S. Jaffuel

ORCID: 0000-0003-1449-717X
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About
Contact & Profiles
Research Areas
  • Pneumonia and Respiratory Infections
  • HIV Research and Treatment
  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • Bacterial Infections and Vaccines
  • Respiratory viral infections research
  • Infective Endocarditis Diagnosis and Management
  • Bacterial biofilms and quorum sensing
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Hepatitis C virus research
  • Fungal Infections and Studies
  • Nail Diseases and Treatments
  • Tuberculosis Research and Epidemiology
  • Infectious Diseases and Tuberculosis
  • Pharmaceutical Practices and Patient Outcomes
  • Antibiotic Use and Resistance
  • Orthopedic Infections and Treatments
  • Plant Pathogenic Bacteria Studies
  • SARS-CoV-2 and COVID-19 Research
  • Dermatological diseases and infestations
  • Cystic Fibrosis Research Advances
  • Syphilis Diagnosis and Treatment
  • Parvovirus B19 Infection Studies
  • Legionella and Acanthamoeba research
  • Influenza Virus Research Studies

Centre Hospitalier Régional Universitaire de Brest
2008-2025

Inserm
2015-2024

Assistance Publique – Hôpitaux de Paris
2015-2024

Hôpitaux Universitaires Paris-Ouest
2024

Université Paris-Saclay
2024

Centre de recherche en Epidémiologie et Santé des Populations
2024

Hôpital de l'Antiquaille
2024

Hôpital Maison Blanche
2005-2024

Hospital for Tropical Diseases
2024

Institut Pascal
2023

Nelly Briand Josiane Warszawski Laurent Mandelbrot Catherine Dollfus E. Pannier and 95 more L. Cravello Rose Nguyen Sophie Matheron Norbert Winer Roland Tubiana Christine Rouzioux Albert Faye Stéphane Blanche Laurent Mandelbrot Françoise Meier Dominique Duro Marine Joras E. Mortier C. Crenn-Hébert Corinne Floch-Tudal Fabienne Mazy M. Bensalah Agnès Villemant-Uludag A. Lefort Virginie Zarrouk Pierre‐François Ceccaldi Gisèle Philip Gilles Hittinger Martine Malet B. Bachelard Marie Medus Joëlle Dendale-Nguyen Jean-Pierre Brossier Olivier Aubry Jean-Luc Esnault S Léautez Philippe Van de Perre Isabelle Suaud Sandrine-Anne Martha Mahfoud Rouha Pascale Perfezou G Blondin Charles Bellot Séverine Ansart Philippe Le Moine Karine Bages-Jaffuel Jean-Charles Duthé M. Garrè S. Jaffuel Corinne Daniel Christian Calvez C. Beuscart Emmanuelle Boutaric Jennifer Rohan Sylvie Lemoal L. Lassel Ghislaine Cotten Caroline Dupré Esther Beauville C. Arvieux Anabèle Dos Santos Corinne Cudeville Yves Poinsignon Virginie Mouton-Rioux Gaétane Mousset Anne Grellier Philippe Moreau Philippe Tillaut Virginie Mouton-Rioux Odile Luycx-Vaillant Philippe De Morel Marie-Françoise Le Coz Isabelle Belzic M. Niault Anne Vandenbergh C. Janssen Suzanne Braig Virginie Vitrat J. Gaillat Gaëlle Clavere J.P. Bru Blandine Peyret Catherine Mullard Marie Echard Philippe Talon Marjorie Dehlinger Cécile Winter Brigitte Heller-Roussin Odile Launay M Fouchet Ghislaine Firtion Isabelle Goupil E. Pannier Nora Boudjoudi Agnès Bourgeois-Moine M Bodard Valérie Vivier Mandovi Rajguru Virginie Huri Élie Azria

Intrapartum intravenous zidovudine (ZDV) prophylaxis is a long-standing component of prevention mother-to-child transmission (MTCT) human immunodeficiency virus (HIV) in high-resource countries. In some recent guidelines, ZDV no longer systematically recommended for mothers receiving combination antiretroviral therapy (cART) with low viral load. We evaluated the impact according to load and obstetrical conditions. All HIV-1-infected women delivering between 1 January 1997 31 December 2010...

10.1093/cid/cit374 article EN Clinical Infectious Diseases 2013-05-31

BackgroundHuman metapneumovirus (hMPV) is one of the leading respiratory viruses. This prospective observational study aimed to describe clinical features and outcomes hMPV-associated lower tract infections in adult inpatients.MethodsConsecutive patients admitted 31 participating centers with an acute infection a multiplex PCR positive for hMPV were included. A primary composite end point complicated course (hospital death and/or need invasive mechanical ventilation) was used.ResultsBetween...

10.1016/j.heliyon.2024.e33231 article EN cc-by Heliyon 2024-06-18

Pneumococcal diseases (PD) cause considerable morbidity and mortality in adults. V116 is an investigational 21-valent pneumococcal conjugate vaccine (PCV) specifically designed to protect adults from serotypes responsible for the majority of residual PD. This phase 3 study evaluated safety, tolerability, immunogenicity vaccine-experienced ≥50 years.

10.1093/cid/ciae383 article EN cc-by Clinical Infectious Diseases 2024-07-31

Abstract Objectives To analyse the occurrence of virological failure (VF) in patients starting ART with an integrase strand transfer inhibitor (INSTI)-based regimen recent years, relation previous episodes low-level viral load (LLVL). Patients and methods a first between 1 January 2015 31 December 2020 based on two NRTIs one INSTI were included if after control (two measures VL < 50 copies/mL) they had minimum additional measurements. Cox models adjusted for sex, age, acquisition...

10.1093/jac/dkad056 article EN Journal of Antimicrobial Chemotherapy 2023-03-06

Abstract Background Two-drug regimens based on integrase strand transfer inhibitors (INSTIs) and boosted PIs have entered recommended ART. However, INSTIs may not be suitable for all patients. We aimed to report our experience with doravirine/lamivudine as maintenance therapy in people living HIV (PLWH) followed French settings. Methods This observational study enrolled adults who initiated between 1 September 2019 31 October 2021, centres participating the Dat’AIDS cohort. The primary...

10.1093/jac/dkad185 article EN Journal of Antimicrobial Chemotherapy 2023-06-12

Aspirational targets to end AIDS by 2030 include having 95% of people with human immunodeficiency virus (HIV; PWH) diagnosed, treated, and controlled viral load (VL). Our objective was describe, using a large French prospective cohort, the median transition times through cascade care between 2009 2019. We analyzed patients whose first HIV diagnosis made 1 January 31 December Using Kaplan-Meier method, we estimated time linkage (from biological assessment), treatment (date antiretroviral...

10.1093/cid/ciad530 article EN Clinical Infectious Diseases 2023-08-31

Community Acute Bacterial Meningitis (CABM) is a rare infectious disease leading to important impairments. Our aim was describe CABM survivors' quality of life (QOL) 12 months post-CABM and assess its associations with sequelae.Patients included in the COMBAT cohort were evaluated one year after episode. Data collected by questionnaire, via phone calls patients. The WHOQOL-BREF used measure QOL. Hierarchical multivariate linear regressions performed.Study population composed 284 At months,...

10.1371/journal.pone.0281544 article EN cc-by PLoS ONE 2023-03-23
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