A5057799979- Blood Coagulation and Thrombosis Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Cardiovascular Issues in Pregnancy
- Acute Myocardial Infarction Research
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- Prenatal Screening and Diagnostics
- Global Maternal and Child Health
- Neonatal and fetal brain pathology
- Pelvic floor disorders treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Gestational Diabetes Research and Management
- Systemic Lupus Erythematosus Research
- Fetal and Pediatric Neurological Disorders
- Neonatal and Maternal Infections
- Anesthesia and Pain Management
- Clinical practice guidelines implementation
- Cardiac, Anesthesia and Surgical Outcomes
- Hernia repair and management
- Breastfeeding Practices and Influences
- Assisted Reproductive Technology and Twin Pregnancy
- Streptococcal Infections and Treatments
- Platelet Disorders and Treatments
Oslo University Hospital
2015-2025
University of Oslo
2016-2025
Radboud University Nijmegen
2022-2023
Radboud University Medical Center
2022-2023
Amsterdam University Medical Centers
2023
University of Amsterdam
2023
Aalborg University Hospital
2023
Royal College of Physicians and Surgeons of Canada
2023
Aarhus University Hospital
2023
Centre Hospitalier Universitaire de Saint-Étienne
2023
In high-income countries, the incidence of severe postpartum hemorrhage (PPH) has increased. This important public health relevance because PPH is a leading cause major maternal morbidity. However, few studies have identified risk factors for within contemporary obstetric cohort.We performed case-control study to identify among cohort women who delivered at one three hospitals in Norway between 2008 and 2011. A case (severe PPH) was classified by an estimated blood loss ≥1500 mL or need...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAmine specificity in transpeptidation. Inhibition of fibrin cross-linkingLaszlo. Lorand, Norman G. Rule, Helen H. Ong, R. Furlanetto, Anne. Jacobsen, J. Downey, Nevzat. Oner, and Joyce. Bruner-LorandCite this: Biochemistry 1968, 7, 3, 1214–1223Publication Date (Print):March 1, 1968Publication History Published online1 May 2002Published inissue 1 March...
Objective To assess the effect of Pregnant+ app on 2-hour glucose level routine postpartum oral tolerance test (OGTT) among women with gestational diabetes mellitus (GDM). The was designed to provide information about GDM, and promote physical activity a healthy diet. Design A multicentre, non-blinded randomised controlled trial. Setting Five outpatient clinics in Oslo region. Participants Women ≥18 years old OGTT blood ≥9 mmol/L who owned smartphone; understood Norwegian, Urdu or Somali;...
Background Group B Streptococcus (GBS) is a major cause of serious neonatal infection but its role in maternal morbidity has received little investigation. The aim this study was to determine whether GBS colonization at delivery associated with increased risk peripartum infection. Methods In prospective cohort study, 1746 unselected women had vaginal-rectal culture taken the onset labor. Diagnosis based on combination two or more signs symptoms including fever, breast pain, severe wound...
Objective To evaluate the effect and dose of dalteparin given to pregnant women with acute venous thromboembolism. Design An observational study in Norway. Setting Delivery haematological departments Population Twenty women, aged 22–41 years, thromboembolism verified by objective means. Methods Patients were treated from diagnosis until delivery. Treatment was monitored anti‐activated factor Xa (anti‐Xa) activity, adjusted achieve target 0.5–1.0 U/mL 2–3 hours post‐injection. Main outcome...
Abstract Objective To investigate risk factors for stillbirths by cause, using the Causes of Death and Associated Conditions ( CODAC ) classification system perinatal deaths. Design Case‐control study. Setting Two university hospitals in Oslo, Norway, January 1990 through December 2003. Sample Women with stillbirth after 22 gestational weeks (n = 377) controls live births 1 215), a subsample 105 cases 262 controls. Methods Socio‐demographic, clinical thrombophilic were assessed cause death...
The procoagulant state in cancer increases the thrombotic risk, but also supports tumor progression. To investigate molecular mechanisms controlling and hemostasis, we conducted a case-control study of genotypic phenotypic variables tissue factor (TF) pathway coagulation breast cancer. 366 patients 307 controls were genotyped for SNPs (n = 41) F2, F3 (TF), F5, F7, F10, TFPI EPCR genes, assayed plasma markers (thrombin generation, activated protein C (APC) resistance, D-dimer, antithrombin,...
The promotion of a healthy diet, physical activity and measurement blood glucose levels are essential components in the care for women with gestational diabetes mellitus (GDM). Smartphones offer new way to promote health behaviour. main aim is investigate if use Pregnant+ app, addition standard care, results better compared current only, GDM.
Abstract Introduction In response to the increasing rates of induction labor (IOL), outpatient IOL has emerged as a potential approach enhance women's satisfaction while reducing costs and staffing requirements. There is growing interest in oral misoprostol an method, particularly Nordic region. This study aims evaluate clinical outcomes feasibility implementing with procedure. Material Methods multicenter, prospective cohort part Labor Induction Inpatient Outpatient (LINO) project (...
Introduction Presently, more than one in four births high-income countries undergo labour induction. Induction of is an independent risk factor for adverse obstetric outcomes, including high rates operative delivery. Two drugs, hyoscine butylbromide and sodium bicarbonate, have been used to facilitate cervical dilation prevent uterine lactate accumulation. However, no previous randomised trial has systematically studied the separate combined effects these drugs women with induction labour....
Abstract Introduction A recent study recommended 5.2 mmol/L as a cutoff for fetal blood sample (FBS) lactate in labor the StatStrip Lactate®/Lactate Xpress® meter. In present study, we validated FBS cutoffs larger population‐based setting, with different CTG guidelines, testing external validity. Material and Methods We conducted prospective at Oslo University Hospital, Ullevål, Norway, tertiary referral obstetric department 7000 annual deliveries. Women singleton fetus cephalic presentation...
Objectives To evaluate the long-term consequences of pregnancy-related venous thrombosis (VT) by assessment generic quality-of-life (QOL), well-being, general health and daily-life functioning. We also wanted to impact frequently occurring complication post-thrombotic syndrome (PTS) after that deep vein (DVT). Design Population-based cross-sectional, case–control study. Setting 18 Norwegian hospitals during 1990–2003. Participants The study population comprised 559 cases with a validated...