- Reproductive Biology and Fertility
- Ovarian function and disorders
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Cancer Risks and Factors
- Renal and related cancers
- Endometriosis Research and Treatment
- Sperm and Testicular Function
- Prenatal Screening and Diagnostics
- Ovarian cancer diagnosis and treatment
- Childhood Cancer Survivors' Quality of Life
- Long-Term Effects of COVID-19
- Reproductive System and Pregnancy
- Pluripotent Stem Cells Research
- LGBTQ Health, Identity, and Policy
- Estrogen and related hormone effects
- BRCA gene mutations in cancer
- Respiratory Support and Mechanisms
- Diabetic Foot Ulcer Assessment and Management
- Birth, Development, and Health
- Endometrial and Cervical Cancer Treatments
- Menopause: Health Impacts and Treatments
- COVID-19 Clinical Research Studies
- Family Support in Illness
- Pregnancy and preeclampsia studies
Karolinska Institutet
2016-2025
Karolinska University Hospital
2016-2025
Uppsala University
2012-2020
Wunschbaby Institut für Kinderwunsch
2020
Medical University of Vienna
2020
Ankara University
2018
Universidade de São Paulo
2018
Inserm
2013
New York Medical College
2010-2013
Agence de la Biomédecine
2013
Transgender healthcare is a rapidly evolving interdisciplinary field. In the last decade, there has been an unprecedented increase in number and visibility of transgender gender diverse (TGD) people seeking support gender-affirming medical treatment parallel with significant rise scientific literature this area. The World Professional Association for Health (WPATH) international, multidisciplinary, professional association whose mission to promote evidence-based care, education, research,...
What is the recommended management for women and transgender men with regards to fertility preservation (FP), based on best available evidence in literature?The ESHRE Guideline Female Fertility Preservation makes 78 recommendations organization of care, information provision support, pre-FP assessment, FP interventions after treatment care. Ongoing developments are also discussed.The field has grown hugely last two decades, driven by increasing recognition importance potential loss as a...
How do transgender men experience fertility preservation (FP) by cryopreservation of oocytes? The procedures required prior to oocyte cryopreservation, such as hormonal ovarian stimulation and transvaginal ultrasound (TVS), have a negative impact on gender dysphoria they are closely linked the men's female assigned sex at birth, which is incompatible with their current status. Transgender persons often high dissatisfaction sex-specific body features, genital organs...
Abstract STUDY QUESTION Which clinical and embryological factors should be considered to apply double embryo transfer (DET) instead of elective single (eSET)? SUMMARY ANSWER No or factor per se justifies a recommendation DET eSET in IVF/ICSI. WHAT IS KNOWN ALREADY is correlated with higher rate multiple pregnancy, leading subsequent increase complications for both mother babies. These include preterm birth, low birthweight, other perinatal adverse outcomes. To mitigate the risks associated...
Purpose The aim was to investigate male and female cancer survivors' perception of fertility-related information use fertility preservation (FP) in connection with treatment during reproductive age. Methods study sample consisted survivors diagnosed from 2003 2007 identified population-based registers Sweden. Inclusion criteria included who were age 18 45 years at diagnosis had lymphoma, acute leukemia, testicular cancer, ovarian or breast treated chemotherapy. Of 810 eligible participants,...
The aim was to investigate desire for children, difficulties achieving a pregnancy, and infertility distress among survivors 3 7 years after cancer treatment in reproductive age. Cancer were identified national population-based registries. Eligible subjects presented with selected diagnoses between 2003 2007 the ages of 18 45. A postal questionnaire including study-specific questions, Short-Form 36 Health Survey Fertility Problem Inventory, sent 810 survivors, 484 participated (60 %...
The aim of this study is to report the current status ovarian tissue cryopreservation among alternatives for fertility preservation in Nordic countries.A questionnaire was sent 14 academic reproductive centers with established programs. It covered cases performed up December 2014, standard procedures and oocyte outcomes following transplantation.Among countries, Denmark Norway practice as a clinical treatment (822 164 cases, respectively) their programs are centralized. In Sweden (457...
Novel pathways to parenthood [oocyte cryopreservation, allowance of surrogacy, uterus transplantation, and assisted reproductive treatments (ART) for single women] are currently being discussed. This study investigates women's attitudes towards oocyte cryopreservation ART procedures that not allowed or still under investigation in Sweden, whether the differ between urban women from a national cohort.Two thousand randomly selected Swedish females aged 30-39 years, 1000 residents Stockholm...
In Scandinavian countries, programs for fertility preservation are offered free of charge at tertiary-care university hospitals to all patients facing treatments with risk subsequent sterility. this prospective study we aimed investigate trends in female patients' choices after counseling and outcomes during follow up relation benign vs malignant indications.Data on 1254 females including 1076 adults 178 girls who received either oncologic (n = 852) or indications 402) Karolinska University...
Importance Young women with breast cancer who have germline pathogenic variants in BRCA1 or BRCA2 face unique challenges regarding fertility. Previous studies demonstrating the feasibility and safety of pregnancy survivors included limited data BRCA carriers. Objective To investigate cumulative incidence disease-free survival young are Design, Setting, Participants International, multicenter, hospital-based, retrospective cohort study conducted at 78 participating centers worldwide. The...
The treatment landscape of solid tumors has changed markedly in the last years. Molecularly targeted treatments and immunotherapies have been implemented have, many cancers, lowered risk relapse prolonged survival. Patients with harboring specific targetable molecular alterations or mutations are often a younger age, hence future fertility family building can be important concerns this group. However, there great uncertainties regarding effect new drugs on reproductive functions, including...
Background. Being diagnosed with cancer constitutes not only an immediate threat to health, but treatments may also have a negative impact on fertility. Retrospective studies show that many survivors regret having received fertility-related information and being offered fertility preservation at time of diagnosis. This qualitative study investigates newly patients' experiences communication how they reason about the risk future infertility.Material methods. Informants were recruited three...