A5052061502- Advanced Sensor and Energy Harvesting Materials
- Tactile and Sensory Interactions
- Thermoregulation and physiological responses
- Organ Transplantation Techniques and Outcomes
- Plant tissue culture and regeneration
- Non-Invasive Vital Sign Monitoring
- Liver Disease and Transplantation
- Neuroscience and Neural Engineering
- Biosensors and Analytical Detection
- Plant Molecular Biology Research
- Plant Gene Expression Analysis
- Advanced Chemical Sensor Technologies
- Cardiac Arrhythmias and Treatments
- Plant Stress Responses and Tolerance
- Turfgrass Adaptation and Management
- Mechanical Circulatory Support Devices
- Advanced Fluorescence Microscopy Techniques
- Nanoplatforms for cancer theranostics
- Analytical Chemistry and Sensors
- Transplantation: Methods and Outcomes
- Dielectric materials and actuators
- Integrated Circuits and Semiconductor Failure Analysis
- Asphalt Pavement Performance Evaluation
- Advanced biosensing and bioanalysis techniques
- Transgenic Plants and Applications
Northwestern University
2019-2025
InterSystems (United States)
2023-2025
DEVCOM Army Research Laboratory
2020
INTEGRIS Baptist Medical Center
2020
Los Alamos National Laboratory
2018
United States Army Research Office
2015-2017
Ministry of Transportation of Ontario
2014-2016
MC10 (United States)
2011-2015
Mitsubishi Corporation (Japan)
2015
Stony Brook University
2014
Battery-free, wireless microfluidic/electronic system for multiparameter sweat analysis.
Curved surfaces, complex geometries, and time-dynamic deformations of the heart create challenges in establishing intimate, nonconstraining interfaces between cardiac structures medical devices or surgical tools, particularly over large areas. We constructed area designs for diagnostic therapeutic stretchable sensor actuator webs that conformally wrap epicardium, robust contact without sutures, mechanical fixtures, tapes, adhesives. These multifunctional web exploit open, mesh layouts mount...
Contemporary cardiac and heart rate monitoring devices capture physiological signals using optical electrode-based sensors. However, these generally lack the form factor mechanical flexibility necessary for use in ambulatory home environments. Here, we report an ultrathin (~1 mm average thickness) highly flexible wearable sensor (WiSP) designed to be minimal cost (disposable), light weight (1.2 g), water resistant, capable of wireless energy harvesting. Theoretical analyses system-level...
Wearable microfluidic system enables remote analysis of sweat rate and chloride loss for assessing personalized fluid needs.
Abstract Wearable monitoring systems provide valuable insights about the state of wellness, performance, and progression diseases. Although conventional wearable have been effective in measuring a few key biophysical markers, they offer limited into biochemical activity are otherwise cumbersome ambulatory modes use, relying on wired connections, mechanical straps, bulky electronics. Recent advances skin‐interfaced microfluidics, stretchable/flexible electronics, mechanics created new with...
Soft microfluidic systems that capture, store, and perform biomarker analysis of microliter volumes sweat, in situ, as it emerges from the surface skin, represent an emerging class wearable technology with powerful capabilities complement those traditional biophysical sensing devices. Recent work establishes applications real-time characterization sweat dynamics chemistry context sports performance healthcare diagnostics. This paper presents a collection advances biochemical sensors designs...
The concentration of chloride in sweat remains the most robust biomarker for confirmatory diagnosis cystic fibrosis (CF), a common life-shortening genetic disorder. Early via quantitative assessment allows prompt initiation care and is critically important to extend life expectancy improve quality life. collection analysis using conventional wrist-strapped devices iontophoresis can be cumbersome, particularly infants with fragile skin, who often have insufficient production. Here, we...
Soft microfluidics with reference reactions enable quantitative sweat ammonia–ethanol assay.
The possibility of primary sclerosing cholangitis (PSC) recurrence after liver transplantation has been debated. aim this study is to examine whether recurrent PSC and chronic rejection (CR) are different expressions the same disease process.One hundred consecutive patients receiving 118 grafts for diagnosis were reviewed placed into three groups: group A, disease, as evidenced by cholangiographic pathologic findings with radiographic arterial flow (n=18; 15.7%); B, those who developed CR...
Comprehensive analysis of sweat chemistry provides noninvasive health monitoring capabilities that complement established biophysical measurements such as heart rate, blood oxygenation, and body temperature. Recent developments in skin-integrated soft microfluidic systems address many challenges associated with standard technologies collection analysis. However, recording time-dependent variations composition requires bulky electronic power sources, thereby constraining form factor, cost,...
The U.S. is a long-time international leader in HPC, rooted strong and innovative computing industry that complemented by partnerships with among federal agencies, academia, industries whose success relies on HPC. advent of exascale brings challenges traditional simulation as well areas colloquially referred to “Big Data.” Within this context, we describe the strategy: 1) National Strategic Computing Initiative, multiple agency effort comprehensively addressing computational science...
Eccrine sweat contains a rich blend of electrolytes, metabolites, proteins, metal ions, and other biomarkers. Changes in the concentrations these chemical species can indicate alterations hydration status they also reflect health conditions such as cystic fibrosis, schizophrenia, depression. Recent advances soft, skin-interfaced microfluidic systems enable real-time measurement local loss biomarker concentrations, with wide range applications healthcare. Uses certain contexts involve,...
Abstract Dehydration has many deleterious effects on cognitive and physical performance as well physiological function, in the context of sports, industrial work, clinical rehabilitation, military applications. Because sweat loss electrolyte vary across individuals, conventional testing strategies using absorbent patch techniques are employed laboratory settings to characterize biomarkers; however, these not suitable for remote environments. Here, an updated wearable microfluidic system...
The phenylpropanoid enzyme 4‐coumarate:coenzyme A ligase (4CL) plays a key role in linking general metabolism to end‐product specific biosynthetic pathways. During vascular system and floral organ differentiation, the parsley 4CL‐1 gene is expressed restricted set of tissues cell types where 4CL activity required supply precursors for synthesis diverse phenylpropanoid‐derived products such as lignin flavonoids. In order localize cis ‐acting elements which specify complex patterns expression,...
Established classes of high-performance electronics have driven advances in interventional biomedicine. However, the large size, planar geometry and stiff mechanical properties standard conventional employed medical devices give rise to important integration challenges with soft biological tissue. Stretchable flexible biointegrated could improve treatment procedures across a broad range applications, including cardiac, neural endovascular therapies. Here we present novel mechanics, materials...