- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Reproductive tract infections research
- Pregnancy and preeclampsia studies
- Pregnancy-related medical research
- Preterm Birth and Chorioamnionitis
- Ectopic Pregnancy Diagnosis and Management
- Pelvic floor disorders treatments
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Bacterial Identification and Susceptibility Testing
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Prenatal Screening and Diagnostics
- Urinary Tract Infections Management
- Fetal and Pediatric Neurological Disorders
- Genomics and Phylogenetic Studies
- Reproductive Health and Contraception
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Blood Coagulation and Thrombosis Mechanisms
- Endometriosis Research and Treatment
- Cleft Lip and Palate Research
- Cardiovascular Issues in Pregnancy
- Neonatal and fetal brain pathology
Assistance Publique Hôpitaux de Marseille
2016-2025
Hôpital de la Conception
2016-2025
Institut de Recherche pour le Développement
2016-2025
Inserm
2013-2025
Aix-Marseille Université
2016-2025
Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
2014-2025
Centre National de la Recherche Scientifique
2011-2025
Hôpital Nord
2015-2024
Méditerranée Infection Foundation
2016-2024
Lyon Genou Centre Albert Trillat
2009-2024
To estimate maternal outcome after conservative management of placenta accreta.This retrospective multicenter study sought to include all women treated conservatively for accreta in tertiary university hospital centers France from 1993 2007. Conservative was defined by the obstetrician's decision leave situ, partially or totally, with no attempt remove it forcibly. The primary success treatment, uterine preservation. secondary a composite measure severe morbidity including sepsis, septic...
Bacterial vaginosis (BV) is a poorly detected public health problem that associated with preterm delivery and for which no reliable diagnostic tool exists.Molecular analysis of 231 vaginal samples, classified by Gram stain-based Nugent score, was used to propose molecular criteria BV; these were prospectively applied 56 new samples. A quantitative targeting 8 BV-related microorganisms human gene developed using specific real-time polymerase chain reaction assay serial dilutions plasmid...
Prophylactic administration of tranexamic acid has been associated with reduced postpartum blood loss after cesarean delivery in several small trials, but evidence its benefit this clinical context remains inconclusive.
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The role of lung ultrasound has never been evaluated in parturients with severe preeclampsia. authors' first aim was to assess the ability detect pulmonary edema second highlight relation between B-lines and increased left ventricular end-diastolic pressures.This prospective cohort study conducted a level-3 maternity during 12-month period. Twenty preeclampsia were consecutively enrolled. Both cardiac examinations performed before (n = 20) after delivery 20). Each parturient compared control...
Background. Bacterial vaginosis is a risk factor for preterm birth. The various conventional methods its diagnosis are laborious and not easily reproducible. Molecular quantification have been reported recently, but the specific factors they might identify remain unclear. Methods. A prospective multicenter national study included pregnant women at of quantitative molecular tool using real-time polymerase chain reaction assay serial dilutions plasmid suspension quantified Atopobium vaginae,...
In the present study, we explored microparticles involved in control of hemostatic equilibrium, i.e originating from platelet, endothelial cells and total MP defined as annexin V positive microparticles. Our aim was to analyze level procoagulant activity these normal pregnancy pregnancies complicated with preeclampsia or isolated intrauterine growth restriction. We reported increased levels platelet compared non pregnant healthy women. Number significantly together their activity....
Q fever is a zoonosis caused by Coxiella burnetii. During pregnancy, it may result in obstetric complications, such as spontaneous abortion, intrauterine growth retardation, fetal death, and premature delivery. Pregnant women are exposed to the risk of chronic fever.We included 53 pregnant who received diagnosis fever. We compared incidence maternal complications for long-term cotrimoxazole treatment (n=16) with that did not receive (n=37); was defined oral administration...
Objective. The purpose of this prospective study was to evaluate urinary and sexual function after the tension‐free vaginal tape (TVT) support procedure for stress incontinence (SUI). Methods. Between January 1999 July 2002 a total 71 patients underwent comprehensive examination including urodynamics mailed self‐administered questionnaire assessment voiding before treatment SUI by TVT. Results. Based on objective findings TVT considered as curative in 48 (87.3%). Comparison preoperative...
To estimate the relationship between vaginal quantification of main microorganisms related with bacterial vaginosis and risk preterm delivery among women labor.Molecular methods were used to prospectively quantify Lactobacillus species, Gardnerella vaginalis, Atopobium vaginae, Mycoplasma hominis in fluid samples from admitted for spontaneous labor intact membranes July 2007 through 2008. The primary outcome measure was concentration at admission delivery, before 37 weeks gestation....
<h3>Importance</h3> Randomized trials have not focused on neonatal complications of glyburide for women with gestational diabetes. <h3>Objective</h3> To compare oral vs subcutaneous insulin in prevention perinatal newborns <h3>Design, Settings, and Participants</h3> The Insulin Daonil trial (INDAO), a multicenter noninferiority randomized conducted between May 2012 November 2016 (end participant follow-up) 13 tertiary care university hospitals France including 914 singleton pregnancies...
To evaluate whether daily enoxaparin, added to low-dose aspirin, started before 14 weeks of gestation reduces placenta-mediated complications in pregnant women with previous severe preeclampsia diagnosed 34 gestation.In this open-label multicenter randomized trial, we enrolled consenting gestation, gestational age at randomization 7-13 weeks, singleton pregnancy, and no plan for anticoagulation. Eligible patients were randomly assigned a one-to-one ratio receive either 4,000 international...