcare Policy and Management
- Health Systems, Economic Evaluations, Quality of Life
- Global Maternal and Child Health
- Childhood Cancer Survivors' Quality of Life
- Health Policy Implementation Science
- Palliative Care and End-of-Life Issues
- Disaster Response and Management
- Healthcare cost, quality, practices
- Biomedical Ethics and Regulation
- Family Dynamics and Relationships
- Primary Care and Health Outcomes
- Health Services Management and Policy
- Patient Dignity and Privacy
- Child Welfare and Adoption
- Patient-Provider Communication in Healthcare
- Cystic Fibrosis Research Advances
University of Manchester
2000-2025
Centre for Social Innovation
2022
GlaxoSmithKline (United Kingdom)
2021-2022
University of Liverpool
2012-2021
Institute of Population, Health and Development
2019-2020
University of the Philippines Diliman
2018-2019
John Wiley & Sons (United States)
2018-2019
Hudson Institute
2019
Singer (United States)
2018-2019
Czech Academy of Sciences, Institute of Psychology
2018
1. Sandall J, Soltani H, Gates S, Shennan A, Devane D. Midwife led continuity models versus other of care for childbearing women. Cochrane Database Systematic Reviews 2013, Issue 8. Art. No.: CD004667. doi: 10.1002/14651858.cd004667.pub3 CrossRef Google Scholar
What is the recommended management for women and transgender men with regards to fertility preservation (FP), based on best available evidence in literature?The ESHRE Guideline Female Fertility Preservation makes 78 recommendations organization of care, information provision support, pre-FP assessment, FP interventions after treatment care. Ongoing developments are also discussed.The field has grown hugely last two decades, driven by increasing recognition importance potential loss as a...
Variations in intervention rates, without subsequent reductions adverse outcomes, can indicate overuse. We studied variations and associations between commonly used childbirth interventions adjusted for population characteristics.In this multinational cross-sectional study, existing data on 4,729,307 singleton births at ≥37 weeks 2013 from Finland, Sweden, Norway, Denmark, Iceland, Ireland, England, the Netherlands, Belgium, Germany (Hesse), Malta, United States, Chile were to describe...
Objective Alternatives to prospective informed consent enable children with life-threatening conditions be entered into trials of emergency treatments are needed. Across Europe, a process called deferred has been developed as an alternative. Little is known about the views and experiences those first-hand experience this controversial process. To inform how sought for future paediatric critical care trials, we explored parents practitioners involved in CATheter infections CHildren (CATCH)...
Artificial intelligence (AI) will have a significant impact on healthcare over the coming decade. At same time, health inequity remains one of biggest challenges. Primary care is both driver and mitigator inequities with AI gaining traction in primary care, there need for holistic understanding how affect inequities, through act providing potential system effects. This paper presents systematic scoping review ways implementation may inequity.Following approach, we searched literature related...
What information and support should be offered to donors, intended parents donor-conceived people, in general consideration of the availability direct-to-consumer genetic testing matching services?
Equivalence trials aim to show that two treatments have equivalent therapeutic effects. The approach is define, in advance, a range of equivalence -d +d for the treatment difference such any value clinically unimportant. If confidence interval difference, calculated after trial, lies entirely within interval, then claimed. Glaxo Wellcome has carried out series using this methodology assess new formulations inhaled beta-agonists and steroids asthma. Eleven these are used review some practical...
ABSTRACT Like any discipline, bioethics is a developing field of academic inquiry; and recent trends in scholarship have been towards more engagement with empirical research. This ‘empirical turn’ has provoked extensive debate over how such ‘descriptive’ research carried out the social sciences contributes to distinctively normative aspect bioethics. paper will address this issue by practical methodology for inclusion data from science studies into ethical deliberation. be based on...
This paper reports the process and outcome of a consensus finding project, which began with meeting at Brocher Foundation in May 2015. The project sought to generate reach on standards practice for Empirical Bioethics research. involved 16 academics from 5 different European Countries, range disciplinary backgrounds.The used modified Delphi approach.Consensus was reached 15 practice, organised into 6 domains research (Aims, Questions, Integration, Conduct Work, Normative Work; Training &...
Donor conception has been practised for many years, initially as a means of bypassing male fertility problems through the use donated semen. More recently, semen donation provided by which single woman and women in same sex relationships may build family without engaging penetrative heterosexual intercourse, while embryo egg have new family-building opportunities other groups, such post-menopausal women. A key topic debate, policy formulation, regulation extent to donor-conceived people...
To inform the design of a randomised controlled trial (called EcLiPSE) to improve treatment children with convulsive status epilepticus (CSE). EcLiPSE requires use controversial deferred consent process.Qualitative interview and focus group study.8 UK support groups for parents who have chronic or acute health conditions experience paediatric emergency care.17 parents, whom 11 participated in telephone interviews (10 mothers, 1 father) 6 (5 father). (35%) were bereaved 7 (41%) had...
In 2008 UK legislation was amended to enable the use of deferred consent for paediatric emergency care (EC) trials in recognition practical and ethical difficulties obtaining prospective an situation. However, ambiguity about how make acceptable parents, children practitioners remains. particular, little is known practitioners' views experiences seeking this setting. As part a wider study investigating methods (called CONNECT), 20 item online questionnaire sent by email inviting (doctors...
This article considers the disclosure, sharing and exchange of information on being donor conceived within families, drawing data from a study undertaken with donor-conceived adults registered UK Donor Link (a voluntary DNA-linking register). paper narratives how respondents found out they were what events triggered disclosure this information. then goes to examine role secrecy played in their family life uses concept 'display' explore affected relationships immediate extended family....
The literature on patient public involvement and engagement (PPIE) in health research has grown significantly the last decade, with a diverse range of definitions topologies promulgated. This led to disputes over what central functions purpose PPIE is, this turn makes it difficult assess evaluate practice. paper argues that most important function is attempt make more democratic. Bringing fore locating wider context changes contemporary forms democratic provides greater conceptual clarity...
What effect does direct-to-consumer genetic testing (DTCGT) have on information finding and sharing in relation to gamete donor conception?
What are the experiences of donor-conceived adults and donors who searching for a genetic link through use DNA-based voluntary register service?Donor-conceived held positive beliefs about their search although some concerns in relation to finding genetically linked relative were reported, these not barrier searching.Research with people has consistently identified interest learning about-and cases making contact with-their donor other relatives. However, individuals or rarely have...
Abstract Recently the World Health Organization ( WHO ) has highlighted need to strengthen mental health systems following emergencies, including natural and manmade disasters. Mental services be informed by culturally attuned evidence that is developed through research. Therefore, there an urgent establish rigorous ethical research practice underpin evidence‐base for delivered during emergencies.
Emergency research with critically unwell children is vital to make sure that the most ill and injured benefit from evidence-based healthcare.1 Ethical guidance require consent be sought parents (or legal representatives) on behalf of their children2 before initiated, yet concerns about problems in seeking parents’ when child have been a significant barrier conducting clinical trials.3 ,4 Taking time out seek informed starting treatment will often difficult justify as delaying any...
In 2005, UK legislation was changed requiring any donor of gametes or embryos used in the treatment others to agree disclosure their identity offspring reaching age 18.This paper analyses responses a survey existing donors' views on removal anonymity that undertaken by Department Health (UK) as part its review preceded changes law anonymity. The provides an insight into what it is about loss some donors find problematic, indicating although will be reluctant donate under conditions...