Élie Azria
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Global Maternal and Child Health
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy-related medical research
- Pregnancy and preeclampsia studies
- Healthcare Systems and Practices
- Migration, Health and Trauma
- Neonatal Respiratory Health Research
- Health, Medicine and Society
- Prenatal Screening and Diagnostics
- Preterm Birth and Chorioamnionitis
- HIV/AIDS Research and Interventions
- Maternal Mental Health During Pregnancy and Postpartum
- Gestational Diabetes Research and Management
- Ectopic Pregnancy Diagnosis and Management
- Birth, Development, and Health
- Cardiovascular Issues in Pregnancy
- Infant Development and Preterm Care
- Blood transfusion and management
- Migration, Identity, and Health
- Pelvic floor disorders treatments
- Endometriosis Research and Treatment
- HIV-related health complications and treatments
- Breastfeeding Practices and Influences
Hôpital Paris Saint-Joseph
2015-2024
Inserm
2015-2024
Université Paris Cité
2015-2024
Centre de Recherche Épidémiologie et Statistique
2015-2024
Sorbonne Paris Cité
2015-2024
Gouvernance, Risque, Environnement, Développement
2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2021-2024
Fédération Hospitalo-Universitaire, Paris Center for Microbiome Medicine
2024
Université de Bordeaux
2020-2023
Saint Joseph Hospital
2018-2023
Abstract Background. The efficacy of preventing perinatal transmission (PT) human immunodeficiency virus type 1 (HIV-1) depends on both viral load (VL) and treatment duration. objective this study was to determine whether initiating highly active antiretroviral therapy (ART) before conception has the potential eliminate PT. Methods. A total 8075 HIV-infected mother/infant pairs included from 2000 2011 in national prospective multicenter French Perinatal Cohort (ANRS-EPF) received ART,...
The use of tranexamic acid reduces mortality due to postpartum hemorrhage. We investigated whether the prophylactic administration in addition oxytocin women with vaginal delivery would decrease incidence In a multicenter, double-blind, randomized, controlled trial, we randomly assigned labor who had planned singleton live fetus at 35 or more weeks gestation receive 1 g placebo, administered intravenously, after delivery. primary outcome was hemorrhage, defined as blood loss least 500 ml,...
Prophylactic administration of tranexamic acid has been associated with reduced postpartum blood loss after cesarean delivery in several small trials, but evidence its benefit this clinical context remains inconclusive.
Intrapartum intravenous zidovudine (ZDV) prophylaxis is a long-standing component of prevention mother-to-child transmission (MTCT) human immunodeficiency virus (HIV) in high-resource countries. In some recent guidelines, ZDV no longer systematically recommended for mothers receiving combination antiretroviral therapy (cART) with low viral load. We evaluated the impact according to load and obstetrical conditions. All HIV-1-infected women delivering between 1 January 1997 31 December 2010...
Umbilical cord blood from healthy neonates with no known infectious exposure contains T cells an effector memory–like phenotype.
OBJECTIVE: To evaluate the association between planned mode of delivery and neonatal mortality morbidity in an unselected population women with twin pregnancies. METHODS: The JUmeaux MODe d'Accouchement (JUMODA) study was a national prospective population-based cohort study. All pregnancies their neonates born at or after 32 weeks gestation cephalic first were recruited 176 maternity units France from February 2014 to March 2015. primary outcome composite intrapartum morbidity. Comparisons...
To assess neonatal morbidity in twin pregnancy according to the planned mode of delivery.A retrospective cohort study 758 consecutive sets twins born after 35 weeks gestation with a cephalic-presenting first was undertaken level III maternity unit which active management second delivery is performed routinely. The primary outcome composite measure mortality and morbidity, including pH less than 7.0, 5-minute Apgar score 4, intensive care transfer more 4 days, pneumothorax, fracture. Control...
The first reports on the pandemic influenza 2009 A/H1N1v from USA, Mexico, and Australia indicated that this disease was associated with a high mortality in pregnant women. aim of study to describe compare characteristics severe critically ill non-severe women A/H1N1v-related illness France.A national registry created screen laboratory-confirmed influenza. Three hundred fifteen patients 46 French hospitals were included: 40 admitted intensive care units (severe outcomes), 111 hospitalized...
To assess whether outpatient cervical ripening at 41 0/7 weeks of gestation with the nitric oxide donor isosorbide mononitrate reduces cesarean delivery rates in nulliparous women an unfavorable cervix.We recruited pregnant a Bishop score less than 6 randomized, multicenter, double-blind, placebo-controlled trial. Women received 40 mg vaginal or placebo 0/7, 2/7, and 4/7 gestation. They returned home between visits. At 5/7 gestation, for who had not yet given birth, labor was induced...
Background. Morbidity and mortality are higher among human immunodeficiency virus (HIV) exposed but uninfected (HEU) infants than unexposed infants, particularly if the mother had a low CD4 count. We investigated possible association between maternal immune depression during pregnancy risk of infection in HEU national French Perinatal Cohort (EPF). Methods. All neonates, born alive, to HIV-1–infected women enrolled EPF 2002 2010 were included. The primary outcome was first serious...
Objective Because the effectiveness of antenatal care in reducing pregnancy complications is still discussed despite widespread recommendations its use, we sought to assess association between utilisation recommended and severe maternal ( SMM ) perinatal morbidity SPM ). Design Prospective cohort study. Setting Four maternity units around Paris 2010–2012. Sample 9117 women with singleton pregnancies. Methods Logistic regression models adjusted for social, demographic medical characteristics....
Maternal social deprivation is associated with an increased risk of adverse maternal and perinatal outcomes. Inadequate prenatal care utilization (PCU) likely to be important intermediate factor. The health system in France provides essential services all pregnant women irrespective their socioeconomic status. Our aim was assess the association between PCU. analysis performed database multicenter prospective PreCARE cohort study. population source consisted parturient registered for delivery...
In infants, the mode of acquisition CC17 group B Streptococcus (GBS), hypervirulent clone responsible for late-onset disease (LOD), remains elusive.In a prospective multicenter study in France, we evaluated GBS colonization mother-baby pairs with 2 months follow-up between 2012 and 2015. Criteria included positivity at antenatal screening or delivery. Maternal vaginal samples infant oral cavity stool were analyzed delivery, 21 ± 7 days (D21), 60 (D60) post-delivery.A total 890 analyzed....
Abstract This study aimed to identify the risk factors for placenta accreta spectrum (PAS) in women who had at least one previous cesarean delivery and a previa or low-lying. The PACCRETA prospective population-based took place 12 regional perinatal networks from 2013 through 2015. All with more prior cesareans low lying were included. Placenta was diagnosed according standardized clinical histological criteria. Of 520,114 deliveries, 396 fulfilled inclusion criteria; 108 classified PAS...